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List of works by Hisham Mehanna

A Q methodology study to investigate the experiences of head and neck cancer patients from diagnosis to 1 year

scientific article

A second national survey of health-related quality of life questionnaires in head and neck oncology

scientific article published on 30 April 2009

A systematic review and meta-analysis of the role of positron emission tomography in the follow up of head and neck squamous cell carcinoma following radiotherapy or chemoradiotherapy.

scientific article published on June 2008

Advanced head and neck cancer: is there a role for fluorodeoxyglucose PET/computed tomography?

scientific article published in January 2009

Association between loss of Y chromosome and poor prognosis in male head and neck squamous cell carcinoma

scientific article published on 23 December 2018

Biomarkers in dysplasia of the oral cavity: a systematic review.

scientific article published on 12 May 2009

Circulating Tumour Cell Biomarkers in Head and Neck Cancer: Current Progress and Future Prospects

scientific article published on 05 August 2019

Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma

scientific article published on 15 March 2018

Collagen Induces a More Proliferative, Migratory and Chemoresistant Phenotype in Head and Neck Cancer via DDR1

scientific article published on 09 November 2019

Concurrent cisplatin or cetuximab with radiotherapy for HPV-positive oropharyngeal cancer: Medical resource use, costs, and quality-adjusted survival from the De-ESCALaTE HPV trial

scientific article published on 30 November 2019

Consensus statement by otorhinolaryngologists and pathologists on the diagnosis and management of laryngeal dysplasia.

scientific article published on June 2010

Considerations for a head and neck smoking cessation support programme; A qualitative study of the challenges in quitting smoking after treatment for head and neck cancer

scientific article published on 06 June 2018

Correlation of currently used radiobiological parameters with local control and acute and late mucosal toxicity in randomised studies of altered fractionation for locally advanced head and neck cancer.

scientific article

Cost-effectiveness analysis of PET-CT-guided management for locally advanced head and neck cancer. ⬇️

scientific article published on 4 September 2017

Deterioration in quality-of-life of late (10-year) survivors of head and neck cancer.

scientific article published in June 2006

Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer

scientific article published on 10 June 2019

Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)

scientific article published on 24 May 2018

Dexamethasone reduces pain, vomiting and overall complications following tonsillectomy in adults: a systematic review and meta-analysis of randomised controlled trials.

scientific article

Differences in the recurrence and mortality outcomes rates of incidental and nonincidental papillary thyroid microcarcinoma: a systematic review and meta-analysis of 21 329 person-years of follow-up.

scientific article published on 14 May 2014

Early discharge following nasal pack removal: is it feasible?

scientific article published on 01 June 2002

Efficacy, outcomes, and complication rates of different surgical and nonsurgical treatment modalities for recurrent/residual oropharyngeal carcinoma: A systematic review and meta-analysis.

scientific article

Evidence for the approach to the diagnostic evaluation of squamous cell carcinoma occult primary tumors of the head and neck

scientific article published on 30 November 2018

External beam radiotherapy in differentiated thyroid carcinoma: A systematic review.

scientific article published on 03 September 2015

Facial palsy as the presenting complaint of perineural spread from cutaneous squamous cell carcinoma of the head and neck

scientific article published on 01 March 2007

Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer

scientific article published on 22 February 2018

Feasibility of recruitment to an oral dysplasia trial in the United Kingdom

scientific article published on 25 June 2012

Features and prognostic utility of biopsy in oral squamous cell carcinoma

scientific article published on 24 December 2015

Formation of an international intergroup to coordinate clinical trials in head and neck cancers: HNCIG.

scientific article published on 22 June 2017

Fungal laryngitis in immunocompetent patients.

scientific article published on May 2004

Geographic variation in human papillomavirus-related oropharyngeal cancer: Data from 4 multinational randomized trials

scientific article

HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

scientific article published on 28 January 2016

HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology.

scientific article published on 28 August 2016

Head and neck cancer--Part 1: Epidemiology, presentation, and prevention

scientific article

Head and neck cancer--Part 2: Treatment and prognostic factors.

scientific article published on 28 September 2010

Head and neck cancer-Part 2: Treatment and prognostic factors

article by Hisham Mehanna et al published April 2011 in Clinical Otolaryngology

Head and neck cancer-part 1: epidemiology, presentation, and preservation

scientific article published on February 2011

Human Papillomavirus (HPV) Vaccine Effectiveness and Potential Herd Immunity for Reducing Oncogenic Oropharyngeal HPV-16 Prevalence in the United Kingdom: A Cross-sectional Study

scientific article published on 01 September 2019

Hypofractionated accelerated radiotherapy with concurrent carboplatin for locally advanced squamous cell carcinoma of the head and neck

scientific article published on 21 September 2010

IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer.

