List of works - Liming Zhang

6-Exo-spiro (alkoxycarbonylamino)methyl radical cyclization: highly regio- and stereoselective synthesis of (-)-sibirine.

scientific article published in September 2002

A Bifunctional Ligand Enables Gold-Catalyzed Hydroarylation of Terminal Alkynes under Soft Reaction Conditions

scientific article published on 09 July 2020

A C-H Insertion Approach to Functionalized Cyclopentenones

scientific article published on 8 June 2016

A Desulfonylative Approach in Oxidative Gold Catalysis: Regiospecific Access to Donor-Substituted Acyl Gold Carbenes.

scientific article

A Non-Diazo Strategy to Cyclopropanation via Oxidatively Generated Gold Carbene: the Benefit of A Conformationally Rigid P,N-Bidentate Ligand.

scientific article published on March 2014

A flexible and stereoselective synthesis of azetidin-3-ones through gold-catalyzed intermolecular oxidation of alkynes.

scientific article

A general ligand design for gold catalysis allowing ligand-directed anti-nucleophilic attack of alkynes.

scientific article published on 7 April 2014

A highly efficient preparative method of alpha-ylidene-beta-diketones via Au(III)-catalyzed acyl migration of propargylic esters.

scientific article

A modular, efficient, and stereoselective synthesis of substituted piperidin-4-ols.

scientific article published on November 2010

A non-diazo approach to α-oxo gold carbenes via gold-catalyzed alkyne oxidation.

scientific article

Access to Electron‐Rich Arene‐Fused Hexahydroquinolizinones through a Gold‐Catalysis‐Initiated Cascade Process ⬇️

scientific article published on June 12, 2012

An efficient [2 + 2 + 1] synthesis of 2,5-disubstituted oxazoles via gold-catalyzed intermolecular alkyne oxidation

scientific article published on 12 May 2011

Au- and pt-catalyzed cycloisomerizations of 1,5-enynes to cyclohexadienes with a broad alkyne scope

scientific article published on 01 August 2006

Au-Catalysed oxidative cyclisation.

scientific article published on 19 January 2016

Au-Catalyzed Intermolecular [2+2] Cycloadditions between Chloroalkynes and Unactivated Alkenes

scientific article published on 17 April 2018

Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from N-(pent-2-en-4-ynyl)-beta-lactams

scientific article published on 28 October 2008

AuCl-catalyzed synthesis of benzyl-protected substituted phenols: a formal [3+3] approach

scientific article published on 03 October 2007

Bifunctional Biphenyl-2-ylphosphine Ligand Enables Tandem Gold-Catalyzed Propargylation of Aldehyde and Unexpected Cycloisomerization

scientific article published on 10 December 2018

Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol

scientific article published on 04 June 2018

Bifunctional Phosphine Ligand Enabled Gold-Catalyzed Alkynamide Cycloisomerization: Access to Electron-Rich 2-Aminofurans and Their Diels-Alder Adducts

scientific article published on 15 October 2019

Bifunctional phosphine ligand-enabled gold-catalyzed direct cycloisomerization of alkynyl ketones to 2,5-disubstituted furans

scientific article published on 01 June 2020

Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes.

scientific article

Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives.

scientific article

Chiral Bifunctional Phosphine Ligand Enabling Gold-Catalyzed Asymmetric Isomerization of Alkyne to Allene and Asymmetric Synthesis of 2,5-Dihydrofuran

scientific article published on 21 February 2019

Combining Zn Ion Catalysis with Homogeneous Gold Catalysis: An Efficient Annulation Approach to N-Protected Indoles.

scientific article published on February 2013

Construction of Spironaphthalenones via Gold-Catalyzed Intramolecular Dearomatization Reaction of β-Naphthol Derivatives

scientific article published on 09 July 2020

Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols.

scientific article published on 2 February 2016

DFT study of the mechanisms of in water Au(I)-catalyzed tandem [3,3]-rearrangement/Nazarov reaction/[1,2]-hydrogen shift of enynyl acetates: a proton-transport catalysis strategy in the water-catalyzed [1,2]-hydrogen shift.

