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List of works by Jiří Vrba

Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry

scientific article published on 14 May 2012

Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells.

scientific article

Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine

scientific article published on 03 July 2007

Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells.

scientific article

Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity

scientific article published on 12 November 2015

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells.

scientific article

HDAC INHIBITORS SODIUM BUTYRATE AND SODIUM VALPROATE DO NOT AFFECT HUMAN NCOR1 AND NCOR2 GENE EXPRESSION IN HL-60 CELLS

scientific article published in September 2011

Identification of Human Sulfotransferases Active towards Silymarin Flavonolignans and Taxifolin

scientific article published on 12 August 2020

Induction of heme oxygenase-1 by Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells.

scientific article

Investigation of protein FTT1103 electroactivity using carbon and mercury electrodes. Surface-inhibition approach for disulfide oxidoreductases using silver amalgam powder

scientific article published on 2 May 2014

Isoquercitrin: pharmacology, toxicology, and metabolism

scientific article published on 27 March 2014

LC-MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model.

scientific article published on 14 August 2013

Metabolism of flavonolignans in human hepatocytes.

scientific article published on 30 January 2018

Metabolism of palmatine by human hepatocytes and recombinant cytochromes P450

scientific article published on 19 September 2014

Neutrophilic differentiation modulates the apoptotic response of HL-60 cells to sodium butyrate and sodium valproate.

scientific article published on January 2010

Novel flavonolignan hybrid antioxidants: From enzymatic preparation to molecular rationalization.

scientific article published on 26 December 2016

Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes.

scientific article published on 27 February 2014

Protective effect of isoquercitrin against acute dextran sulfate sodium-induced rat colitis depends on the severity of tissue damage.

scientific article published on 19 September 2016

Protopine and allocryptopine increase mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR

scientific article

Quercetin, quercetin glycosides and taxifolin differ in their ability to induce AhR activation and CYP1A1 expression in HepG2 cells.

scientific article published on 15 March 2012

Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues.

scientific article published in August 2005

Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism.

scientific article

Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

scientific article published on 21 October 2016

Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin.

scientific article published on 29 July 2015

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