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List of works by Samuel D Rabkin

A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS)

scientific article published on 28 June 2019

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

scientific article published on 6 March 2016

A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. ⬇️

scientific article

AI-21HIF-1A TARGETING IN AN ORTHOTOPIC XENOGRAFT MODEL THAT RECAPITULATES THE HYPOXIC MICROENVIRONMENT OF GLIOBLASTOMA.

scientific article

An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.

scientific article published on 23 May 2013

Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex

scientific article published in July 2003

Analysis of genetically engineered oncolytic herpes simplex viruses in human prostate cancer organotypic cultures.

scientific article published on December 2009

Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide

scientific article published on January 2007

Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas ⬇️

scientific article published on September 1, 1995

Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice

scientific article

Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma.

scientific article published on 13 September 2011

Biosynthesis of defective HSV DNA

Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models

scientific article published on 12 August 2017

Brain Tumor Therapy Using Genetically Engineered Replication-Competent Virus

article

CNS INDUCED NEUROGENIC CYSTITIS IS ASSOCIATED WITH BLADDER MAST CELL DEGRANULATION IN THE RAT

scientific article published on 01 September 2000

Cancer stem cell-like cells derived from malignant peripheral nerve sheath tumors

scientific article

Co-expression of two gene products in the CNS using double-cassette defective herpes simplex virus vectors.

scientific article published in April 1996

Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells

scientific article published on December 2008

Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models.

scientific article published on June 2013

Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine.

scientific article published in February 2001

Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models.

scientific article published on 29 March 2018

Combinatorial strategies for oncolytic herpes simplex virus therapy of brain tumors.

scientific article published on March 2013

Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy.

scientific article published in November 1999

Curing glioblastoma: oncolytic HSV-IL12 and checkpoint blockade

scientific article published on July 2017

Current Status of Gene Therapy for Brain Tumors∗

article

Current status of gene therapy for brain tumors.

scientific article

Defective Herpes Simplex Virus DNA: Circular and Circular-linear Molecules Resembling Rolling Circles

scientific article published on August 1, 1978

Designing Herpes Viruses as Oncolytics

scientific article

Development of Oncolytic Replication-Competent Herpes Simplex Virus Vectors

article

Directed evolution of adeno-associated virus for glioma cell transduction

scientific article published on 19 July 2009

Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.

scientific article

Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors.

scientific article published on November 2006

EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA

scientific article published on January 2015

Effect of acetylated and deacetylated 2-aminofluorene adducts on in vitro DNA synthesis ⬇️

scientific article published on December 1, 1982

Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.

scientific article published on January 2006

Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice.

scientific article published in October 1999

Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors ⬇️

scientific article published on February 15, 2012

Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector

scientific article published in October 2006

Electron microscopy of branched HSV DNA molecules: Possible recombination intermediates

Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts

scientific article published on 5 October 2011

Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers.

scientific article

Experimental Therapy for Malignant Brain Tumors Using Genetically Engineered Herpes Simplex Virus Type 1

article published in 1996

Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma

scientific article published on September 2012

Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells.

scientific article published on October 1994

Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases

scientific article

GABA Synthesis in Astrocytes After Infection with Defective Herpes Simplex Virus Vectors Expressing Glutamic Acid Decarboxylase 65 or 67

Genetically distinct glioma stem-like cell xenografts established from paired glioblastoma samples harvested before and after molecularly targeted therapy

scientific article published in Scientific Reports

Glioblastoma Hypoxia Promotes Oncolytic HSV Replication in vitro and in vivo

Herpes simplex virus DNA polymerase, thymidine kinase and deoxyribonuclease activities in cells infected with wild type, ultraviolet-irradiated and defective virus ⬇️

scientific article published on January 1, 1979

Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics.

scientific article

Herpes simplex virus delivery to orthotopic rectal carcinoma results in an efficient and selective antitumor effect.

scientific article

Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors

scientific article published on 07 April 2009

Hypoxia enhances the replication of oncolytic herpes simplex virus

scientific article

Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication

scientific article

Immunovirotherapy for glioblastoma.

scientific article published on 14 November 2013

Immunovirotherapy for the treatment of glioblastoma.

scientific article published on January 2014

In Vitro Replication of Mutagen-Damaged DNA: Sites of Termination ⬇️

scientific article published on 01 January 1982

In vitro bypass of UV-induced lesions by Escherichia coli DNA polymerase I: specificity of nucleotide incorporation.

scientific article published on March 1983

Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470.

scientific article published in January 1995

Interactions between DNA polymerase and aminofluorene adducts that affect the recognition and possibly the mutagenicity of the lesions

scientific article published on 01 August 1982

Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain.

scientific article published in April 2005

Ionizing Radiation Does Not Alter the Antitumor Activity of Herpes Simplex Virus Vector G207 in Subcutaneous Tumor Models of Human and Murine Prostate Cancer ⬇️

scientific article published on September 1, 2001

MEK inhibition enhances oncolytic virus immunotherapy through increased tumor cell killing and T cell activation

scientific article published on 01 December 2018

MNGO-16ESTABLISHMENT OF A PATIENT - DERIVED ORTHOTOPIC MALIGNANT MENINGIOMA MODEL FOR THE DEVELOPMENT OF TARGETED THERAPY.