scientific article published on 21 November 2007

Designed Bifunctional Phosphine Ligand-Enabled Gold-Catalyzed Isomerizations of Ynamides and Allenamides: Stereoselective and Regioselective Formation of 1-Amido-1,3-dienes

scientific article published on 01 November 2017

Efficient One-Pot Multifunctionalization of Alkynes en Route to α-Alkoxyketones, α-Thioketones, and α-Thio Thioketals by using an Umpolung Strategy

scientific article published on 6 July 2017

Efficient synthesis of cyclopentenones from enynyl acetates via tandem Au(I)-catalyzed 3,3-rearrangement and the Nazarov reaction.

scientific article

Electrophilicity of α-oxo gold carbene intermediates: halogen abstractions from halogenated solvents leading to the formation of chloro/bromomethyl ketones

scientific article published on 14 March 2012

Enantioselective oxidative gold catalysis enabled by a designed chiral P,N-bidentate ligand

scientific article published on 27 November 2014

Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: efficient oxidative union of allylic sulfides and terminal alkynes via C-C bond formation

scientific article published on April 2014

Experimental and computational evidence for gold vinylidenes: generation from terminal alkynes via a bifurcation pathway and facile C-H insertions

scientific article published on 28 December 2011

Gold and Platinum Catalysis of Enyne Cycloisomerization

scholarly article by Liming Zhang et al published November 2006 in Advanced Synthesis & Catalysis

Gold-Catalyzed Direct Assembly of Aryl-Annulated Carbazoles from 2-Alkynyl Arylazides and Alkynes.

scientific article

Gold-Catalyzed Intramolecular Dearomatization Reactions of Indoles for the Synthesis of Spiroindolenines and Spiroindolines

scientific article published on 02 December 2019

Gold-Catalyzed Oxidation of Propargylic Ethers with Internal C-C Triple Bonds: Impressive Regioselectivity Enabled by Inductive Effect.

scientific article published on November 2014

Gold-Catalyzed Silyl-Migrative Cyclization of Homopropargylic Alcohols Enabled by Bifunctional Biphenyl-2-ylphosphine and DFT Studies

scientific article published on 18 September 2019

Gold-Catalyzed Synthesis of Chiral Cyclopentadienyl Esters via Chirality Transfer

scientific article published on 10 August 2020

Gold-catalyzed assembly of heterobicyclic systems.

scientific article published in May 2005

Gold-catalyzed cycloisomerization of siloxy enynes to cyclohexadienes

scientific article published on 01 September 2004

Gold-catalyzed efficient formation of alkenyl enol esters/carbonates from trimethylsilylmethyl-substituted propargyl esters/carbonates

scientific article published on 01 September 2006

Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.

scientific article published on 30 March 2010

Gold-catalyzed highly regioselective oxidation of C-C triple bonds without acid additives: propargyl moieties as masked α,β-unsaturated carbonyls.

scientific article published on October 2010

Gold-catalyzed intramolecular redox reaction of sulfinyl alkynes: efficient generation of alpha-oxo gold carbenoids and application in insertion into R--CO bonds.

scientific article

Gold-catalyzed multiple cascade reaction of 2-alkynylphenylazides with propargyl alcohols

scientific article published on 09 January 2015

Gold-catalyzed one-step construction of 2,3-dihydro-1H-Pyrrolizines with an electron-withdrawing group in the 5-position: a formal synthesis of 7-methoxymitosene

scientific article

Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols.

scientific article published on June 2010

Gold-catalyzed regioselective oxidation of propargylic carboxylates: a reliable access to α-carboxy-α,β-unsaturated ketones/aldehydes

scientific article published on 24 September 2013

Intramolecular Insertions into Unactivated C(sp³)-H Bonds by Oxidatively Generated β-Diketone-α-Gold Carbenes: Synthesis of Cyclopentanones.

scientific article published on 15 April 2015

Ligand-Accelerated Gold-Catalyzed Addition of in Situ Generated Hydrazoic Acid to Alkynes under Neat Conditions.

scientific article published on 11 July 2017

Mechanism of gold(I)-catalyzed rearrangements of acetylenic amine-N-oxides: computational investigations lead to a new mechanism confirmed by experiment.

scientific article published on 22 December 2011

One-Pot Synthesis of Benzene-Fused Medium-Ring Ketones: Gold Catalysis-Enabled Enolate Umpolung Reactivity.

scientific article published on 15 April 2016

One-pot synthesis of fused pyrroles through a key gold-catalysis-triggered cascade.

scientific article published on 30 January 2014

Optimizing P,N-bidentate ligands for oxidative gold catalysis: efficient intermolecular trapping of α-oxo gold carbenes by carboxylic acids.

