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List of works by Jean-Paul Renaud

3,5-T2 is an alternative ligand for the thyroid hormone receptor β1.

scientific article published on 4 June 2013

A canonical structure for the ligand-binding domain of nuclear receptors

scientific article published on 01 January 1996

A canonical structure for the ligand-binding domain of nuclear receptors

scientific article published on 01 February 1996

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

scientific article

Amphioxus postembryonic development reveals the homology of chordate metamorphosis.

scientific article published in June 2008

Binding of ligands and activation of transcription by nuclear receptors.

scientific article

Biophysics in drug discovery: impact, challenges and opportunities.

scientific article

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

scientific article

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

scientific article published in December 1997

Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy.

scientific article published in December 2003

Cryo-EM in drug discovery: achievements, limitations and prospects

article

Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering

scientific article published on 01 June 1990

Fragment-Based Drug Design: Computational and Experimental State of the Art ⬇️

scientific article published on July 1, 2011

High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine

scientific article published on 01 August 1994

In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE.

scientific article

International Union of Pharmacology. LXVI. Orphan nuclear receptors

scientific article

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

scientific article published on 10 August 2015

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s

scientific article published on 01 April 1993

Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.

scientific article published on January 1997

Recombinant yeast in drug metabolism.

scientific article published on October 1993

Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes

scientific article published on 01 August 1999

Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins

scientific article published on 01 February 1990

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

scientific article

Structural studies on nuclear receptors.

scientific article

Structure-function analysis of the Rev-erbA and RVR ligand-binding domains reveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains

scientific article published on 01 May 2000

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

scientific article published in May 2003

Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes.

scientific article published on November 1996

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

scientific article

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