scientific article

In Regard to Beadle and Anderson

scientific article published on 08 August 2018

International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV

scientific article published on 12 January 2019

Investigating the thyroid nodule.

scientific article published on 13 March 2009

Investigation of p16(INK4a) as a prognostic biomarker in oral epithelial dysplasia ⬇️

scientific article published on 26 December 2013

LIHNCS - Lugol's iodine in head and neck cancer surgery: a multicentre, randomised controlled trial assessing the effectiveness of Lugol's iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection m

scientific article published on 24 September 2013

Laryngeal dysplasia and narrow band imaging: Secondary analysis of published data supports the role in patient follow-up

scientific article published on 07 August 2018

Long-term survival outcomes in patients with surgically treated oropharyngeal cancer and defined human papilloma virus status

scientific article published on November 2016

Malignancy risk analysis in patients with inadequate fine needle aspiration cytology (FNAC) of the thyroid

scientific article

Management of advanced nodal disease in patients treated with primary chemoradiotherapy

scientific article published on 11 March 2016

Management of laryngeal dysplasia in the United Kingdom: a web-based questionnaire survey of current practice.

scientific article

Management of neck metastases in head and neck cancer: United Kingdom National Multidisciplinary Guidelines

scientific article published on May 2016

Modelling human papillomavirus biology in oropharyngeal keratinocytes

scientific article published on 01 May 2019

National audit of the management of peritonsillar abscess.

scientific article published on September 2002

Oncologic outcomes of transoral laser microsurgery for radiorecurrent laryngeal carcinoma: a systematic review and meta-analysis of English-language literature.

scientific article

Open conservation partial laryngectomy for laryngeal cancer: a systematic review of English language literature.

scientific article published on 20 July 2011

Oral Dysplasia: Biomarkers, Treatment, and Follow-up ⬇️

scientific article published on 01 April 2011

Oropharyngeal cancer - is it time to change management according to human papilloma virus status?

scientific article published on April 2012

Oropharyngeal cancer: United Kingdom National Multidisciplinary Guidelines.

scientific article published on May 2016

Oropharyngeal carcinoma related to human papillomavirus

scientific article published in the British Medical Journal

PET-CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer ⬇️

scientific article published on 23 March 2016

PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography-computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metasta ⬇️

scientific article

PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer

scientific article published on 28 August 2018

PTTG-Binding Factor (PBF) Is a Novel Regulator of the Thyroid Hormone Transporter MCT8 ⬇️

scientific article published on April 25, 2012

Patients' views on the utility of quality of life questionnaires in head and neck cancer: a randomised trial.

scientific article published in August 2006

Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol

scientific article published on 16 March 2020

Phase II, randomized, open-label study of durvalumab (MEDI4736) or tremelimumab monotherapy, or durvalumab + tremelimumab, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): CONDOR.

scientific article published on 4 November 2015

Postoperative Adjuvant Lapatinib and Concurrent Chemoradiotherapy Followed by Maintenance Lapatinib Monotherapy in High-Risk Patients With Resected Squamous Cell Carcinoma of the Head and Neck: A Phase III, Randomized, Double-Blind, Placebo-Controll

scientific article

Postoperative hypocalcemia--the difference a definition makes.

scientific article published on March 2010

Prediction of pharyngocutaneous fistulas after laryngectomy

scientific article published on 01 April 2007

Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer—systematic review and meta‐analysis of trends by time and region ⬇️

scientific article published on January 20, 2012

Pro-invasive Effect of Proto-oncogene PBF Is Modulated by an Interaction with Cortactin

scientific article published on 7 September 2016

Prognostic biomarkers of survival in oropharyngeal squamous cell carcinoma: systematic review and meta-analysis.

scientific article published on 20 September 2012

Prolonged treatment with vitamin D in postmenopausal women with primary hyperparathyroidism ⬇️

scientific article published on 08 June 2012

Provision of physiotherapy rehabilitation following neck dissection in the UK

scientific article published on 13 June 2018

Radiobiological modelling of the therapeutic ratio for the addition of synchronous chemotherapy to radiotherapy in locally advanced squamous cell carcinoma of the head and neck.

