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List of works by Geertruy Te Kronnie

A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia.

scientific article

AKR1C enzymes sustain therapy resistance in paediatric T-ALL.

scientific article

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

scientific article published on 27 September 2018

Acute leukemia subclassification: a marker protein expression perspective

scientific article published on June 2004

An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts

scientific article published on 14 January 2016

Antibodies covalently immobilized on actin filaments for fast myosin driven analyte transport

scientific article

Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4 Infant ALL

scientific article published on 10 May 2018

Array-based comparative genomic hybridization analysis reveals chromosomal copy number aberrations associated with clinical outcome in canine diffuse large B-cell lymphoma

scientific article

Blastoderm Structure, Cell Migration and Formation of the Embryonic Shield During Gastrulation in the Carp (Cyprinus carpio); a Scanning Electron Microscopic Study

scientific article published on 01 April 1998

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

scientific article published on 15 July 2016

CRLF2 overexpression identifies an unfavourable subgroup of adult B-cell precursor acute lymphoblastic leukemia lacking recurrent genetic abnormalities

scientific article

Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor

scientific article

CirComPara: A Multi-Method Comparative Bioinformatics Pipeline to Detect and Study circRNAs from RNA-seq Data.

scientific article

Clinical significance of recurrent copy number aberrations in B-lineage acute lymphoblastic leukaemia without recurrent fusion genes across age cohorts

scientific article published on 25 April 2017

Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group

scientific article published on 20 April 2010

Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts

scientific article published on 28 May 2013

Computational analysis of flow-cytometry antigen expression profiles in childhood acute lymphoblastic leukemia: an MLL/AF4 identification.

scientific article published in August 2003

DNA methyltransferase 3a hot-spot locus is not mutated in pediatric patients affected by acute myeloid or T-cell acute lymphoblastic leukemia: an Italian study

scientific article published on 31 August 2011

Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis

scientific article published on 04 October 2016

Development of immunohistochemical characteristics of intrafusal fibres in normal and de-efferented rat muscle spindles

article

Different outcomes of allogeneic hematopoietic stem cell transplant in a pair of twins affected by juvenile myelomonocytic leukemia

scientific article published on 12 December 2013

Differentiation of muscle fiber types in the teleost Brachydanio rerio

scientific article published on 01 June 1978

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

scientific article

Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.

scientific article

Drosophila CAKI/CMG protein, a homolog of human CASK, is essential for regulation of neurotransmitter vesicle release.

scientific article published on 4 May 2005

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

scientific article published on 10 April 2017

Early Relapse in ALL Is Identified by Time to Leukemia in NOD/SCID Mice and Is Characterized by a Gene Signature Involving Survival Pathways

article

Embryonic development in the pig up to the 64-cell stage, with reference to DNA replication and cell cycle times from the third cleavage division

article

Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma

scientific article

Expression Profiling of Circulating Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways

scientific article published on 15 February 2017

Expression of carp-cdx1, a caudal homolog, in embryos of the carp, Cyprinus carpio

scientific article

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

scientific article published on 10 April 2015

Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL

scientific article

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias ⬇️

scientific article

Gain-of-function mutations ininterleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

Gastrulation in Cyprinids: Morphogenesis and Gene Expression

article

Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia

scientific article published on 15 March 2010

Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia.

scientific article published on 7 February 2012

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

scientific article published on 30 September 2014

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

scientific article published on 16 April 2018

Hepatocyte growth factor receptor c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation

scientific article published on 2 August 2007

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia.

scientific article published on 21 March 2017

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 2 March 2018

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

scientific journal article

Immunohistochemical differences in myosin composition among intrafusal muscle fibres

article

Immunophenotype signature as a tool to define prognostic subgroups in childhood acute myeloid leukemia

scientific article published on 01 May 2006

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philade

scientific article published on December 2013

Isolation of carp cDNA clones, representing developmentally-regulated genes, using a subtractive-hybridization strategy.

scientific article

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients

scientific article

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

scientific article published on 28 December 2015

Label-Free Detection of Microvesicles and Proteins by the Bundling of Gliding Microtubules

scientific article published on 5 December 2017

Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.

scientific article published on 2 June 2013

Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome

scientific article

MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study

article

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

scientific article published on 23 June 2009

Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects.

scientific article published on 12 October 2012

Mesoderm differentiation in explants of carp embryos

scientific article published on 01 January 1994

Mesoderm differentiation in explants of carp embryos.

scientific article

Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells

scientific article

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group

scientific article published on 9 March 2016

Myosin isoforms in hindlimb muscles of normal and dystrophic (ReJ129 dy/dy) mice

scientific article published on February 1, 1992

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia.

scientific article published on 14 May 2013

New data on robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures

scientific article

Next-generation sequencing of PTEN mutations for monitoring minimal residual disease in T-cell acute lymphoblastic leukemia

scientific article published on 01 October 2019

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL

scientific article

PAX5/ETV6 alters the gene expression profile of precursor B cells with opposite dominant effect on endogenous PAX5

article

PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy.

scientific article published on 24 September 2009

Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia

scientific article published on 09 April 2012

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

scientific article

Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia

scientific article

Sample solution constraints on motor-driven diagnostic nanodevices

scientific article published on 9 January 2013

Sensing protein antigen and microvesicle analytes using high-capacity biopolymer nano-carriers

scientific article published on 30 November 2015

Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis

Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis.

scientific article published on 15 August 2018

Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in Juvenile myelomonocytic leukemia patients.

scientific article published on 7 January 2018

Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome

scientific article published in May 2017

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model

scientific article

Teleost Yolk Cell Function On Blastoderm Differentiation and Morphogenesis

scientific article published in 2000

The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.

scientific article published on 17 June 2011

The MLL recombinome of acute leukemias in 2013.

scientific article

The carp homeobox gene Ovx1 shows early expression during gastrulation and subsequently in the vagal lobe, the facial lobe and the ventral telencephalon.

scientific article published in March 1998

The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line.

scientific article

The segregation of inner and outer cells in porcine embryos follows a different pattern compared to the segregation in mouse embryos

scientific article published on 01 January 1993

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

scientific article

Two independent gene signatures in pediatric t(4;11) acute lymphoblastic leukemia patients.

scientific article published on 25 June 2009

Ultrafast molecular motor driven nanoseparation and biosensing.

scientific article published on 6 April 2013

Validation of NG2 antigen in identifying BP-ALL patients with MLL rearrangements using qualitative and quantitative flow cytometry: a prospective study

scientific article published on 13 September 2007

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

scientific article published on 12 April 2013

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