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List of works by Irma Airoldi

Absence of IL-12Rβ2 in CD33+CD38+ pediatric acute myeloid leukemia cells favours progression in NOD/SCID/IL2RγC-deficient mice ⬇️

scientific article published on August 16, 2011

Anti-leukemic properties of IL-12, IL-23 and IL-27: differences and similarities in the control of pediatric B acute lymphoblastic leukemia.

scientific article published on 15 December 2011

CXCR5 may be involved in the attraction of human metastatic neuroblastoma cells to the bone marrow.

scientific article published on 5 September 2007

Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo.

scientific article

Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target.

scientific article published on 12 May 2008

Cytokines and microRNA in pediatric B-acute lymphoblastic leukemia ⬇️

scientific article published on July 20, 2011

Cytokines as anti-angiogenic agents in haematological malignancies.

scientific article

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.

scientific article published on 6 June 2016

Differential DNA binding properties of three human homeodomain proteins

scientific article

Direct inhibition of human acute myeloid leukemia cell growth by IL-12.

scientific article published on 10 August 2010

Endogenous IL-12 triggers an antiangiogenic program in melanoma cells.

scholarly article

Engrafted maternal T cells in human severe combined immunodeficiency: evidence for a TH2 phenotype and a potential role of apoptosis on the restriction of T-cell receptor variable beta repertoire

scientific article published on 01 January 1998

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells.

scientific article published on 18 July 2017

Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L.

scientific article published on May 2003

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

scientific article published on 17 June 2016

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

scientific article published on 23 November 2010

Heterogeneous expression of interleukin-18 and its receptor in B-cell lymphoproliferative disorders deriving from naive, germinal center, and memory B lymphocytes.

scientific article

Human TCRγδ+ T cells represent a novel target for IL-27 activity.

scientific article published on June 2012

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

scientific article published on 24 January 2013

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

scientific article

IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-γ release by autologous NK cells

scientific article published on 10 March 2014

IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation

scientific article

IL-27 induces the expression of IDO and PD-L1 in human cancer cells

scientific article published on 9 December 2015

IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma.

scientific article published on 29 October 2015

Immunogenicity of human neuroblastoma.

scientific article

Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells ⬇️

scientific article published on July 29, 2010

Interleukin-27 and interleukin-23 modulate human plasmacell functions ⬇️

scientific article published on February 17, 2011

Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model ⬇️

scientific article published on June 24, 2011

Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice.

scientific article published on March 2012

Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer

scientific article published on February 2015

Interleukin-30 Promotes Breast Cancer Growth and Progression

scientific article published on 22 August 2016

Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage.

scientific article

Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy

scientific article published on 04 August 2005

Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression

scientific article

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence.

scientific article published in February 2018

Novel Insights into the Role of Interleukin-27 and Interleukin-23 in Human Malignant and Normal Plasma Cells ⬇️

scientific article published on August 31, 2011

Regulation of angiostatic chemokines driven by IL-12 and IL-27 in human tumors ⬇️

scientific article published on July 12, 2011

SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression.

scientific article published on July 2015

SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker of lymph node metastasis.

scientific article published on 27 October 2015

Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells

scientific article published on 01 April 2000

The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies.

scientific article

The IL-18 antagonist IL-18-binding protein is produced in the human ovarian cancer microenvironment

scientific article published on 19 July 2013

The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells.

scientific article published on 11 December 2015

The antitumor potential of Interleukin-27 in prostate cancer

scientific article

The enigmatic role of interleukin-12 in the pathogenesis of Sjögren's syndrome: comment on the article by Vosters et al

scientific article published on 01 July 2010

Tumor necrosis factor (TNF) enhances the locomotion of low-density human tonsillar B lymphocytes through the selective triggering of type II receptor

scientific article published on 01 April 1997

Tumor-associated macrophages: from cancer supporters to tumoricidal effectors

scientific article published on 01 July 2012

Ultrastructural and functional studies of the interaction between IL-12 and IL-2 for the generation of lymphokine-activated killer cells

scientific article published on 01 December 1999

Zoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor.

scientific article published on 27 September 2016

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes

scientific article published on 22 January 2015

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