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List of works by Denis J David

A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors

scientific article published on 29 June 2016

A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment.

scientific article published on 26 September 2013

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

scientific article

Adult hippocampal neurogenesis: an actor in the antidepressant-like action.

scientific article published on 04 April 2013

Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice

scientific article

Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice.

scientific article published on 28 May 2013

Antidepressant and tolerance: Determinants and management of major side effects

scientific article published on 13 July 2016

Antidepressant-like Effects of Electroconvulsive Seizures Require Adult Neurogenesis in a Neuroendocrine Model of Depression.

scientific article

Antidepressant-like effects in various mice strains in the forced swimming test.

scientific article published on 25 February 2003

Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression.

scientific article

BDNF/TRKB/P75NTR polymorphisms and their consequences on antidepressant efficacy in depressed patients.

scientific article published on 30 June 2015

Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety

scientific article published on 08 April 2011

Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice.

scientific article published on 25 January 2006

Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype.

scientific article

Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.

scientific article published on 17 February 2011

Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression

scientific article published on 2 February 2016

Chronic corticosterone administration effects on behavioral emotionality in female c57bl6 mice.

scientific article published on 13 March 2017

Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells.

scientific article published in February 2008

Cognitive Dysfunction in Major Depressive Disorder. A Translational Review in Animal Models of the Disease

scientific article

Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.

scientific article

Defective interleukin-2-dependent STAT5 signalling in CD8 T lymphocytes from HIV-positive patients: restoration by antiretroviral therapy.

scientific article

Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression

scientific article published on 16 August 2017

Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity

scientific article published on 16 April 2015

Downregulation of the expression of the main immunoglobulin V(H) family in HIV-infected patients: modulation by triple combination therapy

scientific article published on 01 February 1999

Effects of acute treatment with paroxetine, citalopram and venlafaxine in vivo on noradrenaline and serotonin outflow: a microdialysis study in Swiss mice

scientific article

Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors.

scientific article published on April 2003

Escitalopram and citalopram: the unexpected role of the R-enantiomer

scientific article

Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration.

scientific article published on 26 October 2011

Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach.

scientific article

Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.

scientific article

Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment.

scientific article

Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse

scientific article

Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.

scientific article published in May 2013

Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation ⬇️

scientific article published on December 9, 2011

In vivo electrochemical studies of dopamine clearance in subregions of rat nucleus accumbens: differential properties of the core and shell.

scientific article published in October 1998

Increased fear response to contextual cues in mice lacking the 5-HT1A receptor.

scientific article published in January 2006

Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents.

scientific article published on 4 April 2008

Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion

scientific article

Involvement of Bcl-2 and IL-2R in HIV-positive patients whose CD4 cell counts fail to increase rapidly with highly active antiretroviral therapy.

scientific article

Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior

scientific article

Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice.

scientific article published on 17 May 2016

Learning and memory impairments in a neuroendocrine mouse model of anxiety/depression

scientific article

Mechanisms of action of antidepressive drugs: new approaches ⬇️

scientific article published on 01 December 2012

Methemoglobinemia as a biomarker of dapsone-induced mania severity

scientific article published on 25 December 2018

Modeling treatment-resistant depression.

scientific article

Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models

scientific article published in Nature Communications

Monoamine metabolism changes following the mouse forced swimming test but not the tail suspension test.

scientific article published in August 2003

Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms

scientific article published on 23 April 2014

NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration.

scientific article published on 6 June 2014

Neurobiological mechanisms of stress resilience and implications for the aged population.

scientific article

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.

scientific article published on May 2009

Neurogenesis-dependent and independent effects of anti-depressant drugs

scientific article published in October 2009

Nicotine-evoked nitric oxide release in the rat hippocampal slice.

scientific article published in October 1998

No impact of eight NTRK2 genetic polymorphisms on 6-month antidepressant efficacy in depressed patients.

scientific article published on 17 February 2017

Nrf2-signaling and BDNF: A new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression.

scientific article published on 24 April 2015

Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens

scientific article published on 12 December 2017

Pharmacological properties of vortioxetine and its pre-clinical consequences

scientific article published in February 2016

Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients

scientific article published on 23 August 2017

Prophylactic efficacy of 5-HT4R agonists against stress

scientific article published on 10 October 2019

Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism

scientific article

Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment.

scientific article

Restless Legs Syndrome and Schizophrenia: A Case Report.

scientific article published on 6 December 2017

Récepteurs 5-HT1B de la sérotonine et effets antidépresseurs des inhibiteurs de recapture sélectifs de la sérotonine

scientific article published on 01 May 2001

S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice.

scientific article

S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms.

scientific article published on 19 July 2017

Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice.

scientific article published on May 2004

Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety

scientific article

Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice

scientific journal article

Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice.

scientific article published on 23 February 2009

The Catechol-O-methyltransferase Val(108/158)Met Genetic Polymorphism cannot be Recommended as a Biomarker for the Prediction of Venlafaxine Efficacy in Patients Treated in Psychiatric Settings

scientific article published on 19 June 2017

The TRKB rs2289656 genetic polymorphism is associated with acute suicide attempts in depressed patients: A transversal case control study

scientific article published in PLoS ONE

The association of β-arrestin2 polymorphisms with response to antidepressant treatment in depressed patients

scientific article published on 12 October 2017

Vortioxetine Improves Context Discrimination in Mice Through a Neurogenesis Independent Mechanism.

scientific article published on 12 March 2018

Vortioxetine for the treatment of major depressive disorder.

scientific article

When ageing meets the blues: Are current antidepressants effective in depressed aged patients?

scientific article published on 06 June 2015

[Consequences of the monoaminergic systems cross-talk in the antidepressant activity]

scientific article published on 22 May 2018

[The pharmacological basis of the serotonin system: Application to antidepressant response]

scientific article published on 23 April 2016

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