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List of works by Chris Bunce

1 alpha,25-Dihydroxyvitamin D3 promotes monocytopoiesis and suppresses granulocytopoiesis in cultures of normal human myeloid blast cells

scientific article published on 01 August 1994

A Combination of Calcium Ionophore and 12-O-Tetradecanoyl-Phorbol-13-Acetate (TPA) Stimulates the Growth of Purified Resting B Cells

scientific article published on 01 November 1985

A monoclonal antibody recognizes a human nuclear protein resembling Xenopus oocyte nucleoplasmin.

scientific article published on June 1987

A quick, simple and unbiased method to quantify C2C12 myogenic differentiation

scientific article published on September 1, 2011

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects

scientific article

Active multiple myeloma suppresses and typically eliminates coexisting MGUS.

scientific article

All-trans retinoic acid increases transgene expression in MSCV-transduced cells, via a mechanism that is retinoid receptor dependent but independent of cellular differentiation.

scientific article published in January 2005

Bezafibrate and medroxyprogesterone acetate in resistant and relapsed endemic Burkitt lymphoma in Malawi; an open-label, single-arm, phase 2 study (ISRCTN34303497).

scientific article

Bezafibrate and medroxyprogesterone acetate target resting and CD40L-stimulated primary marginal zone lymphoma and show promise in indolent B-cell non-Hodgkin lymphomas.

scientific article

Bistratene A Induces a Microtubule-Dependent Block in Cytokinesis and Altered Stathmin Expression in HL60 Cells

scientific article published on 01 June 1999

Cathepsin B synthesis by the HL60 promyelocytic cell line: effects of stimulating agents and anti-inflammatory compounds

scientific article published on 01 August 1986

Changes in insulin receptor expression in HL60 cells induced to differentiate towards neutrophils or monocytes

scientific article published on 01 November 1988

Changes in the levels of inositol lipids and phosphates during the differentiation of HL60 promyelocytic cells towards neutrophils or monocytes

scientific article published on 01 September 1991

Clofibric acid: a potential therapeutic agent in AML and MDS

scientific article published on 01 May 1999

Collagen or collagen-related peptide cause (Ca2+)i elevation and increased tyrosine phosphorylation in human megakaryocytes

scientific article published on 01 September 1999

Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML).

scientific article published on 13 January 2010

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia

scientific article

Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts.

scientific article published on February 1993

Correction: Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers.

scientific article

Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin.

scientific article

Defective erythropoiesis in myelodysplastic syndromes.

scientific article

Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids

scientific article published on 5 May 2015

Effect of Mg2+ on Na(+)-dependent inositol transport. Role for Mg2+ in etiology of diabetic complications.

scientific article published on January 1992

Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.

scientific article

Estrone potentiates myeloid cell differentiation

scientific article published in March 1999

Evaluation of solvent accessibility epitopes for different dehydrogenase inhibitors.

scientific article

Evidence that precursor cells of monocytes and B-lymphocytes are closely related

scientific article published on 01 October 1989

Expression of a nuclear envelope protein recognized by the monoclonal antibody BU31 in lung tumours: relationship to Ki-67 antigen expression

scientific article published on 01 June 1994

Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity.

scientific article

Fibrates and medroxyprogesterone acetate induce apoptosis of primary Burkitt's lymphoma cells and cell lines: potential for applying old drugs to a new disease.

scientific article published in March 2003

Growth of single HL60 cells in liquid culture: analysis of the influences of differentiative agents

scientific article published on 01 October 1996

Haemopoiesis: a lottery or genomic determinism?

scientific article published on 01 November 1991

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

scientific article published in October 2005

Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation.

scientific article published on 18 October 2010

Independent variations of myc amplification, inducibility, maturation, and proliferation states in HL60

scientific article published on 01 April 1988

Indomethacin potentiates the induction of HL60 differentiation to neutrophils, by retinoic acid and granulocyte colony-stimulating factor, and to monocytes, by vitamin D3.

scientific article published in April 1994

Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells

scientific article

Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells.

scientific article published on March 1995

Inositol lipids and phosphates in the differentiation of blood cells

scientific article published on 01 January 1990

Inositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells

scientific article published on January 1, 1992

Isolation and characterisation of dimethylsulphoxide resistant variants from the human promyeloid cell line HL60.

scientific article published on October 1983

Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells

scientific article

Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers

scientific article

Levels of inositol metabolites within normal myeloid blast cells and changes during their differentiation towards monocytes

scientific article published on 01 January 1992

Lineage determination during haemopoiesis

scientific article published on 01 January 1987

Lineage determination during haemopoiesis and classification of myelodysplastic disorders

scientific article published on 01 November 1986

Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance.

scientific article

Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential.

scientific article published in March 1995

Malonate as a ROS product is associated with pyruvate carboxylase activity in acute myeloid leukaemia cells.

scientific article published on 4 August 2016

Metabolic plasticity in CLL: adaptation to the hypoxic niche

scientific article published on 23 July 2015

Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines

scientific article

Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone

scientific article published on 17 December 2010

Optimized metabolite extraction from blood serum for 1H nuclear magnetic resonance spectroscopy

scientific article published on 05 February 2008

PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC.

scientific article published on 21 April 2005

Particular combinations of signals, by retinoic acid and 1 alpha, 25 dihydroxyvitamin D3, promote apoptosis of HL60 cells.

scientific article

Phorbol myristate acetate treatment of normal human myeloid blast cells promotes monopoiesis and inhibits granulopoiesis

scientific article published on 01 January 1990

Progenitor cells and classification of myelodysplastic and myeloproliferative disorders

scientific article published on 01 October 1985

Prostaglandins in muscle regeneration.

scientific article published on 04 December 2008

Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

scientific article published on 21 October 2011

Response comparison of multiple myeloma and monoclonal gammopathy of undetermined significance to the same anti-myeloma therapy: a retrospective cohort study. ⬇️

scientific article published on 13 November 2017

Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate

scientific article

Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells.

scientific article

Stochastic or ordered lineage commitment during hemopoiesis?

scientific article published on February 1987

Studies of human myeloid antigens using monoclonal antibodies and variant lines from the promyeloid cell line HL60

scientific article published on 01 November 1982

Studies of myelopoiesis using monoclonal antibodies and variant lines from the promyeloid cell line HL60

scientific article published on 01 January 1983

The 'known-knowns', and 'known-unknowns' of extracellular Nm23-H1/NDPK proteins.

scientific article published on 16 January 2018

The Haematopoietic Stem Cell Niche: New Insights into the Mechanisms Regulating Haematopoietic Stem Cell Behaviour ⬇️

scientific article published on October 30, 2011

The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks ⬇️

scientific article published in November 2017

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.

scientific article

The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

scientific article published in January 2003

The case for extracellular Nm23-H1 as a driver of acute myeloid leukaemia (AML) progression.

scientific article published on 15 August 2014

The development of cell lineages: a sequential model.

scientific article published on December 1988

Tracer-Based Metabolic NMR-Based Flux Analysis in a Leukaemia Cell Line.

scientific article published on 22 March 2016

Treatment of HL60 cells with various combinations of retinoids and 1 alpha,25 dihydroxyvitamin D3 results in differentiation towards neutrophils or monocytes or a failure to differentiate and apoptosis

scientific article published on 01 March 1995

Treatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches.

scientific article published on 23 September 2011

Variant cell lines from the human promyelocyte line HL60.

scientific article published on January 1982

Visfatin induces oxidative stress in differentiated C2C12 myotubes in an Akt- and MAPK-independent, NFkB-dependent manner.

scientific article

Vitamin D and hematopoiesis.

scientific article published on August 1997

Where now in elderly AML?

scientific article published on 13 February 2009

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