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List of works by Sophie Paczesny

A biomarker panel for acute graft-versus-host disease

scientific article published on 02 October 2008

Acute Graft-Versus-Host Disease Prognosis: Are Biomarkers Ready for Preemptive Clinical Trials?

scientific article published on 07 July 2017

Acute graft-versus-host disease biomarkers measured during therapy can predict treatment outcomes: a Blood and Marrow Transplant Clinical Trials Network study

scientific article published in March 2012

Acute graft-versus-host disease: new treatment strategies

scientific article

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

scientific article

Application of serum proteomics to the Women's Health Initiative conjugated equine estrogens trial reveals a multitude of effects relevant to clinical findings

scientific article published on 29 April 2009

Aqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISA

scientific article

Aqueous two-phase systems enable multiplexing of homogeneous immunoassays

scientific article

Assessment of ST2 for risk of death following graft-versus-host disease in pediatric and adult age groups

scientific article published on 23 January 2020

Association of Plasma CD163 Concentration with De Novo-Onset Chronic Graft-versus-Host Disease

scientific article published on 25 April 2017

Baseline body mass index among children and adults undergoing allogeneic hematopoietic cell transplantation: clinical characteristics and outcomes.

scientific article

Bcl6 and Blimp1 reciprocally regulate ST2+ Treg cell development in the context of allergic airway inflammation

scientific article published on 13 March 2020

Biomarker Panel for Chronic Graft-Versus-Host Disease

scientific article published on 23 May 2016

Biomarkers for Allogeneic HCT Outcomes

scientific article published on 21 April 2020

Biomarkers for Diagnosis and Prognosis of Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation

scientific article

Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation

scientific article published on 18 December 2018

Biomarkers for fatal immune response to stem cell treatment could reduce mortality

scientific article

Biomarkers for post-transplantation outcomes

scientific article published on 5 April 2018

Biomarkers in chronic graft-versus-host disease: quo vadis?

scientific article

Boosting vaccinations with peptide-pulsed CD34+ progenitor-derived dendritic cells can expand long-lived melanoma peptide-specific CD8+ T cells in patients with metastatic melanoma

scientific article published in March 2005

CXCL10: most consistent cGVHD biomarker?

scientific article published on June 2016

Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival.

scientific article published on 23 May 2008

Clinical Proteomics for Post-Hematopoeitic Stem Cell Transplantation Outcomes

scientific article published on 17 October 2018

Clinical applications for biomarkers of acute and chronic graft-versus-host disease

scientific article published on January 2012

Clofarabine and busulfan conditioning facilitates engraftment and provides significant antitumor activity in nonremission hematologic malignancies

scientific article published on 12 August 2011

Dendritic cells as vectors for immunotherapy of cancer

scientific article published on December 2003

Dendritic cells: controllers of the immune system and a new promise for immunotherapy

scientific article

Diagnostic and Prognostic Plasma Biomarkers for Idiopathic Pneumonia Syndrome after Hematopoietic Cell Transplantation

scientific article published on 6 December 2017

Discovery and validation of graft-versus-host disease biomarkers ⬇️

scientific article published on November 19, 2012

Donor HLA-E Status Associates with Disease-Free Survival and Transplant-Related Mortality after Non In Vivo T Cell-Depleted HSCT for Acute Leukemia

scientific article published on 16 August 2019

Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation

scientific article published on 27 January 2016

Early high plasma ST2, the decoy IL-33 receptor, in children undergoing hematopoietic cell transplantation is associated with the development of post-transplant diabetes mellitus

scientific article published on 29 August 2019

Editorial: Danger Signals Triggering Immune Response and Inflammation.

scientific article published on 11 August 2017

Efficient generation of CD34+ progenitor-derived dendritic cells from G-CSF-mobilized peripheral mononuclear cells does not require hematopoietic stem cell enrichment

scientific article published on 17 January 2007

Elafin is a biomarker of graft-versus-host disease of the skin

scientific article

Engraftment syndrome after allogeneic hematopoietic cell transplantation predicts poor outcomes.

scientific article

Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease

scientific article published on 27 November 2007

Etanercept plus topical corticosteroids as initial therapy for grade one acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

scientific article

Ex vivo culture of mouse skin activates an interleukin 1 alpha-dependent inflammatory response

scientific article published on 16 October 2019

Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells

scientific article

Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease

scientific article

From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.

scientific article published on 26 July 2018

GVHD risk assessment beyond current HLA evaluation

scientific article published on 25 October 2019

Graft-Versus-Host Disease-Free Antitumoral Signature After Allogeneic Donor Lymphocyte Injection Identified by Proteomics and Systems Biology

scientific article published on 23 May 2019

Graft-versus-host disease biomarkers: omics and personalized medicine

scientific article

HLA-B leads survival after HCT

scientific article published on 01 July 2020

High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation

scientific article

High throughput sequential ELISA for validation of biomarkers of acute graft-versus-host disease

scientific article published on 31 October 2012

Human mesenchymal stem cells license adult CD34+ hemopoietic progenitor cells to differentiate into regulatory dendritic cells through activation of the Notch pathway.

