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List of works by Sylvie Freeman

A comparison of FLAG-Ida and daunorubicin combined with clofarabine in high-risk acute myeloid leukaemia: data from the UK NCRI AML17 Trial

scientific article published on 06 June 2018

A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia.

scientific article published on 02 September 2016

A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow ⬇️

scientific article

An immunophenotypic pre-treatment predictor for poor response to induction chemotherapy in older acute myeloid leukaemia patients: blood frequency of CD34+ CD38 low blasts

scientific article published on 14 April 2015

Applicability and reproducibility of acute myeloid leukaemia stem cell assessment in a multi-centre setting

scientific article published on 02 April 2020

Assessment of Minimal Residual Disease in Standard-Risk AML.

scientific article

Assessment of minimal residual disease in acute myeloid leukemia

scientific article

Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

scientific article

Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes.

scientific article

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML

scientific article published on 19 March 2019

Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for "prime time"?

scientific article

Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for "prime time"?

scientific article published on 18 November 2014

Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31

scientific article (publication date: 30 April 1999)

Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia

scientific article

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

scientific article published on 04 July 2016

Identification of the CD33-related Siglec receptor, Siglec-5 (CD170), as a useful marker in both normal myelopoiesis and acute myeloid leukaemias

scientific article published on 01 November 2003

Induction response criteria in acute myeloid leukaemia: implications of a flow cytometric measurable residual disease negative test in refractory adults

scientific article published on 05 December 2018

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

scientific article

MRD evaluation of AML in clinical practice: are we there yet?

scientific article published on 01 December 2019

MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.

scientific article published on 22 August 2012

Measurable Residual Disease at Induction Redefines Partial Response in Acute Myeloid Leukemia and Stratifies Outcomes in Patients at Standard Risk Without NPM1 Mutations.

scientific article published on 30 March 2018

Minimal/measurable residual disease in AML: consensus document from ELN MRD Working Party.

scientific article published on 12 January 2018

Molecular MRD status and outcome after transplantation in NPM1-mutated AML

scientific article published on 01 February 2020

No evidence that CD33 splicing SNP impacts the response to GO in younger adults with AML treated on UK MRC/NCRI trials

scientific article

Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia

scientific article

Obesity is not associated with increased myelosuppression in patients receiving chemotherapy for breast cancer

scientific article published on 13 December 2006

Pretreatment haematological laboratory values predict for excessive myelosuppression in patients receiving adjuvant FEC chemotherapy for breast cancer.

scientific article published on 13 August 2008

Professor David Grimwade (1962-2016)

scientific article published on 16 January 2017

Prognostic relevance of treatment response measured by flow cytometric residual disease detection in older patients with acute myeloid leukemia

scientific article published on 23 September 2013

Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia

scientific article

Reduced CD38 expression on CD34+ cells as a diagnostic test in myelodysplastic syndromes

scientific article published on August 2009

Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia

scientific article published on 01 October 2019

Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation.

scientific article

T Cell Subset Enumeration and Weekend HIV Clinics: Reliable Performance of CD4 Cell Counts after 3 Days

article

The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2

scientific article

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