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List of works by Theodore L Roth

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

journal article from 'bioRxiv' published in 2020

A burst in T cell receptor translation mediated by eIF3 interactions with T cell receptor mRNAs

scientific article published on 21 December 2019

A functional map of HIV-host interactions in primary human T cells

scientific article published on 01 April 2022

A large CRISPR-induced bystander mutation causes immune dysregulation

scientific article published on 18 February 2019

A rapid and simple method for DNA engineering using cycled ligation assembly

scientific article

CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions

scientific article published on 01 January 2019

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

scientific article published on 15 October 2020

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

scientific article published on 30 August 2017

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

scientific article published on 25 May 2018

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

scientific article published on 28 September 2020

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins

scientific article published on 31 March 2018

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

scientific article published on 15 November 2018

Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells

scientific article published on 01 November 2019

Inflammation and neuroprotection in traumatic brain injury

scientific article

Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells

scientific article published on 29 July 2019

Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device

scientific article published on 03 May 2018

Microglia development and function

scientific article

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

scientific article published on 03 August 2016

Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function

scientific article published on 10 June 2019

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

scientific article published on 09 December 2019

Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

scientific article published on 15 April 2020

Reprogramming human T cell function and specificity with non-viral genome targeting

scientific article published in Nature

Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1

scientific article (publication date: 7 July 2015)

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

scientific article published on 23 March 2021

Transcranial amelioration of inflammation and cell death after brain injury.

scientific article

Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system

scientific article (publication date: 2013)