List of works - Xavier Altafaj

A store-operated Ca2+ influx activated in response to the depletion of thapsigargin-sensitive Ca2+ stores is developmentally regulated in embryonic cortical neurons from mice.

scientific article published in September 2005

Adenosine A1-A2A Receptor Heteromer as a Possible Target for Early-Onset Parkinson's Disease

scientific article published on 22 November 2017

An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

scientific article published on 01 January 2021

Caveolin-3 is a direct molecular partner of the Cav1.1 subunit of the skeletal muscle L-type calcium channel

scientific article published on 22 January 2011

Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases

scientific journal article

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

scientific article

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

scientific article

Diseases of the Synaptic Vesicle: A Potential New Group of Neurometabolic Disorders Affecting Neurotransmission.

scientific article published on 15 November 2016

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

scientific article (publication date: 28 February 2003)

Gene therapy for Down syndrome.

scientific article published on January 2012

Glutamate receptor mutations in psychiatric and neurodevelopmental disorders

scientific article published on January 2014

Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons.

scientific article published on 19 August 2016

Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

scientific article

Insights from mouse models to understand neurodegeneration in Down syndrome

scientific article published on August 2010

L-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy

scientific article published on 18 June 2019

Maurocalcine and domain A of the II-III loop of the dihydropyridine receptor Cav 1.1 subunit share common binding sites on the skeletal ryanodine receptor.

scientific article published on 9 December 2004

Maurocalcine interacts with the cardiac ryanodine receptor without inducing channel modification

scientific article published on September 2007

Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation

scientific article published on 01 October 2018

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

scientific article

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

scientific article published on 5 December 2012

Oocyte expression with injection of purified T7 RNA polymerase.

scientific article

Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome.

scientific article

Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement

scientific article

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

scientific article

The antigen-binding fragment of human gamma immunoglobulin prevents amyloid β-peptide folding into β-sheet to form oligomers.

scientific article published on 13 April 2017

The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1

scientific journal article

Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane

scientific article

Zinc transporter-1 concentrates at the postsynaptic density of hippocampal synapses.

scientific article

List of works by Xavier Altafaj

A store-operated Ca2+ influx activated in response to the depletion of thapsigargin-sensitive Ca2+ stores is developmentally regulated in embryonic cortical neurons from mice.

Adenosine A1-A2A Receptor Heteromer as a Possible Target for Early-Onset Parkinson's Disease

An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

Caveolin-3 is a direct molecular partner of the Cav1.1 subunit of the skeletal muscle L-type calcium channel

Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

Diseases of the Synaptic Vesicle: A Potential New Group of Neurometabolic Disorders Affecting Neurotransmission.

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

Gene therapy for Down syndrome.

Glutamate receptor mutations in psychiatric and neurodevelopmental disorders

Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons.

Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

Insights from mouse models to understand neurodegeneration in Down syndrome

L-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy

Maurocalcine and domain A of the II-III loop of the dihydropyridine receptor Cav 1.1 subunit share common binding sites on the skeletal ryanodine receptor.

Maurocalcine interacts with the cardiac ryanodine receptor without inducing channel modification

Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

Oocyte expression with injection of purified T7 RNA polymerase.

Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome.

Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

The antigen-binding fragment of human gamma immunoglobulin prevents amyloid β-peptide folding into β-sheet to form oligomers.

The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1

Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane

Zinc transporter-1 concentrates at the postsynaptic density of hippocampal synapses.