scientific article published on 2 May 2013

Platinum-catalyzed formation of cyclic-ketone-fused indoles from N-(2-alkynylphenyl)lactams.

scientific article published in January 2008

Practical synthesis of linear alpha-iodo/bromo-alpha,beta-unsaturated aldehydes/ketones from propargylic alcohols via Au/Mo bimetallic catalysis

scientific article published on 01 August 2009

Radical deoxygenation of hydroxyl groups via phosphites.

scientific article published in October 2004

Rapid access to chroman-3-ones through gold-catalyzed oxidation of propargyl aryl ethers.

scientific article published on 13 January 2012

Remote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis.

scientific article published on 23 October 2017

Ruthenium-catalyzed oxidative transformations of terminal alkynes to ketenes by using tethered sulfoxides: access to β-lactams and cyclobutanones

scientific article published on 11 July 2014

Silver-catalyzed stereoselective formation of glycosides using glycosyl ynenoates as donors

scientific article published on 18 July 2018

Soft propargylic deprotonation: designed ligand enables Au-catalyzed isomerization of alkynes to 1,3-dienes.

scientific article published on 17 June 2014

Stereocontrolled synthesis of kelsoene by the homo-favorskii rearrangement.

scientific article published in October 2002

Synthesis of a wakayin model compound: Oxidative formation of a new pyrrole ring in the indol-3-yl-indoloquinone system

Synthesis of bicyclic imidazoles via [2 + 3] cycloaddition between nitriles and regioselectively generated α-imino gold carbene intermediates

scientific article published on 23 August 2012

Synthesis-enabled probing of mitosene structural space leads to improved IC₅₀ over mitomycin C.

scientific article

Tandem au-catalyzed 3,3-rearrangement-[2 + 2] cycloadditions of propargylic esters: expeditious access to highly functionalized 2,3-indoline-fused cyclobutanes.

scientific article published in December 2005

Tempering the reactivities of postulated α-oxo gold carbenes using bidentate ligands: implication of tricoordinated gold intermediates and the development of an expedient bimolecular assembly of 2,4-disubstituted oxazoles

scientific article

The use of Br/Cl to promote regioselective gold-catalyzed rearrangement of propargylic carboxylates: an efficient synthesis of (1Z, 3E)-1-bromo/chloro-2-carboxy-1,3-dienes ⬇️

scientific article published on October 29, 2010

Total Synthesis and Structure Revision of Diplobifuranylone B

scientific article published on 19 August 2019

Total synthesis of (+)-acanthodoral by the use of a Pd-catalyzed metal-ene reaction and a nonreductive 5-exo-acyl radical cyclization

scientific article published on 01 February 2004

Two-step formal [3+2] cycloaddition of enones/enals and allenyl MOM ether: gold-catalyzed highly diastereoselective synthesis of cyclopentanone enol ether containing an all-carbon quaternary center.

scientific article

Wolff Rearrangement of Oxidatively Generated α-Oxo Gold Carbenes: An Effective Approach to Silylketenes

scientific article published on 18 March 2019

[3,3]-Sigmatropic rearrangement versus carbene formation in gold-catalyzed transformations of alkynyl aryl sulfoxides: mechanistic studies and expanded reaction scope

scientific article published on 03 June 2013

List of works by Liming Zhang

6-Exo-spiro (alkoxycarbonylamino)methyl radical cyclization: highly regio- and stereoselective synthesis of (-)-sibirine.

A Bifunctional Ligand Enables Gold-Catalyzed Hydroarylation of Terminal Alkynes under Soft Reaction Conditions

A C-H Insertion Approach to Functionalized Cyclopentenones

A Desulfonylative Approach in Oxidative Gold Catalysis: Regiospecific Access to Donor-Substituted Acyl Gold Carbenes.

A Non-Diazo Strategy to Cyclopropanation via Oxidatively Generated Gold Carbene: the Benefit of A Conformationally Rigid P,N-Bidentate Ligand.

A flexible and stereoselective synthesis of azetidin-3-ones through gold-catalyzed intermolecular oxidation of alkynes.

A general ligand design for gold catalysis allowing ligand-directed anti-nucleophilic attack of alkynes.

A highly efficient preparative method of alpha-ylidene-beta-diketones via Au(III)-catalyzed acyl migration of propargylic esters.

A modular, efficient, and stereoselective synthesis of substituted piperidin-4-ols.

