List of works - Geoffrey A Mueller

100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology

scientific article

A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy

scientific article published on 25 September 2019

A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda.

scientific article published on 26 June 2008

A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization

scientific article

A method for incorporating dipolar couplings into structure calculations in cases of (near) axial symmetry of alignment

scientific article published on 01 November 2000

A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins

scientific article published on 01 April 1999

A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction.

scientific article

APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.

scientific article

Allergens and their associated small molecule ligands-their dual role in sensitization

scientific article published in August 2021

Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis

scientific article

Analytical solution to the coupled evolution of multidimensional NMR data

scientific article

Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity

scientific article

Are allergens more abundant and/or more stable than other proteins in pollens and dust?

scientific article published on 21 November 2019

Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?

scientific article published on 13 October 2016

Asymmetric conformational maturation of HIV-1 reverse transcriptase

scientific article published on 3 June 2015

Bet v 1 and other birch allergens are more resistant to proteolysis and more abundant than other birch pollen proteins

scientific article published on 07 January 2022

Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity

scientific article

Characterization of the redox transition of the XRCC1 N-terminal domain

scientific article published on 13 November 2014

Comparison of a neural net-based QSAR algorithm (PCANN) with Hologram- and multiple linear regression-based QSAR approaches: application to 1,4-dihydropyridine-based calcium channel antagonists.

scientific article published in May 2001

Complementation of Der P 2-induced histamine release from human basophils sensitized with monoclonal IgE: not only by IgE, but also by IgG antibodies directed to a nonoverlapping epitope of Der p 2

scientific article published on 01 March 1998

Der p 5 Crystal Structure Provides Insight into the Group 5 Dust Mite Allergens

scientific article

Direct structure refinement of high molecular weight proteins against residual dipolar couplings and carbonyl chemical shift changes upon alignment: an application to maltose binding protein

scientific article published on September 1, 2001

Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase beta.

scientific article

Enhanced Approaches for Identifying Amadori Products: Application to Peanut Allergens.

scientific article published on 25 January 2016

Expression and Secondary Structure Determination by NMR Methods of the Major House Dust Mite Allergen Der p 2 ⬇️

scientific article published on October 24, 1997

Genomic, RNAseq, and molecular modeling evidence suggests that the major allergen domain in insects evolved from a homodimeric origin

scientific article published on January 2013

Homodimerization of the p51 subunit of HIV-1 reverse transcriptase.

scientific article published on April 2010

Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

scientific article published on 04 December 2019

Identification of Maillard reaction products on peanut allergens that influence binding to the receptor for advanced glycation end products.

scientific article

Identification of the amino-terminal fragment of Ara h 1 as a major target of the IgE-binding activity in the basic peanut protein fraction

scientific article published on 07 February 2020

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2

scientific article published on 09 September 2020

Metal and ligand binding to the HIV-RNase H active site are remotely monitored by Ile556

scientific article

Metal-induced DNA translocation leads to DNA polymerase conformational activation ⬇️

scientific article published on December 14, 2011

Mouse/human chimeric IgG1 and IgG4 antibodies directed to the house dust mite allergen Der p 2: use in quantification of allergen specific IgG.

scientific article published on September 1997

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

scientific article published on 08 October 2019

NIAID, NIEHS, NHLBI, and MCAN workshop report: the indoor environment and childhood asthma - implications for home environmental intervention in asthma prevention and management

journal article published in 2017

NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution

scientific article published on 02 August 2007

NMR assignment of polymerase beta labeled with 2H, 13C, and 15N in complex with substrate DNA.

scientific article published on July 2007

NMR assignment of protein side chains using residue-correlated labeling and NOE spectra.

scientific article

NMR studies of the interaction of a type II dihydrofolate reductase with pyridine nucleotides reveal unexpected phosphatase and reductase activity

scientific article published in September 2003

New Insights into Cockroach Allergens

scientific article

Orienting domains in proteins using dipolar couplings measured by liquid-state NMR: differences in solution and crystal forms of maltodextrin binding protein loaded with beta-cyclodextrin

scientific article published on 01 February 2000

Phage like it HOT: solution structure of the bacteriophage P1-encoded HOT protein, a homolog of the theta subunit of E. coli DNA polymerase III

scientific article published on 01 December 2004

Primary Identification, Biochemical Characterization, and Immunologic Properties of the Allergenic Pollen Cyclophilin Cat r 1

scientific article

Protein-mediated antagonism between HIV reverse transcriptase ligands nevirapine and MgATP.

scientific article published on June 2013

Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation

scientific article

Serological, genomic and structural analyses of the major mite allergen Der p 23.

scientific article published on 25 November 2015

Solution structure of the Drosha double-stranded RNA-binding domain

scientific article

Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium

scientific article

Structural studies of the PARP-1 BRCT domain

scientific article

Tertiary structure of the major house dust mite allergen Der p 2: sequential and structural homologies

scientific article

The Draft Genome Assembly of Dermatophagoides pteronyssinus Supports Identification of Novel Allergen Isoforms in Dermatophagoides Species

scientific article published on 11 January 2018

The N-terminal domain of the Drosophila histone mRNA binding protein, SLBP, is intrinsically disordered with nascent helical structure

scientific article

The crystal structure of a major dust mite allergen Der p 2, and its biological implications

scientific article

The molecular basis of peanut allergy

scientific article published on May 2014

The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment

scientific article

The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins

scientific article

Unfolding the HIV-1 reverse transcriptase RNase H domain--how to lose a molecular tug-of-war

scientific article published on 14 January 2016

List of works by Geoffrey A Mueller

100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology

A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy

A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda.

