List of works - Sudhesh Kumar

17Beta-estradiol and anti-estrogen ICI:compound 182,780 regulate expression of lipoprotein lipase and hormone-sensitive lipase in isolated subcutaneous abdominal adipocytes.

scientific article published in April 2003

A 6-month "self-monitoring" lifestyle modification with increased sunlight exposure modestly improves vitamin D status, lipid profile and glycemic status in overweight and obese Saudi adults with varying glycemic levels

scientific article

A burning mouth associated with the use of hormone replacement therapy

scientific article published in March 2005

A cluster randomized controlled trial of the effectiveness and cost-effectiveness of intermediate care clinics for diabetes (ICCD): study protocol for a randomized controlled trial

scientific article

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro

scientific article published on 16 March 2011

Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus

scientific article published on 9 January 2007

Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum.

scientific article

Adiponectin is a candidate marker of metabolic syndrome in obese children and adolescents

scientific article

Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: the influence of circulating adiponectin

scientific article

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference

scientific article

Association of simple anthropometric measures of obesity with visceral fat and the metabolic syndrome in male Caucasian and Indo-Asian subjects.

scientific article

Avoidance of unhealthy fattening: a longstanding proposal

scientific article published on 19 October 2006

Can self-reported height and weight be relied upon?

scientific article published on 7 October 2011

Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies

scientific article published on 15 April 2009

Circadian gene variants and susceptibility to type 2 diabetes: a pilot study

scientific article (publication date: 2012)

Colonic fermentation--more than meets the nose

scientific article published on 26 May 2009

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population

scientific article

Comparison of 2 intensification regimens with rapid-acting insulin aspart in type 2 diabetes mellitus inadequately controlled by once-daily insulin detemir and oral antidiabetes drugs: the step-wise randomized study

scientific article published in September 2011

Dietary and lifestyle interventions for weight management in adults from minority ethnic/non-White groups: a systematic review.

scientific article

Dietary factors and type 2 diabetes in the Middle East: what is the evidence for an association?--a systematic review

scientific article

Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormone-sensitive lipase in human subcutaneous abdominal adipocytes

scientific article published on 01 July 2007

Dysregulation of plasma ghrelin in alcoholic cirrhosis

scientific article published on 23 February 2010

Editorial: Retinol binding protein 4 and pathogenesis of diabetes

scientific article published on 01 July 2007

Effect of the orlistat on serum endotoxin lipopolysaccharide and adipocytokines in South Asian individuals with impaired glucose tolerance.

scientific article

Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes

scientific article (publication date: 2011)

Effects of menopausal status on circulating calcitonin gene-related peptide and adipokines: implications for insulin resistance and cardiovascular risks.

scientific article

Elevated endotoxin levels in non-alcoholic fatty liver disease

scientific article

Empowering primary care to tackle the obesity epidemic: the Counterweight Programme

scientific article published on 01 August 2005

Engaging patients, clinicians and health funders in weight management: the Counterweight Programme

scientific article published on 27 November 2008

Essential role of fibroblast growth factor signaling in preadipoctye differentiation

scientific article published on 2 November 2004

Establishing abdominal height cut-offs and their association with conventional indices of obesity among Arab children and adolescents.

scientific article

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

scientific article published in July 2008

Evaluation of delivery of enhanced diabetes care to patients of South Asian ethnicity: the United Kingdom Asian Diabetes Study (UKADS).

scientific article published in December 2004

Evaluation of the clinical and cost effectiveness of intermediate care clinics for diabetes (ICCD): a multicentre cluster randomised controlled trial ⬇️

scientific article

Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM

scientific article published on 01 September 1996

Expression of calcitonin gene-related peptide, adrenomedullin, and receptor modifying proteins in human adipose tissue and alteration in their expression with menopause status

scientific article published on 01 November 2007

Fasting serum adiponectin concentration is reduced in Indo-Asian subjects and is related to HDL cholesterol.

scientific article published in March 2003

Frequency of latent autoimmune diabetes in adults in Asian patients diagnosed as type 2 diabetes in Birmingham, United Kingdom.

scientific article published in November 2003

Ghrelin and the differential regulation of des-acyl (DSG) and oct-anoyl ghrelin (OTG) in human adipose tissue (AT).

scientific article published on 23 June 2008

High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects

scientific article published on 30 December 2011

Higher prevalence of retinopathy in diabetic patients of South Asian ethnicity compared with white Europeans in the community: a cross-sectional study

scientific article

How strong is the association between abdominal obesity and the incidence of type 2 diabetes?