A non-diazo approach to α-oxo gold carbenes via gold-catalyzed alkyne oxidation.

Access to Electron‐Rich Arene‐Fused Hexahydroquinolizinones through a Gold‐Catalysis‐Initiated Cascade Process ⬇️

An efficient [2 + 2 + 1] synthesis of 2,5-disubstituted oxazoles via gold-catalyzed intermolecular alkyne oxidation

Au- and pt-catalyzed cycloisomerizations of 1,5-enynes to cyclohexadienes with a broad alkyne scope

Au-Catalysed oxidative cyclisation.

Au-Catalyzed Intermolecular [2+2] Cycloadditions between Chloroalkynes and Unactivated Alkenes

Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from N-(pent-2-en-4-ynyl)-beta-lactams

AuCl-catalyzed synthesis of benzyl-protected substituted phenols: a formal [3+3] approach

Bifunctional Biphenyl-2-ylphosphine Ligand Enables Tandem Gold-Catalyzed Propargylation of Aldehyde and Unexpected Cycloisomerization

Bifunctional Ligand Enables Efficient Gold-Catalyzed Hydroalkenylation of Propargylic Alcohol

Bifunctional Phosphine Ligand Enabled Gold-Catalyzed Alkynamide Cycloisomerization: Access to Electron-Rich 2-Aminofurans and Their Diels-Alder Adducts

Bifunctional phosphine ligand-enabled gold-catalyzed direct cycloisomerization of alkynyl ketones to 2,5-disubstituted furans

Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes.

Catalytic asymmetric dearomatization (CADA) reactions of phenol and aniline derivatives.

Chiral Bifunctional Phosphine Ligand Enabling Gold-Catalyzed Asymmetric Isomerization of Alkyne to Allene and Asymmetric Synthesis of 2,5-Dihydrofuran

Combining Zn Ion Catalysis with Homogeneous Gold Catalysis: An Efficient Annulation Approach to N-Protected Indoles.

Construction of Spironaphthalenones via Gold-Catalyzed Intramolecular Dearomatization Reaction of β-Naphthol Derivatives

Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols.

DFT study of the mechanisms of in water Au(I)-catalyzed tandem [3,3]-rearrangement/Nazarov reaction/[1,2]-hydrogen shift of enynyl acetates: a proton-transport catalysis strategy in the water-catalyzed [1,2]-hydrogen shift.

Designed Bifunctional Phosphine Ligand-Enabled Gold-Catalyzed Isomerizations of Ynamides and Allenamides: Stereoselective and Regioselective Formation of 1-Amido-1,3-dienes

Efficient One-Pot Multifunctionalization of Alkynes en Route to α-Alkoxyketones, α-Thioketones, and α-Thio Thioketals by using an Umpolung Strategy

Efficient synthesis of cyclopentenones from enynyl acetates via tandem Au(I)-catalyzed 3,3-rearrangement and the Nazarov reaction.

Electrophilicity of α-oxo gold carbene intermediates: halogen abstractions from halogenated solvents leading to the formation of chloro/bromomethyl ketones

Enantioselective oxidative gold catalysis enabled by a designed chiral P,N-bidentate ligand

Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: efficient oxidative union of allylic sulfides and terminal alkynes via C-C bond formation

Experimental and computational evidence for gold vinylidenes: generation from terminal alkynes via a bifurcation pathway and facile C-H insertions

Gold and Platinum Catalysis of Enyne Cycloisomerization

Gold-Catalyzed Direct Assembly of Aryl-Annulated Carbazoles from 2-Alkynyl Arylazides and Alkynes.

Gold-Catalyzed Intramolecular Dearomatization Reactions of Indoles for the Synthesis of Spiroindolenines and Spiroindolines

Gold-Catalyzed Oxidation of Propargylic Ethers with Internal C-C Triple Bonds: Impressive Regioselectivity Enabled by Inductive Effect.

Gold-Catalyzed Silyl-Migrative Cyclization of Homopropargylic Alcohols Enabled by Bifunctional Biphenyl-2-ylphosphine and DFT Studies

Gold-Catalyzed Synthesis of Chiral Cyclopentadienyl Esters via Chirality Transfer

Gold-catalyzed assembly of heterobicyclic systems.

Gold-catalyzed cycloisomerization of siloxy enynes to cyclohexadienes

Gold-catalyzed efficient formation of alkenyl enol esters/carbonates from trimethylsilylmethyl-substituted propargyl esters/carbonates

Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.

