List of works - Guido Ferrari

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

scientific article (publication date: 5 April 2012)

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

scientific article published on June 2009

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

scientific article published on 4 January 2012

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

scientific article

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

scientific article

Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination

scientific article

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.

scientific article published on 9 May 2013

A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

scientific article published on 01 February 2002

Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers

scientific article published on May 2009

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

scientific article

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

scientific article

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

scientific article (publication date: August 2011)

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

scientific article published on 18 December 2013

Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

scientific article

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

scientific article

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape

scientific article

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

scientific article

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines

scientific article

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

scientific article

Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

scientific article published on 18 December 2013

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

scientific article published on 30 May 2016

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial

scientific article

Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine

scientific article (publication date: July 2011)

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

scientific article

T Cell Assays and MIATA: The Essential Minimum for Maximum Impact

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection

scientific article

Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination

scientific article

Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells

scientific article

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

scientific article

Discriminating between latent and active tuberculosis with multiple biomarker responses.

scientific article

Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial

scientific article published on February 2007

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

scientific article

Lack of infection in HIV-exposed individuals is associated with a strong CD8(+) cell noncytotoxic anti-HIV response

scientific article published on 01 February 1999

Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers

scientific article published on 10 August 2006

FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

scientific article

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

scientific article published on 2 May 2012

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design

scientific article published on 28 May 2008

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection

scientific article

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

scientific article

Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials

scientific article published in January 2005

SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses

scientific article published on 15 December 2011

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

scientific article published on July 2013

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

scientific article

Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication

scientific article

Safety and immunogenicity of cytotoxic T-lymphocyte poly-epitope, DNA plasmid (EP HIV-1090) vaccine in healthy, human immunodeficiency virus type 1 (HIV-1)-uninfected adults

scientific article published on 20 November 2007

Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

scientific article (publication date: 10 May 2011)

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

scientific article

Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees

scientific article published on 08 May 2013

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure

scientific article published on 16 January 2013

List of works by Guido Ferrari

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.

A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial

Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

T Cell Assays and MIATA: The Essential Minimum for Maximum Impact

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection

Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination

Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

Discriminating between latent and active tuberculosis with multiple biomarker responses.

Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

Lack of infection in HIV-exposed individuals is associated with a strong CD8(+) cell noncytotoxic anti-HIV response

Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers

FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials

SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication

Safety and immunogenicity of cytotoxic T-lymphocyte poly-epitope, DNA plasmid (EP HIV-1090) vaccine in healthy, human immunodeficiency virus type 1 (HIV-1)-uninfected adults

Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees

Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure