List of works - Andrew McGuire

An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.

scientific article published in April 2018

Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.

scientific article published on 16 April 2018

Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses

scientific article published on 25 July 2019

Cex1p facilitates Rna1p-mediated dissociation of the Los1p-tRNA-Gsp1p-GTP export complex.

scientific article

Cex1p is a novel cytoplasmic component of the Saccharomyces cerevisiae nuclear tRNA export machinery

scientific article

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

scientific article published on 28 August 2017

Designed proteins assemble antibodies into modular nanocages

scientific article published on 01 December 2020

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

scientific article published on 25 July 2019

Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors

scientific article

Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.

scientific article published on 18 December 2013

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

scientific article published on 25 March 2013

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

article

Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections.

scientific article published in November 2017

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

scientific article

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

scientific article published on 11 April 2019

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

scientific article published on 29 May 2019

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

scientific article

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

scientific article published on September 2016

Live rubella vectors can express native HIV envelope glycoproteins targeted by broadly neutralizing antibodies and prime the immune response to an envelope protein boost

scientific article published on 20 July 2018

Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses

scientific article

Nutrient stress does not cause retrograde transport of cytoplasmic tRNA to the nucleus in evolutionarily diverse organisms.

scientific article

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

scientific article

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

scientific article

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

scientific article published on 24 February 2016

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

scientific article published in December 2017

Structural basis for germline antibody recognition of HIV-1 immunogens

scientific article published on 21 March 2016

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

scientific article published on 27 October 2020

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

scientific article published on 11 April 2022

Structural modeling identified the tRNA-binding domain of Utp8p, an essential nucleolar component of the nuclear tRNA export machinery of Saccharomyces cerevisiae.

scientific article

Targeting broadly neutralizing antibody precursors: a naïve approach to vaccine design

scientific article published on 01 July 2019

List of works by Andrew McGuire

An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.

Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.

Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses

Cex1p facilitates Rna1p-mediated dissociation of the Los1p-tRNA-Gsp1p-GTP export complex.

Cex1p is a novel cytoplasmic component of the Saccharomyces cerevisiae nuclear tRNA export machinery

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

Designed proteins assemble antibodies into modular nanocages

Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors

Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections.

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Live rubella vectors can express native HIV envelope glycoproteins targeted by broadly neutralizing antibodies and prime the immune response to an envelope protein boost

Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses

Nutrient stress does not cause retrograde transport of cytoplasmic tRNA to the nucleus in evolutionarily diverse organisms.

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

Structural basis for germline antibody recognition of HIV-1 immunogens

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

Structural modeling identified the tRNA-binding domain of Utp8p, an essential nucleolar component of the nuclear tRNA export machinery of Saccharomyces cerevisiae.

Targeting broadly neutralizing antibody precursors: a naïve approach to vaccine design