Gold-catalyzed highly regioselective oxidation of C-C triple bonds without acid additives: propargyl moieties as masked α,β-unsaturated carbonyls.

Gold-catalyzed intramolecular redox reaction of sulfinyl alkynes: efficient generation of alpha-oxo gold carbenoids and application in insertion into R--CO bonds.

Gold-catalyzed multiple cascade reaction of 2-alkynylphenylazides with propargyl alcohols

Gold-catalyzed one-step construction of 2,3-dihydro-1H-Pyrrolizines with an electron-withdrawing group in the 5-position: a formal synthesis of 7-methoxymitosene

Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols.

Gold-catalyzed regioselective oxidation of propargylic carboxylates: a reliable access to α-carboxy-α,β-unsaturated ketones/aldehydes

Intramolecular Insertions into Unactivated C(sp³)-H Bonds by Oxidatively Generated β-Diketone-α-Gold Carbenes: Synthesis of Cyclopentanones.

Ligand-Accelerated Gold-Catalyzed Addition of in Situ Generated Hydrazoic Acid to Alkynes under Neat Conditions.

Mechanism of gold(I)-catalyzed rearrangements of acetylenic amine-N-oxides: computational investigations lead to a new mechanism confirmed by experiment.

One-Pot Synthesis of Benzene-Fused Medium-Ring Ketones: Gold Catalysis-Enabled Enolate Umpolung Reactivity.

One-pot synthesis of fused pyrroles through a key gold-catalysis-triggered cascade.

Optimizing P,N-bidentate ligands for oxidative gold catalysis: efficient intermolecular trapping of α-oxo gold carbenes by carboxylic acids.

Platinum-catalyzed formation of cyclic-ketone-fused indoles from N-(2-alkynylphenyl)lactams.

Practical synthesis of linear alpha-iodo/bromo-alpha,beta-unsaturated aldehydes/ketones from propargylic alcohols via Au/Mo bimetallic catalysis

Radical deoxygenation of hydroxyl groups via phosphites.

Rapid access to chroman-3-ones through gold-catalyzed oxidation of propargyl aryl ethers.

Remote Cooperative Group Strategy Enables Ligands for Accelerative Asymmetric Gold Catalysis.

Ruthenium-catalyzed oxidative transformations of terminal alkynes to ketenes by using tethered sulfoxides: access to β-lactams and cyclobutanones

Silver-catalyzed stereoselective formation of glycosides using glycosyl ynenoates as donors

Soft propargylic deprotonation: designed ligand enables Au-catalyzed isomerization of alkynes to 1,3-dienes.

Stereocontrolled synthesis of kelsoene by the homo-favorskii rearrangement.

Synthesis of a wakayin model compound: Oxidative formation of a new pyrrole ring in the indol-3-yl-indoloquinone system

Synthesis of bicyclic imidazoles via [2 + 3] cycloaddition between nitriles and regioselectively generated α-imino gold carbene intermediates

Synthesis-enabled probing of mitosene structural space leads to improved IC₅₀ over mitomycin C.

Tandem au-catalyzed 3,3-rearrangement-[2 + 2] cycloadditions of propargylic esters: expeditious access to highly functionalized 2,3-indoline-fused cyclobutanes.

Tempering the reactivities of postulated α-oxo gold carbenes using bidentate ligands: implication of tricoordinated gold intermediates and the development of an expedient bimolecular assembly of 2,4-disubstituted oxazoles

The use of Br/Cl to promote regioselective gold-catalyzed rearrangement of propargylic carboxylates: an efficient synthesis of (1Z, 3E)-1-bromo/chloro-2-carboxy-1,3-dienes ⬇️

Total Synthesis and Structure Revision of Diplobifuranylone B

Total synthesis of (+)-acanthodoral by the use of a Pd-catalyzed metal-ene reaction and a nonreductive 5-exo-acyl radical cyclization

Two-step formal [3+2] cycloaddition of enones/enals and allenyl MOM ether: gold-catalyzed highly diastereoselective synthesis of cyclopentanone enol ether containing an all-carbon quaternary center.

Wolff Rearrangement of Oxidatively Generated α-Oxo Gold Carbenes: An Effective Approach to Silylketenes

[3,3]-Sigmatropic rearrangement versus carbene formation in gold-catalyzed transformations of alkynyl aryl sulfoxides: mechanistic studies and expanded reaction scope