scientific article

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial

scientific article published in The Lancet

Randomised Phase II study of oral lapatinib combined with chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck: rationale for future randomised trials in human papilloma virus-negative disease.

scientific article published on 19 December 2012

Re-feeding syndrome in head and neck--prevention and management.

scientific article published on 05 July 2011

Reconstructive considerations in head and neck surgical oncology: United Kingdom National Multidisciplinary Guidelines

scientific article published on May 2016

Recurrence of Papillary Thyroid Cancer: A Systematic Appraisal of Risk Factors

scientific article published on 01 April 2022

Recurrent head and neck cancer: United Kingdom National Multidisciplinary Guidelines

scientific article published on May 2016

Refeeding syndrome--awareness, prevention and management.

scientific article published on 26 January 2009

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma

scientific article published on 27 August 2019

Resection of subsequent pulmonary metastases from treated head and neck squamous cell carcinoma: systematic review and meta-analysis.

scientific article published on June 2015

Revised Modelling of the Addition of Synchronous Chemotherapy to Radiotherapy in Squamous Cell Carcinoma of the Head and Neck-A Low α/β?

scientific article published on 13 June 2018

Revised radiobiological modelling of the contribution of synchronous chemotherapy to the rate of grades 3-4 mucositis in head and neck cancer

scientific article published on 9 July 2013

Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1-Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical Trial

scientific article published on 01 February 2019

Salivary gland swellings.

scientific article published on 23 October 2012

Salivary gland swellings.

scientific article published on February 2013

Should relatives watch resuscitation? Effect on relatives needs study.

scientific article published on August 1994

Surgical quality assurance in head and neck cancer trials: an EORTC Head and Neck Cancer Group position paper based on the EORTC 1420 'Best of' and 24954 'larynx preservation' study

scientific article published on 11 September 2018

Surgical trials in head & neck cancer – Are you serious? ⬇️

scientific article published on June 28, 2013

Surveillance of HPV-Positive Head and Neck Squamous Cell Carcinoma with Circulating and Salivary DNA Biomarkers

scientific article published on 01 January 2018

Suspending tonsillectomy: the effects on primary and secondary acute care in Scotland.

scientific article published in November 2004

TNM classification of malignant tumours 7th edition: what's new for head and neck?

scientific article published on 01 August 2010

Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. ⬇️

scientific article

The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review.

scientific article

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)

scientific article published on 15 July 2019

The association of psycho-social factors and survival in head and neck cancer.

scientific article

The binary oral dysplasia grading system: validity testing and suggested improvement.

scientific article published in January 2013

The case of the missing carotid artery--a well aimed knife!

scientific article published on 01 April 1998

The design of a multi-arm multi-stage (MAMS) phase III randomised controlled trial comparing alternative regimens for escalating (COMPARE) treatment of intermediate and high-risk oropharyngeal cancer with reflections on the complications of introduc

scientific article published on 16 November 2015

The impact of institutional clinical trial recruitment versus hospital volume on survival outcomes of patients with head and neck cancer: An analysis of the PET-NECK trial outcomes, UKCRN portfolio, and Hospital Episode Statistics (HES) in England

article

The risk and interval to malignancy of patients with laryngeal dysplasia; a systematic review of case series and meta‐analysis ⬇️

scientific article published on October 1, 2010

The role of PET CT in the management of advanced nodal head neck cancer post chemoradiotherapy

Toxicity Reduction in the Treatment of HPV Positive Oropharyngeal Cancer: Emerging Combined Modality Approaches

article

Transoral tongue base mucosectomy for the identification of the primary site in the work-up of cancers of unknown origin: Systematic review and meta-analysis

scientific article published on 06 March 2019

Treatment and follow-up of oral dysplasia - a systematic review and meta-analysis.

scientific article published on December 2009

Trends in head and neck cancers in England from 1995 to 2011 and projections up to 2025.

scientific article published on 22 January 2015

Unsupervised morphological segmentation of tissue compartments in histopathological images.

scientific article published on 30 November 2017

Update on De-intensification and Intensification Studies in HPV.

scientific article

Validation of tissue microarrays in oral epithelial dysplasia using a novel virtual-array technique.

scientific article

Variation in volume definition between UK head and neck oncologists treating oropharyngeal carcinoma

scientific article published on 04 August 2011

Who should be offered sperm banking for fertility preservation? A survey of UK oncologists and haematologists.

scientific article published on 27 October 2010

Why are head and neck cancer clinicians not measuring quality of life?

scientific article published on 17 May 2006

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