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List of works by Irene A Chen

A kinetic study of the growth of fatty acid vesicles

scientific article

A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes.

scientific article published on 14 February 2013

Analysis of Evolutionarily Independent Protein-RNA Complexes Yields a Criterion to Evaluate the Relevance of Prebiotic Scenarios.

scientific article published on 29 January 2018

Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences

scientific article published on 01 October 2017

Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.

scientific article

Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences

scientific article published on 21 December 2012

Comprehensive experimental fitness landscape and evolutionary network for small RNA.

scientific article published on 26 August 2013

Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments.

scientific article

Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages

scientific article published on 13 January 2020

Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor

scientific article (publication date: 14 March 2003)

EasyDIVER: A Pipeline for Assembling and Counting High-Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Peptides

scientific article published on 11 June 2020

Effect of UV Radiation on Fluorescent RNA Aptamers' Functional and Templating Ability

scientific article published on 21 August 2019

Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication

scientific article

Experimental fitness landscapes to understand the molecular evolution of RNA-based life

scientific article published on 29 September 2014

From prelife to life: how chemical kinetics become evolutionary dynamics.

scientific article

From self-assembled vesicles to protocells

scientific article

From underwear to non-equilibrium thermodynamics: physical chemistry informs the origin of life.

scientific article published on 8 July 2016

GE Prize-winning essay. The emergence of cells during the origin of life

scientific article

Genetic drift suppresses bacterial conjugation in spatially structured populations

scientific article published on February 2014

Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes

scientific article published on 05 September 2019

Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model

scientific article

Kinetic sequencing (k-Seq) as a massively parallel assay for ribozyme kinetics: utility and critical parameters

scientific article published on 01 July 2021

Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.

scientific article published on 5 April 2019

Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles

scientific article

Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds

scientific article published on 01 May 2020

Molecular crowding and early evolution.

scientific article

Origin of Life: Protocells Red in Tooth and Claw

scientific article

Prebiotic chemistry: Replicating towards complexity

scientific article published in March 2015

Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences ⬇️

scientific article published on February 7, 2012

Promiscuous Ribozymes and Their Proposed Role in Prebiotic Evolution

scientific article published on 03 February 2020

Quadruplet codons: one small step for a ribosome, one giant leap for proteins: an expanded genetic code could address fundamental questions about algorithmic information, biological function, and the origins of life.

scientific article

RNA catalysis in model protocell vesicles

scientific article (publication date: 28 September 2005)

Rapid Colorimetric Detection of Bacterial Species through the Capture of Gold Nanoparticles by Chimeric Phages

scientific article published on 02 January 2019

Selection for replicases in protocells

scientific article

Shrink-wrap vesicles

scientific article published on December 2005

The RNA World as a Model System to Study the Origin of Life

scientific article

The emergence of competition between model protocells

scientific article

The paradox of dual roles in the RNA world: resolving the conflict between stable folding and templating ability.

scientific article published in September 2013

The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA

scientific article

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