scientific article

Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

scientific article published on August 2017

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.

scientific article published on 7 November 2011

Modification of extracellular matrix enhances oncolytic adenovirus immunotherapy in glioblastoma

scientific article published on 30 November 2020

Molecular analysis of simian varicella virus DNA

scientific article published on October 1, 1992

Multi-parametric flow cytometry staining procedure for analyzing tumor-infiltrating immune cells following oncolytic herpes simplex virus immunotherapy in intracranial glioblastoma

scientific article published on 04 April 2019

Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model

scientific article published on 10 June 2013

Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors

scientific article published on 28 August 2012

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

scientific article published on 02 July 2019

New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting

scientific article

Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase ⬇️

scientific article published on October 30, 1998

Nucleoprotein complex formed between herpes simplex virus UL9 protein and the origin of DNA replication: inter- and intramolecular interactions

scientific article published on December 1991

Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy.

scientific article published on 10 October 2006

Oncolytic Herpes Simplex Virus (G207) Therapy

Oncolytic Herpes Simplex Virus Counteracts the Hypoxia-Induced Modulation of Glioblastoma Stem-Like Cells ⬇️

scientific article published on March 21, 2012

Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells

Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer.

scientific article published on 11 March 2010

Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma

scientific article published on 01 July 2018

Oncolytic herpes simplex virus interactions with the host immune system

scientific article

Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.

scientific article published on January 2006

Oncolytic herpes simplex virus therapy for peripheral nerve tumors.

scientific article published on 15 June 2007

Oncolytic herpes simplex virus treatment of metastatic breast cancer

scientific article

Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma

scientific article published on November 2005

Oncolytic herpes simplex virus vector therapy of breast cancer in C3(1)/SV40 T-antigen transgenic mice.

scientific article published on February 2005

Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing.

scientific article

Oncolytic herpes simplex virus vectors and chemotherapy: are combinatorial strategies more effective for cancer?

scientific article

Oncolytic herpes simplex virus vectors for cancer virotherapy

scientific article (publication date: December 2002)

Oncolytic herpes simplex virus vectors for the treatment of human breast cancer.

scientific article published in February 2005

Oncolytic virus immunotherapy induces immunogenic cell death and overcomes STING deficiency in melanoma

scientific article published on 07 April 2019

Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.

scientific article published on 15 December 2011

Oncolytic viruses and their application to cancer immunotherapy

scientific article published on April 2014

Oncolytic viruses on the cusp of success?: proceedings of the 9th International Conference on Oncolytic Virus Therapeutics

scientific article

Prospect and progress of oncolytic viruses for treating peripheral nerve sheath tumors.

scientific article published on 26 December 2015

RESTRICTION OF γ34.5-DELETED ONCOLYTIC HERPES SIMPLEX VIRUS REPLICATION IN GLIOBLASTOMA STEM-LIKE CELLS.

scientific article

Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma

scientific article published on March 2017

Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes

scientific article

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

scientific article published on 10 April 2014

Replication of HSV-1 DNA: Isolation of a subnuclear DNA synthesizing fraction

Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma.

scientific article

Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma

scientific article published on 12 September 2014

Specific Patterns of Defective HSV-1 Gene Transfer in the Adult Central Nervous System: Implications for Gene Targeting

article

Systemic oncolytic herpes virus therapy of poorly immunogenic prostate cancer metastatic to lung

scientific article published on May 2006

Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses

scientific article published in October 2007

Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment

scientific article published on July 2015

The discovery and development of oncolytic viruses: are they the future of cancer immunotherapy?

scientific article published on 24 November 2020

The role of DNA polymerase in base substitution mutagenesis on non-instructional templates.

scientific article published on August 1982

Therapeutic Efficacy of G207 in a Novel Peripheral Nerve Sheath Tumor Model

Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model.

scientific article published in May 2001

Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma

scientific article published on 15 January 2016

Treatment of Human Breast Cancer in a Brain Metastatic Model by G207, a Replication-Competent Multimutated Herpes Simplex Virus 1 ⬇️

scientific article published on October 10, 1998

Treatment of Schwannomas with an Oncolytic Recombinant Herpes Simplex Virus in Murine Models of Neurofibromatosis Type 2

Treatment of human hepatocellular carcinoma by the oncolytic herpes simplex virus G47delta

scientific article

Treatment of human thyroid carcinoma cells with the g47delta oncolytic herpes simplex virus

scientific article

Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta.

scientific article published on 16 February 2007

Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus.

scientific article

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

scientific article

Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects

scientific article published on April 2008

Triple threat to cancer: rationale for combining oncolytic viruses, MEK inhibitors, and immune checkpoint blockade

scientific article published on 03 February 2019

Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor.

scientific article published in October 2000

Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus.

scientific article published in December 2000

Viral vectors as therapeutic agents for glioblastoma.

scientific article

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