scientific article published in February 2008

ICOSL+ plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist

scientific article published on 01 October 2020

Immunotherapeutic Concepts to Target Acute Myeloid Leukemia: Focusing on the Role of Monoclonal Antibodies, Hypomethylating Agents and the Leukemic Microenvironment

scientific article published on 31 July 2017

Immunotherapy through T-cell receptor gene transfer induces severe graft-versus-host disease

scientific article published on November 2010

Immunotherapy via dendritic cells

scientific article

Improved reproducibility and quality of GvHD biomarker assay: application of multiplex microfluidic channel system

scientific article published on 05 September 2016

Introduction to a review series on emerging immunotherapies for hematologic diseases

scientific article published on 04 May 2018

Investigation of donor KIR content and matching in children undergoing hematopoietic cell transplantation for acute leukemia

scientific article published on 01 April 2020

JAK polymorphisms: jack of all cytokines, masters GVHD?

scientific article published on 09 August 2016

Less cholesterol means better tumor killing for cytotoxic T9 cells

scientific article published on 15 May 2018

Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells

scientific article published on 6 December 2005

Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.

scientific article published on 22 February 2018

Measuring melanoma-specific cytotoxic T lymphocytes elicited by dendritic cell vaccines with a tumor inhibition assay in vitro.

scientific article published on March 2005

Mesenchymal stem cells for treatment and prevention of graft-versus-host disease after allogeneic hematopoietic cell transplantation

scientific article published on September 2009

Metabolic Complications Precede Alloreactivity and Are Characterized by Changes in Suppression of Tumorigenicity 2 Signaling

scientific article published on 21 December 2016

Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths

scientific article published on 01 August 2019

Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients

scientific article published on 18 January 2018

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: III. The 2014 Biomarker Working Group Report.

scientific article published on 30 January 2015

National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Immune Dysregulation and Pathobiology Working Group Report

scientific article published on 14 October 2016

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses

scientific article published on 15 December 2017

Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling

scientific article

Opportunities and challenges of proteomics in pediatric patients: circulating biomarkers after hematopoietic stem cell transplantation as a successful example

scientific article

Plasma CXCL9 elevations correlate with chronic GVHD diagnosis.

scientific article published on 20 December 2013

Plasma biomarkers in graft-versus-host disease: a new era?

scientific article published on January 2009

Plasma biomarkers of lower gastrointestinal and liver acute GVHD.

scientific article published on 27 January 2012

Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT.

scientific article

Plasma elevations of tumor necrosis factor-receptor-1 at day 7 postallogeneic transplant correlate with graft-versus-host disease severity and overall survival in pediatric patients

scientific article published on July 2008

Plasma proteome profiling of a mouse model of breast cancer identifies a set of up-regulated proteins in common with human breast cancer cells.

scientific article

Plasma-derived proteomic biomarkers in human leukocyte antigen-haploidentical or human leukocyte antigen-matched bone marrow transplantation using post-transplantation cyclophosphamide

scientific article published on 25 January 2017

Post-haematopoietic cell transplantation outcomes: why ST2 became a 'golden nugget' biomarker

scientific article published on 10 February 2020

Postmenopausal estrogen and progestin effects on the serum proteome

scientific article

Preprogrammed capillarity to passively control system-level sequential and parallel microfluidic flows

scientific article published on June 2013

Preprogrammed, parallel on-chip immunoassay using system-level capillarity control

scientific article

Prognostic biomarkers for acute graft-versus-host disease risk after cyclophosphamide-fludarabine nonmyeloablative allotransplantation

scientific article

Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation

scientific article published on 17 June 2020

Proteomic Characterization Reveals That MMP-3 Correlates With Bronchiolitis Obliterans Syndrome Following Allogeneic Hematopoietic Cell and Lung Transplantation.

scientific article

Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease

scientific article published on May 2016

Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease

scientific article published on 6 October 2011

Role of cytokines in the pathophysiology of acute graft-versus-host disease (GVHD): are serum/plasma cytokines potential biomarkers for diagnosis of acute GVHD following allogeneic hematopoietic cell transplantation (Allo-HCT)?

scientific article published on May 2012

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease

scientific article published on 07 March 2019

SNPs and prognosis of GvHD before HCT: any progress?

scientific article published on 12 October 2015

ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death

scientific article published on August 2013

ST2 as checkpoint target for colorectal cancer immunotherapy

scientific article published on 07 May 2020

ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease.

scientific article

ST2/MyD88 Deficiency Protects Mice against Acute Graft-versus-Host Disease and Spares Regulatory T Cells

scientific article published on 12 April 2019

Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma

scientific article published on 01 September 2003

Specific class I HLA supertypes but not HLA zygosity or expression are associated with outcomes following HLA-matched allogeneic hematopoietic cell transplant: HLA supertypes impact allogeneic HCT outcomes

scientific article published on 11 October 2020

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

scientific article published on 16 October 2017

Spontaneous Proliferation and Type 2 Cytokine Secretion by CD4+T Cells in Patients with Metastatic Melanoma Vaccinated with Antigen-Pulsed Dendritic Cells

article

TNF-inhibition with etanercept for graft-versus-host disease prevention in high-risk HCT: lower TNFR1 levels correlate with better outcomes

scientific article

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease

scientific article

The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases

scientific article

The search for drug-targetable diagnostic, prognostic and predictive biomarkers in chronic graft-versus-host disease

scientific article published on 19 April 2018

Translational research efforts in biomarkers and biology of early transplant-related complications

scientific article

Upper gastrointestinal acute graft--host disease adds minimal prognostic value in isolation or with other graft--host disease symptoms as currently diagnosed and treated

scholarly article by Sarah Nikiforow et al published October 2018 in Haematologica

Validation of genetic associations with acute GVHD and nonrelapse mortality in DISCOVeRY-BMT

scientific article published on 01 August 2019

Various forms of tissue damage and danger signals following hematopoietic stem-cell transplantation

scientific article

Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial

scientific article

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