scientific article published on 28 June 2008

Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease

scientific article

Identification of brown adipose tissue using MR imaging in a human adult with histological and immunohistochemical confirmation.

scientific article published in January 2014

Improvement in glucose tolerance and beta-cell function in a patient with vitamin D deficiency during treatment with vitamin D.

scientific article published on June 1994

Increased vitamin D supplementation recommended during summer season in the gulf region: a counterintuitive seasonal effect in vitamin D levels in adult, overweight and obese Middle Eastern residents

scientific article published in March 2012

Insights into 'fermentonomics': evaluation of volatile organic compounds (VOCs) in human disease using an electronic 'e-nose'

scientific article published on 04 January 2011

Insulin increases angiotensinogen expression in human abdominal subcutaneous adipocytes

scientific article published on 01 November 2003

Insulin-mediated upregulation of the renin angiotensin system in human subcutaneous adipocytes is reduced by rosiglitazone

scientific article

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.

scientific article

Lack of association of angiotensin II type 1 receptor gene polymorphism with diabetic nephropathy in insulin-dependent diabetes mellitus

article

Laparoscopic greater curvature plication in morbidly obese women with type 2 diabetes: effects on glucose homeostasis, postprandial triglyceridemia and selected gut hormones

scientific article published in May 2014

Latent autoimmune diabetes in adults in a South Asian population of the U.K.

scientific article published on 18 September 2007

Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress

scientific article published on 31 May 2010

Long-term cost-effectiveness of weight management in primary care.

scientific article

Lower thresholds for diagnosis and management of obesity in British South Asians

article

Managing hyperglycemia in patients with Cushing's disease treated with pasireotide: medical expert recommendations

scientific article published on April 2014

Modest reversal of metabolic syndrome manifestations with vitamin D status correction: a 12-month prospective study

scientific article published on 8 November 2011

Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines.

scientific article

NFκB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFα.

scientific article published on 25 May 2013

Neonatal birth waist is positively predicted by second trimester maternal active ghrelin, a pro-appetite hormone, and negatively associated with third trimester maternal leptin, a pro-satiety hormone

scientific article published on 21 July 2014

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance

scientific article published on October 2006

Obesity and diabetes

scientific article published on 01 December 2009

Obesity in Different Ethnic Groups

Obesity; epiphenomenon or cause of metabolic syndrome?

scientific article published on June 2008

Parent-offspring transmission of adipocytokine levels and their associations with metabolic traits

scientific article

Pharmacological management of obesity

scientific article

Pharmacotherapy for overweight/obesity in ethnic minorities and White Caucasians: a systematic review and meta-analysis.

scientific article published on 03 December 2010

Plasma lipoprotein composition and cholesteryl ester transfer from high density lipoproteins to very low density and low density lipoproteins in patients with non-insulin-dependent diabetes mellitus

scientific article published on 01 February 1996

Potential therapies based on antidiabetic peptides

scientific article published on December 2007

Predictors of weight loss at 1 year after laparoscopic adjustable gastric banding and the role of presurgical quality of life.

scientific article

Premature cardiovascular events and mortality in south Asians with type 2 diabetes in the United Kingdom Asian Diabetes Study - effect of ethnicity on risk.

scientific article published in August 2010

Prevalence of microalbuminuria and hypertension in South Asians and white Europeans with type 2 diabetes: a report from the United Kingdom Asian Diabetes Study (UKADS)

scientific article published on 01 May 2006

Relationship of elevated urinary albumin excretion to components of the metabolic syndrome in non-insulin-dependent diabetes mellitus.

scientific article published in February 1998

Relationship of serum adiponectin and resistin to glucose intolerance and fat topography in South-Asians

scientific article

Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations

scientific article published on 25 February 2011

Resistin

scientific article

Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes

scientific article

Resistin, central obesity, and type 2 diabetes.

scientific article published in January 2002

Role of resistin in obesity, insulin resistance and Type II diabetes

scientific article

Secretion of neuropeptide Y in human adipose tissue and its role in maintenance of adipose tissue mass

scientific article published on 04 September 2007

Self-Reported Psychosocial Health in Obese Patients before and after Weight Loss.

scientific article

Self-reported disability in adults with severe obesity.

scientific article

Serum homocysteine concentration is related to diabetes mellitus, but not to coronary heart disease, in Saudi Arabians.

