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List of works by Sebastian Joyce

A Distinct Lung-Interstitium-Resident Memory CD8(+) T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection

scientific article published on 03 August 2016

A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence

scientific article

A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination

scientific article

A murine locus on chromosome 18 controls NKT cell homeostasis and Th cell differentiation

scientific article published in November 2003

AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells

scientific article published on 01 May 2019

Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype

scientific article published on 23 September 2015

Acute clearance of human metapneumovirus occurs independently of natural killer cells

scientific article

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on 08 October 2009

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on December 2009

Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood.

scientific article

Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural T(iNKT) cell receptor [corrected].

scientific article published on November 2003

Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL.

scientific article published in September 2003

Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease

scientific article published on 11 June 2015

CD1-restricted antigen presentation: an oily matter

scientific article

CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells

scientific article

CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences

scientific article published on 07 July 2008

CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection

scientific article

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4

scientific journal article

CD4 Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses

scientific article published on 11 July 2018

Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor

scientific article

Cell-Based Systems Biology Analysis of Human AS03-Adjuvanted H5N1 Avian Influenza Vaccine Responses: A Phase I Randomized Controlled Trial

scientific article

Characterization and Functional Analysis of Mouse Semi-invariant Natural T Cells

scientific article published on 3 April 2017

Characterization and functional analysis of mouse invariant natural T (iNKT) cells

scientific article published on 01 July 2006

Chronic rejection of murine cardiac allografts discordant at the H13 minor histocompatibility antigen correlates with the generation of the H13-specific CD8+ cytotoxic T cells

scientific article published on 01 July 2003

Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny

scientific article

Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections

scientific article

Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo

scientific article published on June 2008

Cutting edge: the minor histocompatibility antigen H60 peptide interacts with both H-2Kb and NKG2D.

scientific article published on April 2002

Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B.

scientific article published in April 2004

Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency

scholarly article

Discovering naturally processed antigenic determinants that confer protective T cell immunity

scientific article published on April 2013

Discovering protective CD8 T cell epitopes--no single immunologic property predicts it!

scientific article published on 06 February 2015

Distinct Roles of Dendritic Cells and B Cells in Va14Ja18 Natural T Cell Activation In Vivo

scientific article published on 01 April 2005

Distinct roles for signals relayed through the common cytokine receptor gamma chain and interleukin 7 receptor alpha chain in natural T cell development

scientific article

Duration of alloantigen presentation and avidity of T cell antigen recognition correlate with immunodominance of CTL response to minor histocompatibility antigens

scientific article published on June 2004

Eliciting Epitope-Specific CD8+ T Cell Response by Immunization with Microbial Protein Antigens Formulated with α-Galactosylceramide: Theory, Practice, and Protocols

scientific article published on January 2017

Fatty Acid-Mimetic Micelles for Dual Delivery of Antigens and Imidazoquinoline Adjuvants

scientific article published on 9 November 2016

Follicular B cell trafficking within the spleen actively restricts humoral immune responses

scientific article

Genetic Dissection of V 14J 18 Natural T Cell Number and Function in Autoimmune-Prone Mice

scientific article published on 01 June 2003

Glycolipid antigen induces long-term natural killer T cell anergy in mice

scientific article

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

scientific article published on 31 August 2006

Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection model

scientific article published on 05 August 2020

Histone Deacetylase 3 Is Required for Efficient T Cell Development

scientific article

IL-15 regulates homeostasis and terminal maturation of NKT cells

scientific article (publication date: 15 December 2011)

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD

scientific article published on 28 March 2008

Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells

scientific article

Identifying and Tracking Low-Frequency Virus-Specific TCR Clonotypes Using High-Throughput Sequencing

Immune recognition, response, and regulation: how T lymphocytes do it.

scientific article

Immunodominance of H60 is caused by an abnormally high precursor T cell pool directed against its unique minor histocompatibility antigen peptide

scientific article published on 01 November 2002

Immunology: TRIM5 does double duty.

