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List of works by Simon J Allison

A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes ⬇️

scientific article published on November 28, 2011

Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

scientific article

Anticancer metallohelices: nanomolar potency and high selectivity

scientific article published on 26 October 2015

Bis-picolinamide Ruthenium(III) Dihalide Complexes: Dichloride-to-Diiodide Exchange Generates Single trans Isomers with High Potency and Cancer Cell Selectivity ⬇️

scientific article

CBIO-33INVESTIGATING GLIOMA CELL PHENOTYPES WITH SMALL MOLECULES.

scientific article

CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells

scientific article

Correction for Shah et al., "A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes".

scientific article published on 28 July 2017

Cytotoxic hydrogen bridged ruthenium quinaldamide complexes showing induced cancer cell death by apoptosis ⬇️

scientific article published on 15 July 2016

Development and characterization of a microfluidic model of the tumour microenvironment

scientific article

Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors

scientific article published on January 2014

Hypoxia-Sensitive Metal β-Ketoiminato Complexes Showing Induced Single-Strand DNA Breaks and Cancer Cell Death by Apoptosis ⬇️

scientific article published on 8 June 2015

Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways

scientific article published on 12 May 2014

Increasing anti-cancer activity with longer tether lengths of group 9 Cp* complexes ⬇️

scientific article published on 29 February 2016

KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ⬇️

scientific article published on 01 August 2018

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

scientific article published on 9 September 2016

Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands ⬇️

scientific article published on 14 June 2017

RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3' Nuclease-resistant Mini-hairpin Structure.

scientific article published on 7 January 2014

RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumors.

scientific article published in November 2000

Revisiting Bromohexitols as a Novel Class of Microenvironment-Activated Prodrugs for Cancer Therapy

scientific article published on 26 November 2019

Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells

scientific article published on 03 July 2018

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.

scientific article

SIRT1, p53 and mitotic chromosomes.

scientific article published on 15 September 2011

Selective in vitro anti-cancer activity of non-alkylating minor groove binders

scientific article published on 18 July 2019

Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties

scientific article published on 23 June 2021

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