List of works - Angelo Quattrini

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

scientific article published in April 2003

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons

scientific article

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

scientific article published in February 2008

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

scientific article

Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial.

scientific article published on 8 June 2016

Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy

scientific article published in November 2010

Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

scientific article (publication date: 18 June 2007)

In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice

scientific article published in March 2001

Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

scientific article

Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

scientific article

Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage

scientific journal article

Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.

scientific article

Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

TACE (ADAM17) inhibits Schwann cell myelination

scientific article

P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves

scientific article published on March 2000

Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

scientific article

Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

scientific article published on 23 June 2005

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.

scientific article

Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy

scientific journal article

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice

scientific article published on 01 February 2006

Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy.

scientific article published on 15 May 2010

Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination

scientific journal article

Loss of Mtmr2 phosphatase in Schwann cells but not in motor neurons causes Charcot-Marie-Tooth type 4B1 neuropathy with myelin outfoldings.

scientific article

Hypogonadotropic hypogonadism and peripheral neuropathy in Ebf2-null mice

scientific article published in January 2003

Peripheral neuropathy in hepatitis C virus infection with and without cryoglobulinaemia

scientific article (publication date: September 2003)

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

scientific article

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath

scientific article published on June 2008

iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF.

scientific article published in January 2013

A novel P0 glycoprotein transgene activates expression of lacZ in myelin-forming Schwann cells

scientific article published on May 1999

Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP.

scientific article published on December 2002

Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration.

scientific article published in July 2009

Role of integrins in the peripheral nervous system

scientific article

The mitochondrial protease AFG3L2 is essential for axonal development

scientific article published in March 2008

Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve

scientific article

Neurolupus is associated with anti-ribosomal P protein antibodies: An inception cohort study

scientific article published on 25 January 2009

Phenotypic clustering of lamin A/C mutations in neuromuscular patients.

scientific article published on 21 March 2007

Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP, in arthritic rats

scientific article published in July 2002

Genetic interaction between the m-AAA protease isoenzymes reveals novel roles in cerebellar degeneration

scientific article published on 16 March 2009

Vimentin regulates peripheral nerve myelination

scientific article published on 22 February 2012

Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons

scientific article published on September 2011

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination

scientific article published on 2 November 2014

CRYOGLOBULINAEMIC NEUROPATHY

scientific article published on 01 June 1988

Heterogeneity of autoantibodies in stiff-man syndrome

scientific article published on 01 July 1993

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

scientific article published in September 2007

Alpha6 beta4 and alpha6 beta1 integrins in astrocytomas and other CNS tumors

scientific article published in April 1996

Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model

scientific article published on 8 December 2014

Dominant LMNA mutations can cause combined muscular dystrophy and peripheral neuropathy.

scientific article

α6β1 and α7β1 integrins are required in Schwann cells to sort axons.

scientific article

Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.

scientific article published on 24 September 2012

Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice.

scientific article

List of works by Angelo Quattrini

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial.

Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy

Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice

Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage

Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.

Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

TACE (ADAM17) inhibits Schwann cell myelination

P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves

Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.

Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice

Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy.

Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination

Loss of Mtmr2 phosphatase in Schwann cells but not in motor neurons causes Charcot-Marie-Tooth type 4B1 neuropathy with myelin outfoldings.

Hypogonadotropic hypogonadism and peripheral neuropathy in Ebf2-null mice

Peripheral neuropathy in hepatitis C virus infection with and without cryoglobulinaemia

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath

iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF.

A novel P0 glycoprotein transgene activates expression of lacZ in myelin-forming Schwann cells

Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP.

Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration.

Role of integrins in the peripheral nervous system

The mitochondrial protease AFG3L2 is essential for axonal development

Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve

Neurolupus is associated with anti-ribosomal P protein antibodies: An inception cohort study

Phenotypic clustering of lamin A/C mutations in neuromuscular patients.

Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP, in arthritic rats

Genetic interaction between the m-AAA protease isoenzymes reveals novel roles in cerebellar degeneration

Vimentin regulates peripheral nerve myelination

Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination

CRYOGLOBULINAEMIC NEUROPATHY

Heterogeneity of autoantibodies in stiff-man syndrome

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

Alpha6 beta4 and alpha6 beta1 integrins in astrocytomas and other CNS tumors

Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model

Dominant LMNA mutations can cause combined muscular dystrophy and peripheral neuropathy.

α6β1 and α7β1 integrins are required in Schwann cells to sort axons.

Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity.

Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice.