List of works - Václav Veverka

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

article published in the Proceedings of the National Academy of Sciences of the United States of America

Assignment of 1H, 13C, and 15N resonances of WT matrix protein and its R55F mutant from Mason-Pfizer monkey virus.

scientific article published in April 2005

Backbone resonance assignment of protease from Mason-Pfizer monkey virus.

scientific article published in July 2001

Backbone resonance assignments of human cytosolic dNT-1 nucleotidase

scientific article

Backbone resonance assignments of the outer membrane lipoprotein FrpD from Neisseria meningitidis

scientific article published on 09 December 2012

Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts

scientific article

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches ⬇️

scientific article

Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.

scientific article

Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation

scientific article

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases

scientific article

Corrigendum to "The Discovery, Engineering and Characterisation of a Highly Potent Anti-Human IL-13 Fab Fragment Designed for Administration by Inhalation" [J. Mol. Biol. 425 (2013), 577-593]

scientific article published on 05 April 2013

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

scientific article published on 11 December 2017

FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA

scientific article published in May 2022

Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

scientific article published on 24 August 2019

GTP-Dependent Formation of Multimeric G-Quadruplexes

scientific article published on 05 September 2019

High Resolution NMR-based Model for the Structure of a scFv-IL-1 Complex: POTENTIAL FOR NMR AS A KEY TOOL IN THERAPEUTIC ANTIBODY DESIGN AND DEVELOPMENT

scientific article

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.

scientific article

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

scientific article

Interaction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex

scientific article

Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5

scientific article published on 19 June 2013

Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers

scientific article published on 03 December 2020

Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5'(3')-deoxyribonucleotidase

scientific article

Letter to the Editor: Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6

scientific article published on 01 October 2004

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85

scientific article published on 09 June 2015

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

scientific article

NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4

scientific article published on 01 January 2006

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

scientific article

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

scientific article

Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.

scientific article

Ranking Power of the SQM/COSMO Scoring Function on Carbonic Anhydrase II-Inhibitor Complexes

scientific article published on 8 January 2018

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

scientific article published on 21 January 2016

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

scientific article

Resonance assignment and secondary structure determination of full length human Dickkopf 4 (hDkk4), a secreted, disulphide-rich Wnt inhibitor protein.

scientific article published on 11 May 2014

Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease

scientific article published on 13 January 2020

Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.

scientific article published on 05 July 2011

Structural Stability of Peptidic His-Containing Proton Wire in Solution and in the Adsorbed State

scientific article published on 05 June 2018

Structural basis for antimicrobial activity of lasiocepsin

scientific article

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

scientific article

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

scientific article published on 06 April 2020

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

scientific article published on 02 December 2020

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis

scientific article published on 13 January 2017

Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.

scientific article published on 14 August 2017

Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR

scientific article

Structural diversity in p160/CREB-binding protein coactivator complexes

scientific article published on 15 March 2006

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

scientific article

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.

scientific article published on 20 September 2016

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

scientific article published on 26 April 2013

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

scientific article

Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A

scientific article

Structure-activity study of macropin, a novel antimicrobial peptide from the venom of solitary bee Macropis fulvipes (Hymenoptera: Melittidae).

scientific article published on 11 March 2014

The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation.

scientific article

The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress

scientific article published on 17 October 2019

The statistical significance of selected sense-antisense peptide interactions.

scientific article

Three-dimensional structure of a monomeric form of a retroviral protease

scientific article

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

scientific article

¹⁵N, ¹³C and ¹H resonance assignments and secondary structure determination of a variable heavy domain of a heavy chain antibody.

scientific article

List of works by Václav Veverka

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Assignment of 1H, 13C, and 15N resonances of WT matrix protein and its R55F mutant from Mason-Pfizer monkey virus.

Backbone resonance assignment of protease from Mason-Pfizer monkey virus.

Backbone resonance assignments of human cytosolic dNT-1 nucleotidase

Backbone resonance assignments of the outer membrane lipoprotein FrpD from Neisseria meningitidis

Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches ⬇️

Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.

Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation

Conformationally constrained nucleoside phosphonic acids--potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases

Corrigendum to "The Discovery, Engineering and Characterisation of a Highly Potent Anti-Human IL-13 Fab Fragment Designed for Administration by Inhalation" [J. Mol. Biol. 425 (2013), 577-593]

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA

Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

GTP-Dependent Formation of Multimeric G-Quadruplexes

High Resolution NMR-based Model for the Structure of a scFv-IL-1 Complex: POTENTIAL FOR NMR AS A KEY TOOL IN THERAPEUTIC ANTIBODY DESIGN AND DEVELOPMENT

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

Interaction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex

Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5

Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers

Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5'(3')-deoxyribonucleotidase

Letter to the Editor: Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4

Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.

Ranking Power of the SQM/COSMO Scoring Function on Carbonic Anhydrase II-Inhibitor Complexes

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

Resonance assignment and secondary structure determination of full length human Dickkopf 4 (hDkk4), a secreted, disulphide-rich Wnt inhibitor protein.

Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease

Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.

Structural Stability of Peptidic His-Containing Proton Wire in Solution and in the Adsorbed State

Structural basis for antimicrobial activity of lasiocepsin

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis

Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.

Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR

Structural diversity in p160/CREB-binding protein coactivator complexes

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A

Structure-activity study of macropin, a novel antimicrobial peptide from the venom of solitary bee Macropis fulvipes (Hymenoptera: Melittidae).

The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation.

The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress

The statistical significance of selected sense-antisense peptide interactions.

Three-dimensional structure of a monomeric form of a retroviral protease

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

¹⁵N, ¹³C and ¹H resonance assignments and secondary structure determination of a variable heavy domain of a heavy chain antibody.