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List of works by Wouter N Leonhard

Altered Hippo signalling in polycystic kidney disease.

scientific article

Common regulatory elements in the polycystic kidney disease 1 and 2 promoter regions

scientific article published on 01 May 2005

Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.

scientific article published on 23 February 2011

Cyst expansion and regression in a mouse model of polycystic kidney disease

scientific article published on 06 March 2013

Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells ⬇️

scientific article published on January 1, 2002

Dose-dependent effects of sirolimus on mTOR signaling and polycystic kidney disease

scientific article published on 16 February 2012

Elevated TGFbeta-Smad signalling in experimental Pkd1 models and human patients with polycystic kidney disease

scientific article published on 01 September 2010

Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2.

scientific article published on 6 February 2017

High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease

Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.

scientific article

Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease

scientific article published on 20 October 2004

Meta-analysis of polycystic kidney disease expression profiles defines strong involvement of injury repair processes.

scientific article

Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease

scientific article published on 3 March 2016

Quantification of Cre-mediated recombination by a novel strategy reveals a stable extra-chromosomal deletion-circle in mice

scientific article

Rapid high-throughput analysis of DNaseI hypersensitive sites using a modified Multiplex Ligation-dependent Probe Amplification approach

scientific article published on 4 September 2009

STAT5 drives abnormal proliferation in autosomal dominant polycystic kidney disease

scientific article published on 16 January 2017

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease

scientific article published on 31 October 2014

Therapeutic potential of vasopressin V2 receptor antagonist in a mouse model for autosomal dominant polycystic kidney disease: optimal timing and dosing of the drug ⬇️

scientific article published on March 10, 2011

Transgenic mice expressing tamoxifen-inducible Cre for somatic gene modification in renal epithelial cells.

scientific article published in May 2006

Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.

scientific article published on 30 March 2015

Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context.

scientific article

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