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List of works by Mark P Burns

24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury

scientific article

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury

scientific article published on 20 June 2017

Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.

scientific article

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.

scientific article published on 4 April 2018

Cdk5 is a key factor in tau aggregation and tangle formation in vivo

scientific article

Challenges in neurodegeneration research ⬇️

scientific article published on March 10, 2010

Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice

scientific article published on 01 January 2006

Cholesterol independent effect of LXR agonist TO-901317 on gamma-secretase.

scientific article published on May 2007

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques

scientific article

Combination of Fluorescent in situ Hybridization (FISH) and Immunofluorescence Imaging for Detection of Cytokine Expression in Microglia/Macrophage Cells.

scientific article

Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation

scientific article published on 12 October 2013

Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain.

scientific article published on September 2008

Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma

scientific article published on 5 February 2016

Experimental traumatic brain injury induces rapid aggregation and oligomerization of amyloid-beta in an Alzheimer's disease mouse model

scientific article published on 10 December 2013

Glial- and Neuronal-Specific Expression of CCL5 mRNA in the Rat Brain.

scientific article published in January 2017

High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice

scientific article published on 10 May 2021

Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury

scientific article published on 11 March 2014

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

scientific article

Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury

scientific article

NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

scientific article published on 24 March 2017

Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy?

scientific article

Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.

scientific article published on July 2003

Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity.

scientific article published on 24 May 2017

Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317.

scientific article published in July 2007

Sequential Isolation of Microglia and Astrocytes from Young and Aged Adult Mouse Brains for Downstream Transcriptomic Analysis

scientific article published in 2022

Sexual dimorphism in the inflammatory response to traumatic brain injury

scientific article published on 13 June 2017

Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice

scientific article published on 11 September 2017

The Effect of Traumatic Brain Injury on Sleep Architecture and Circadian Rhythms in Mice—A Comparison of High-Frequency Head Impact and Controlled Cortical Injury

scientific article published in 2022

The Effect of the APOE4 Gene on Accumulation of Aβ40 After Brain Injury Cannot Be Reversed by Increasing apoE4 Protein

scientific article published on 12 June 2016

The GABA<sub>A</sub> Receptor Agonist THIP Ameliorates Specific Behavioral Deficits in the Mouse Model of Fragile X Syndrome ⬇️

scientific article published on November 8, 2011

The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement

scientific article

The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice.

scientific article

The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo.

scientific article published on 12 June 2006

The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis.

scientific article published in October 2007

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states ⬇️

scientific article published on December 27, 2012

Tyrosine kinase inhibition reverses TDP-43 effects on synaptic protein expression, astrocytic function and amino acid dis-homeostasis

scientific article published on 10 August 2016

Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease.

scientific article

Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex ⬇️

scientific article published on April 16, 2013

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