A metabolomic, geographic, and seasonal analysis of the contribution of pollen-derived adenosine to allergic sensitization

A method for incorporating dipolar couplings into structure calculations in cases of (near) axial symmetry of alignment

A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins

A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction.

APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.

Allergens and their associated small molecule ligands-their dual role in sensitization

Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis

Analytical solution to the coupled evolution of multidimensional NMR data

Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity

Are allergens more abundant and/or more stable than other proteins in pollens and dust?

Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?

Asymmetric conformational maturation of HIV-1 reverse transcriptase

Bet v 1 and other birch allergens are more resistant to proteolysis and more abundant than other birch pollen proteins

Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity

Characterization of the redox transition of the XRCC1 N-terminal domain

Comparison of a neural net-based QSAR algorithm (PCANN) with Hologram- and multiple linear regression-based QSAR approaches: application to 1,4-dihydropyridine-based calcium channel antagonists.

Complementation of Der P 2-induced histamine release from human basophils sensitized with monoclonal IgE: not only by IgE, but also by IgG antibodies directed to a nonoverlapping epitope of Der p 2

Der p 5 Crystal Structure Provides Insight into the Group 5 Dust Mite Allergens

Direct structure refinement of high molecular weight proteins against residual dipolar couplings and carbonyl chemical shift changes upon alignment: an application to maltose binding protein

Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase beta.

Enhanced Approaches for Identifying Amadori Products: Application to Peanut Allergens.

Expression and Secondary Structure Determination by NMR Methods of the Major House Dust Mite Allergen Der p 2 ⬇️

Genomic, RNAseq, and molecular modeling evidence suggests that the major allergen domain in insects evolved from a homodimeric origin

Homodimerization of the p51 subunit of HIV-1 reverse transcriptase.

Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

Identification of Maillard reaction products on peanut allergens that influence binding to the receptor for advanced glycation end products.

Identification of the amino-terminal fragment of Ara h 1 as a major target of the IgE-binding activity in the basic peanut protein fraction

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2

Metal and ligand binding to the HIV-RNase H active site are remotely monitored by Ile556

Metal-induced DNA translocation leads to DNA polymerase conformational activation ⬇️

Mouse/human chimeric IgG1 and IgG4 antibodies directed to the house dust mite allergen Der p 2: use in quantification of allergen specific IgG.

Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity

NIAID, NIEHS, NHLBI, and MCAN workshop report: the indoor environment and childhood asthma - implications for home environmental intervention in asthma prevention and management

NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution

NMR assignment of polymerase beta labeled with 2H, 13C, and 15N in complex with substrate DNA.

NMR assignment of protein side chains using residue-correlated labeling and NOE spectra.

NMR studies of the interaction of a type II dihydrofolate reductase with pyridine nucleotides reveal unexpected phosphatase and reductase activity

New Insights into Cockroach Allergens

Orienting domains in proteins using dipolar couplings measured by liquid-state NMR: differences in solution and crystal forms of maltodextrin binding protein loaded with beta-cyclodextrin

Phage like it HOT: solution structure of the bacteriophage P1-encoded HOT protein, a homolog of the theta subunit of E. coli DNA polymerase III

Primary Identification, Biochemical Characterization, and Immunologic Properties of the Allergenic Pollen Cyclophilin Cat r 1

Protein-mediated antagonism between HIV reverse transcriptase ligands nevirapine and MgATP.

Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation

Serological, genomic and structural analyses of the major mite allergen Der p 23.

Solution structure of the Drosha double-stranded RNA-binding domain

Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium

Structural studies of the PARP-1 BRCT domain

Tertiary structure of the major house dust mite allergen Der p 2: sequential and structural homologies

The Draft Genome Assembly of Dermatophagoides pteronyssinus Supports Identification of Novel Allergen Isoforms in Dermatophagoides Species

The N-terminal domain of the Drosophila histone mRNA binding protein, SLBP, is intrinsically disordered with nascent helical structure

The crystal structure of a major dust mite allergen Der p 2, and its biological implications

The molecular basis of peanut allergy

The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment

The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins

Unfolding the HIV-1 reverse transcriptase RNase H domain--how to lose a molecular tug-of-war