scientific article published in March 2002

Serum leptin and its relation to anthropometric measures of obesity in pre-diabetic Saudis

scientific article published on 7 July 2007

Serum resistin is associated with C-reactive protein & LDL cholesterol in type 2 diabetes and coronary artery disease in a Saudi population.

scientific article

Simultaneous Control of Hyperglycemia and Oxidative Stress Normalizes Endothelial Function in Type 1 Diabetes

scientific article published on 01 March 2007

Sleep duration and quality associated with obesity among Arab children

scientific article published on 4 June 2009

Tea and coffee consumption in relation to vitamin D and calcium levels in Saudi adolescents

scientific article

Telomere length attrition, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian males with type 2 diabetes mellitus

scientific article published in March 2012

The Counterweight programme: Prevalence of CVD risk factors by body mass index and the impact of 10% weight change

scientific article

The authors' reply: oestradiol concentrations are not elevated in obesity-associated hypogonadotrophic hypogonadism

scientific article published on 11 June 2013

The effects of adipose tissue and adipocytokines in human pregnancy ⬇️

scientific article published on September 1, 2010

The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes

scientific article published in March 2014

The impact of insulin resistance on woman's health and potential treatment options

scientific article published on September 2010

The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes

scientific article

The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

scientific article published on 2 September 2009

The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue.

scientific article published in May 2002

The role of maternal gut hormones in normal pregnancy: fasting plasma active glucagon-like peptide 1 level is a negative predictor of fetal abdomen circumference and maternal weight change

scientific article published in March 2010

Tumour necrosis factor-alpha exerts dual effects on human adipose leptin synthesis and release

scientific article published on 01 January 2000

Type 2 diabetes and cardiovascular risk in the UK south Asian community.

scientific article published on 18 July 2006

Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFκB and JNK in human abdominal subcutaneous adipocytes

scientific article

Vitamin D supplementation as an adjuvant therapy for patients with T2DM: an 18-month prospective interventional study

scientific article

Vitamin D supplementation in patients with diabetes mellitus type 2 on different therapeutic regimens: a one-year prospective study

scientific article published on 07 August 2013

Weight and glycaemic control in type 2 diabetes: what is the outcome of insulin initiation?

scientific article published in September 2011

List of works by Sudhesh Kumar

17Beta-estradiol and anti-estrogen ICI:compound 182,780 regulate expression of lipoprotein lipase and hormone-sensitive lipase in isolated subcutaneous abdominal adipocytes.

A 6-month "self-monitoring" lifestyle modification with increased sunlight exposure modestly improves vitamin D status, lipid profile and glycemic status in overweight and obese Saudi adults with varying glycemic levels

A burning mouth associated with the use of hormone replacement therapy

A cluster randomized controlled trial of the effectiveness and cost-effectiveness of intermediate care clinics for diabetes (ICCD): study protocol for a randomized controlled trial

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro

Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus

Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum.

Adiponectin is a candidate marker of metabolic syndrome in obese children and adolescents

Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: the influence of circulating adiponectin

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference

Association of simple anthropometric measures of obesity with visceral fat and the metabolic syndrome in male Caucasian and Indo-Asian subjects.

Avoidance of unhealthy fattening: a longstanding proposal

Can self-reported height and weight be relied upon?

Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies

Circadian gene variants and susceptibility to type 2 diabetes: a pilot study

Colonic fermentation--more than meets the nose

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population

Comparison of 2 intensification regimens with rapid-acting insulin aspart in type 2 diabetes mellitus inadequately controlled by once-daily insulin detemir and oral antidiabetes drugs: the step-wise randomized study

Dietary and lifestyle interventions for weight management in adults from minority ethnic/non-White groups: a systematic review.

Dietary factors and type 2 diabetes in the Middle East: what is the evidence for an association?--a systematic review

Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormone-sensitive lipase in human subcutaneous abdominal adipocytes

Dysregulation of plasma ghrelin in alcoholic cirrhosis

Editorial: Retinol binding protein 4 and pathogenesis of diabetes

Effect of the orlistat on serum endotoxin lipopolysaccharide and adipocytokines in South Asian individuals with impaired glucose tolerance.

Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes

Effects of menopausal status on circulating calcitonin gene-related peptide and adipokines: implications for insulin resistance and cardiovascular risks.