scientific article

Immunoproteasomes edit tumors, which then escapes immune recognition

scientific article published on 3 November 2015

Immunoregulatory Role of CD1d in the Hydrocarbon Oil-Induced Model of Lupus Nephritis

scientific article published on 01 August 2003

Immunoregulatory defects of V alpha 24V+ beta 11+ NKT cells in development of Wegener's granulomatosis and relapsing polychondritis.

scientific article

Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine

scientific article

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

scientific article

Increase in hepatic NKT cells in leukocyte cell-derived chemotaxin 2-deficient mice contributes to severe concanavalin A-induced hepatitis

scientific article published in July 2004

Innate immunity: NKT cells in the spotlight

scientific article

Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences

scientific article

Invariant Natural Killer T Cells Trigger Adaptive Lymphocytes to Churn Up Bile

scientific article published on 01 May 2008

Lipid metabolism, atherogenesis and CD1-restricted antigen presentation

scientific article

Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum

scientific article published in January 2002

Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved

scientific journal article

Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms

scientific article published on 14 August 2018

Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells

scientific article published on 10 June 2015

Lung NKT cell commotion takes your breath away

scientific article published on 01 June 2008

Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways

scientific article published on June 2010

Mapping the orientation of an antigenic peptide bound in the antigen binding groove of H-2Kb using a monoclonal antibody.

scientific article published on August 1992

Mechanisms and Consequences of Antigen Presentation by CD1.

scientific article published on 9 September 2016

Minor histocompatibility antigens: presentation principles, recognition logic and the potential for a healing hand

scientific article published on August 2010

Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells

scientific article published on 04 October 2019

Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response

scientific article published on 21 October 2014

NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes

scientific article

NF-κB Protects NKT Cells from Tumor Necrosis Factor Receptor 1-induced Death.

scientific article

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

scientific article published on 01 April 2020

NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors

scientific article published on August 2011

Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective

scientific article published on 22 December 2017

Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

scientific article

Natural killer T cell-a cat o' nine lives!

scientific article

Natural killer T cells accelerate atherogenesis in mice

scientific article

Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.

scientific article

Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented

scientific journal article

Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells

scientific article published on 19 April 2016

Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

scientific article published on 01 July 2020

Point mutations in the beta chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I/peptide complex over a broad interface area

scientific article published on 01 July 1998

Poly(propylacrylic acid)-peptide nanoplexes as a platform for enhancing the immunogenicity of neoantigen cancer vaccines

scientific article published on 30 July 2018

Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigens

scientific article published on 13 May 2011

Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination

scientific article published on 15 May 2017

Quantitation of CD8(+) T-lymphocyte responses to multiple epitopes from simian virus 40 (SV40) large T antigen in C57BL/6 mice immunized with SV40, SV40 T-antigen-transformed cells, or vaccinia virus recombinants expressing full-length T antigen or

scientific article published on 01 August 2000

Quantitative and Qualitative Differences in Proatherogenic NKT Cells in Apolipoprotein E–Deficient Mice

scientific article published on 07 October 2004

Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids

scientific article published in September 2004

Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease

scientific article published on 22 August 2002

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

scientific journal article

Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1.

scientific article

Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication

scientific article published on 4 February 2015

Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses

scientific article published on 5 March 2013

Survivre et vivre: When iNKT cells met a Hippo

scientific article published on 01 June 2020

The H4b minor histocompatibility antigen is caused by a combination of genetically determined and posttranslational modifications

scientific article

The Hunt for iNKT Cell Antigens: α-Galactosidase-Deficient Mice to the Rescue?

scientific article published on August 27, 2010

The assembly of functional beta(2)-microglobulin-free MHC class I molecules that interact with peptides and CD8(+) T lymphocytes

scientific article published on July 2002

The natural killer T cell ligand alpha-galactosylceramide prevents or promotes pristane-induced lupus in mice

scientific article published on April 2005

The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion

scientific article

The role of invariant natural killer T cells in lupus and atherogenesis

scientific article

Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum

scientific article published on 01 March 1997

Viral acute lower respiratory infections impair CD8+ T cells through PD-1

scientific article

Viral evasion of antigen presentation: not just for peptides anymore

scientific article published in August 2006

Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules

scientific article published on December 2015

What one lipid giveth, another taketh away

scientific article published on 01 December 2019