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List of works by Luca Varani

A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential

scientific article published on September 2017

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

article

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

scientific article

Antibody Binding Modulates Conformational Exchange in Domain III of Dengue Virus E Protein

scientific article

Changes in sidechain and backbone dynamics identify determinants of specificity in RNA recognition by human U1A protein

scientific article published on 01 April 2000

Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin.

scientific article

Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells.

scientific article published on 16 September 2015

Elucidation of the Interleukin-15 Binding Site on Its Alpha Receptor by NMR

article

Epitope mapping by solution NMR spectroscopy

scientific article published on 27 February 2015

Gold nanoparticles downregulate interleukin-1β-induced pro-inflammatory responses.

scientific article

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

scientific article

Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex.

scientific article

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

scientific article published on 6 August 2012

Opening Study on the Development of a New Biosensor for Metal Toxicity Based on Pseudomonas fluorescens Pyoverdine

scientific article published on 10 December 2013

Partially folded structure of monomeric bovine β-lactoglobulin

scientific article published on 01 March 1996

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

scientific article

Rapid structural characterization of human antibody-antigen complexes through experimentally validated computational docking

scientific article published on 4 January 2010

Rational engineering of a human anti-dengue antibody through experimentally validated computational docking

scientific article

Rational modification of estrogen receptor by combination of computational and experimental analysis

scientific article

Rationally modified estrogen receptor protein as a bio-recognition element for the detection of EDC pollutants: strategies and opportunities

scientific article

Receptor-based high-throughput screening and identification of estrogens in dietary supplements using bioaffinity liquid-chromatography ion mobility mass spectrometry

scientific article

Solution mapping of T cell receptor docking footprints on peptide-MHC.

scholarly article

Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection

scientific article

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

scientific article published on September 2010

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells

scientific article published on 29 June 2016

The immune receptor Tim-3 mediates activation of PI3 kinase/mTOR and HIF-1 pathways in human myeloid leukaemia cells

scientific article