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List of works by John R Bradley

"Cytosolic" phospholipase A2 is in the nucleus of subconfluent endothelial cells but confined to the cytoplasm of confluent endothelial cells and redistributes to the nuclear envelope and cell junctions upon histamine stimulation

scientific article published on 01 March 1996

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

scientific article

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss.

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

scientific article published on 12 February 2009

A rare life-threatening complication of an indwelling hemodialysis catheter.

scientific article published in January 2008

Abnormalities of the peripheral circulation in patients with chronic renal failure

scientific article published on 01 January 1988

Absence of hyperacute rejection and preservation of function in HDAF transgenic pig kidneys exposed to prolonged cold ischaemia

scientific article published on 01 August 2000

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils

scientific article published on 13 March 2006

Aortic valve replacement in chronic renal failure

scientific article published on 01 December 1985

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

scientific article published on 23 August 2009

Chickenpox in adult renal transplant recipients

scientific article published on 01 January 1987

Chronic kidney disease in primary care.

scientific article published in January 2007

Combined point of care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G Spike Variant

scientific article published on 01 September 2020

Comparison of vascular tone during combined haemodialysis with ultrafiltration and during ultrafiltration followed by haemodialysis: a possible mechanism for dialysis hypotension

scientific article

Cystic fibrosis pulmonary disease is not a contra-indication to live-related renal transplantation

scientific article published on 01 March 2005

DR3 signaling protects against cisplatin nephrotoxicity mediated by tumor necrosis factor.

scientific article

Disparate localization of 55-kd and 75-kd tumor necrosis factor receptors in human endothelial cells.

scientific article published on January 1995

Effects of prior fasting and of glucose availability on fatty-acid-induced increases in oxygen consumption in the rat perfused liver.

scientific article published in January 1982

Endothelial cell activation in patients with systemic vasculitis

scientific article published on 01 December 1994

Expression of tumor necrosis factor receptors in normal kidney and rejecting renal transplants

scientific article published on 01 November 2001

F.5. Cell-specific CD25 Expression is Determined by Type 1 Diabetes Associated IL2RA Haplotypes

Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells

scientific article published on 01 June 1993

Germline selection shapes human mitochondrial DNA diversity

scientific article published on 23 May 2019

Growth of porcine kidneys in their native and xenograft environment

scientific article published on 01 May 2000

Histamine antagonizes tumor necrosis factor (TNF) signaling by stimulating TNF receptor shedding from the cell surface and Golgi storage pool

scientific article published on 19 March 2003

Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the normal spatial organization of endothelial cell adhesion molecules.

scientific article published on September 1995

Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells

scientific article

In vitro self-assembly of human pericyte-supported endothelial microvessels in three-dimensional coculture: a simple model for interrogating endothelial-pericyte interactions.

scientific article published on 10 July 2013

Light chains and the kidney.

scientific article

Long-term survival in haemodialysis patients

scientific article published on 01 February 1987

Maintenance triple immunosuppression with cyclosporin A, mycophenolate sodium and steroids allows prolonged survival of primate recipients of hDAF porcine renal xenografts.

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Osteoclastic tartrate-resistant acid phosphatase (Acp 5): its localization to dendritic cells and diverse murine tissues

scientific article published on 01 February 2000

PHASE I STUDY OF AN ENGINEERED AGLYCOSYLATED HUMANIZED CD3 ANTIBODY IN RENAL TRANSPLANT REJECTION1

scientific article published on 01 December 1999

Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study

scientific article published on 27 January 2025

Physiological aspects of pig-to-primate renal xenotransplantation

scientific article published on 01 October 2001

Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study

scientific article published on 15 July 2020

Points: Paracetamol overdose as a cause of non-A non-B hepatitis.

scientific article published in February 1984

Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction

scientific article published on 23 September 2024

Prolonged cytokine exposure causes a dynamic redistribution of endothelial cell adhesion molecules to intercellular junctions

scientific article published on 01 October 1996

Radionuclide method for evaluating the performance of hemodialysis in vivo.

scientific article published in February 2005

Recent advances in the molecular basis of TNF signal transduction.

scientific article

Regional differences in the provision of adult renal dialysis services in the UK.

scientific article published in March 2005

Renal transplantation in Waldenström's macroglobulinaemia.

scientific article published on January 1988

Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model.

scientific article published on 3 November 2011

SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion

Student-constructed hydraulic and mechanical models for learning fundamentals of pharmacokinetics [proceedings] ⬇️

scientific article published on November 1, 1979

TL1A both promotes and protects from renal inflammation and injury

scientific article published on 20 February 2008

TNF receptors differentially signal and are differentially expressed and regulated in the human heart.

scientific article

TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1

scientific article

TNF-mediated inflammatory disease.

scientific article published on January 2008

TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury

scientific article

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

scientific article published on 13 January 2017

Targeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells

scientific article

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

scientific article

The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety

scientific article published on 24 October 2019

The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide

scientific article published on 01 July 1995

The N-terminal domains target TNF receptor-associated factor-2 to the nucleus and display transcriptional regulatory activity ⬇️

scientific article published on July 1, 1998

The Role of Tumor Necrosis Factor-α Converting Enzyme in Renal Transplant Rejection ⬇️

scientific article published on September 22, 2010

The bronze kidney: membranous glomerulonephritis associated with iron overload

scientific article published on 16 February 2015

The vascular endothelium in septic shock.

scientific article

Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.

scientific article published on 29 April 2004

Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

scientific article published on 14 December 2020

Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis

scientific article published on 30 June 2016

Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage.

scientific article published on August 1999

Tumor necrosis factor is delivered to mitochondria where a tumor necrosis factor-binding protein is localized

scientific article published on 01 December 1998

Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma

scientific article published on 16 March 2016

Tumor necrosis factor receptor expression and signaling in renal cell carcinoma

scientific article

Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II.

scientific article published on December 1998

Tumour necrosis factor and cancer

scientific article published on 01 July 2013

Tumour necrosis factor in infectious disease.

scientific article published on June 2013

Tumour necrosis factor is trafficked to a mitochondrial tumour necrosis factor binding protein

scientific article published on 01 November 1998

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