Elevated endotoxin levels in non-alcoholic fatty liver disease

Empowering primary care to tackle the obesity epidemic: the Counterweight Programme

Engaging patients, clinicians and health funders in weight management: the Counterweight Programme

Essential role of fibroblast growth factor signaling in preadipoctye differentiation

Establishing abdominal height cut-offs and their association with conventional indices of obesity among Arab children and adolescents.

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

Evaluation of delivery of enhanced diabetes care to patients of South Asian ethnicity: the United Kingdom Asian Diabetes Study (UKADS).

Evaluation of the clinical and cost effectiveness of intermediate care clinics for diabetes (ICCD): a multicentre cluster randomised controlled trial ⬇️

Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM

Expression of calcitonin gene-related peptide, adrenomedullin, and receptor modifying proteins in human adipose tissue and alteration in their expression with menopause status

Fasting serum adiponectin concentration is reduced in Indo-Asian subjects and is related to HDL cholesterol.

Frequency of latent autoimmune diabetes in adults in Asian patients diagnosed as type 2 diabetes in Birmingham, United Kingdom.

Ghrelin and the differential regulation of des-acyl (DSG) and oct-anoyl ghrelin (OTG) in human adipose tissue (AT).

High fat intake leads to acute postprandial exposure to circulating endotoxin in type 2 diabetic subjects

Higher prevalence of retinopathy in diabetic patients of South Asian ethnicity compared with white Europeans in the community: a cross-sectional study

How strong is the association between abdominal obesity and the incidence of type 2 diabetes?

Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease

Identification of brown adipose tissue using MR imaging in a human adult with histological and immunohistochemical confirmation.

Improvement in glucose tolerance and beta-cell function in a patient with vitamin D deficiency during treatment with vitamin D.

Increased vitamin D supplementation recommended during summer season in the gulf region: a counterintuitive seasonal effect in vitamin D levels in adult, overweight and obese Middle Eastern residents

Insights into 'fermentonomics': evaluation of volatile organic compounds (VOCs) in human disease using an electronic 'e-nose'

Insulin increases angiotensinogen expression in human abdominal subcutaneous adipocytes

Insulin-mediated upregulation of the renin angiotensin system in human subcutaneous adipocytes is reduced by rosiglitazone

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.

Lack of association of angiotensin II type 1 receptor gene polymorphism with diabetic nephropathy in insulin-dependent diabetes mellitus

Laparoscopic greater curvature plication in morbidly obese women with type 2 diabetes: effects on glucose homeostasis, postprandial triglyceridemia and selected gut hormones

Latent autoimmune diabetes in adults in a South Asian population of the U.K.

Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress

Long-term cost-effectiveness of weight management in primary care.

Lower thresholds for diagnosis and management of obesity in British South Asians

Managing hyperglycemia in patients with Cushing's disease treated with pasireotide: medical expert recommendations

Modest reversal of metabolic syndrome manifestations with vitamin D status correction: a 12-month prospective study

Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines.

NFκB as a potent regulator of inflammation in human adipose tissue, influenced by depot, adiposity, T2DM status, and TNFα.

Neonatal birth waist is positively predicted by second trimester maternal active ghrelin, a pro-appetite hormone, and negatively associated with third trimester maternal leptin, a pro-satiety hormone

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance

Obesity and diabetes

Obesity in Different Ethnic Groups

Obesity; epiphenomenon or cause of metabolic syndrome?

Parent-offspring transmission of adipocytokine levels and their associations with metabolic traits

Pharmacological management of obesity

Pharmacotherapy for overweight/obesity in ethnic minorities and White Caucasians: a systematic review and meta-analysis.

Plasma lipoprotein composition and cholesteryl ester transfer from high density lipoproteins to very low density and low density lipoproteins in patients with non-insulin-dependent diabetes mellitus

Potential therapies based on antidiabetic peptides

Predictors of weight loss at 1 year after laparoscopic adjustable gastric banding and the role of presurgical quality of life.

Premature cardiovascular events and mortality in south Asians with type 2 diabetes in the United Kingdom Asian Diabetes Study - effect of ethnicity on risk.

Prevalence of microalbuminuria and hypertension in South Asians and white Europeans with type 2 diabetes: a report from the United Kingdom Asian Diabetes Study (UKADS)

Relationship of elevated urinary albumin excretion to components of the metabolic syndrome in non-insulin-dependent diabetes mellitus.

Relationship of serum adiponectin and resistin to glucose intolerance and fat topography in South-Asians

Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations

Resistin

Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes

Resistin, central obesity, and type 2 diabetes.