List of works - Yunjeong Kim

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

scientific article published on 03 August 2020

Anti-norovirus therapeutics: a patent review (2010-2015).

scientific article published on 16 February 2016

Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors

article

Backbone and side-chain ¹H, ¹⁵N, and ¹³C resonance assignments of Norwalk virus protease.

scientific article published on 8 June 2011

Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1.

scholarly article

Biodegradable nanogels for oral delivery of interferon for norovirus infection

scientific article

Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.

scientific article

Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses.

scientific article

Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway.

scientific article

Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.

scientific article published on 15 May 2015

Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay

scientific article

Characterization of group C rotaviruses associated with diarrhea outbreaks in feeder pigs

scientific article

Comparisons of nucleotide and deduced amino acid sequences of NSP4 genes of virulent and attenuated pairs of group A and C rotaviruses.

scientific article published in January 1999

Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.

scientific article published on 11 May 2016

Cyclosulfamide-based derivatives as inhibitors of noroviruses

scientific article published on 20 October 2011

Design and synthesis of inhibitors of noroviruses by scaffold hopping ⬇️

scientific article published on August 22, 2011

Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.

scientific article published on 3 July 2017

Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors

scientific article published on 30 September 2013

Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.

scientific article

Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease.

scientific article

Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis.

scientific article published on September 2017

Endosomal acidification and cathepsin L activity is required for calicivirus replication.

scientific article

Fexaramine as an entry blocker for feline caliciviruses.

scientific article published on 15 February 2018

Inhibition of influenza virus replication by plant-derived isoquercetin

scientific article published on 6 September 2010

Inhibition of noroviruses by piperazine derivatives ⬇️

scientific article published on November 15, 2011

Inhibitory Effects of Bile Acids and Synthetic Farnesoid X Receptor Agonists on Rotavirus Replication ⬇️

scientific article published on September 28, 2011

Lactogenic antibody responses in cows vaccinated with recombinant bovine rotavirus-like particles (VLPs) of two serotypes or inactivated bovine rotavirus vaccines

scientific article published on 01 January 2002

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.

scientific article published on 16 May 2013

Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection

scientific article published on January 2004

Novel triacsin C analogs as potential antivirals against rotavirus infections.

scientific article published on 11 February 2012

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease

scientific article

Potent inhibition of Norwalk virus by cyclic sulfamide derivatives ⬇️

scientific article published on August 27, 2011

Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides.

scientific article

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles ⬇️

scientific article published on May 26, 2012

Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.

scientific article published on 22 August 2013

Potent norovirus inhibitors based on the acyclic sulfamide scaffold ⬇️

scientific article published on 02 February 2012

Recent Advances in the Discovery of Norovirus Therapeutics

scientific article published on 10 August 2015

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.

scientific article

SARS-CoV-2 Omicron (B.1.1.529) Infection of Wild White-Tailed Deer in New York City

scientific article published in 2022

Structural and dynamics characterization of norovirus protease

scientific article

Structural and inhibitor studies of norovirus 3C-like proteases

scientific article published on 17 September 2013

Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.

scientific article published on 25 April 2016

Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.

scientific article

Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies

scientific article published on 19 March 2015

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

scientific article published on 6 March 2018

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.

scientific article published on 6 December 2017

Syntheses of 3-[(Alkylamino)methylene]-6-methylpyridine-2,4(1H,3H)-diones, 3-Substituted 7-Methyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione Fluorescence Probes, and Tetrahydro-1H,9H-2,10-dioxa-9-azaanthracen-1-ones.

scientific article

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds.

scientific article

Synthesis and antiviral activity of substituted quercetins ⬇️

scientific article published on November 6, 2011

The crucial role of bile acids in the entry of porcine enteric calicivirus

scientific article

The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.

scientific article

Trypsin-independent porcine epidemic diarrhea virus US strain with altered virus entry mechanism.

scientific article published on 25 November 2017

List of works by Yunjeong Kim

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice

Anti-norovirus therapeutics: a patent review (2010-2015).

Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors

Backbone and side-chain ¹H, ¹⁵N, and ¹³C resonance assignments of Norwalk virus protease.

Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1.

Biodegradable nanogels for oral delivery of interferon for norovirus infection

Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.

Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses.

Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway.

Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.

Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay

Characterization of group C rotaviruses associated with diarrhea outbreaks in feeder pigs

Comparisons of nucleotide and deduced amino acid sequences of NSP4 genes of virulent and attenuated pairs of group A and C rotaviruses.

Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.

Cyclosulfamide-based derivatives as inhibitors of noroviruses

Design and synthesis of inhibitors of noroviruses by scaffold hopping ⬇️

Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.

Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors

Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.

Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease.

Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis.

Endosomal acidification and cathepsin L activity is required for calicivirus replication.

Fexaramine as an entry blocker for feline caliciviruses.

Inhibition of influenza virus replication by plant-derived isoquercetin

Inhibition of noroviruses by piperazine derivatives ⬇️

Inhibitory Effects of Bile Acids and Synthetic Farnesoid X Receptor Agonists on Rotavirus Replication ⬇️

Lactogenic antibody responses in cows vaccinated with recombinant bovine rotavirus-like particles (VLPs) of two serotypes or inactivated bovine rotavirus vaccines

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.

Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection

Novel triacsin C analogs as potential antivirals against rotavirus infections.

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease

Potent inhibition of Norwalk virus by cyclic sulfamide derivatives ⬇️

Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides.

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles ⬇️

Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.

Potent norovirus inhibitors based on the acyclic sulfamide scaffold ⬇️

Recent Advances in the Discovery of Norovirus Therapeutics

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.

SARS-CoV-2 Omicron (B.1.1.529) Infection of Wild White-Tailed Deer in New York City

Structural and dynamics characterization of norovirus protease

Structural and inhibitor studies of norovirus 3C-like proteases

Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.

Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.

Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.

Syntheses of 3-[(Alkylamino)methylene]-6-methylpyridine-2,4(1H,3H)-diones, 3-Substituted 7-Methyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione Fluorescence Probes, and Tetrahydro-1H,9H-2,10-dioxa-9-azaanthracen-1-ones.

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds.

Synthesis and antiviral activity of substituted quercetins ⬇️

The crucial role of bile acids in the entry of porcine enteric calicivirus

The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.

Trypsin-independent porcine epidemic diarrhea virus US strain with altered virus entry mechanism.