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List of works by Rob Field

"Click chemistry"en route to pseudo-starch.

scientific article published on 11 May 2005

2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl azide.

scientific article

96 On the role of manganese cation in the mechanism of α-1,3-fucosyltransferase

scientific article published on 01 November 1997

A Convenient Synthesis of Chiral Nonracemic Vinyl Aziridines

article

A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night

scientific article published on 15 August 2013

A chemical genomic approach identifies matrix metalloproteinases as playing an essential and specific role in Xenopus melanophore migration.

scientific article

A comparison by magnetic circular dichroism of compound X and compound II of horseradish peroxidase

scientific article published on 01 April 1987

A simple method of synthesis of triterpene glycosides similar to glycyrrhizic acid and their hepatoprotective activity in vitro

scientific article published in September 2009

A simple one-pot method for the synthesis of partially protected mono- and disaccharide building blocks using an orthoesterification-benzylation-orthoester rearrangement approach.

scientific article published in September 2003

A survey of chemical methods for sugar-nucleotide synthesis.

scientific article published on 27 July 2009

A synthetic acceptor substrate for Trypanosoma brucei UDP-Gal: GPI anchor side-chain α-galactosyltransferases

scientific article published on 01 August 1998

A versatile gold surface approach for fabrication and interrogation of glycoarrays

scientific article

Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa

scientific article

An Examination of Some Derivatives ofS-Nitroso-1-thiosugars as Vasodilators

scientific article published on 01 June 1997

An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro-maltose derivatives

article

An α-1,6-and α-1,3-linked glucan produced by Leuconostoc citreum ABK-1 alternansucrase with nanoparticle and film-forming properties.

scientific article published on 29 May 2018

Analysis of Two New Arabinosyltransferases Belonging to the Carbohydrate-Active Enzyme (CAZY) Glycosyl Transferase Family1 Provides Insights into Disease Resistance and Sugar Donor Specificity

scientific article published on 14 November 2018

Antibiotics: blocking bacterial defences.

scientific article published in August 2013

Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases.

scientific article

Biomolecular characterization of the levansucrase of Erwinia amylovora, a promising biocatalyst for the synthesis of fructooligosaccharides

scientific article

Carbohydrate CuAAC click chemistry for therapy and diagnosis

scientific article

Cell wall degradation is required for normal starch mobilisation in barley endosperm.

scientific article

Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis.

scientific article published on 21 July 2017

Challenging reaction equilibria

article

Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-d-xylo-4-hexulose 3-epimerase

article

Chemical genetics and cereal starch metabolism: structural basis of the non-covalent and covalent inhibition of barley β-amylase ⬇️

scientific article published on November 18, 2010

Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development.

scientific article

Chemical synthesis of UDP-Glc-2,3-diNAcA, a key intermediate in cell surface polysaccharide biosynthesis in the human respiratory pathogens B. pertussis and P. aeruginosa.

scientific article published on 2 February 2009

Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose-like materials

scientific article published on 29 September 2020

Chemoenzymatic synthesis with distinct Pasteurella heparosan synthases: monodisperse polymers and unnatural structures.

scientific article published on 11 July 2007

Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit Trypanosoma cruzi macrophage invasion. ⬇️

scientific article published on September 2015

Cloning of the full-length isoamylase3 gene from cassava Manihot esculenta Crantz ‘KU50’ and its heterologous expression in E. coli

article

Colorimetric detection of Ricinus communis Agglutinin 120 using optimally presented carbohydrate-stabilised gold nanoparticles.

scientific article published on 19 February 2008

Complex pectin metabolism by gut bacteria reveals novel catalytic functions.

scientific article published on 22 March 2017

Contrasting reactivity of thioglucoside and selenoglucoside donors towards promoters: implications for glycosylation stereocontrol

article

Convergent synthesis of a trisaccharide as its 2-(trimethylsilyl)ethyl glycoside related to the flavonoid triglycoside from Gymnema sylvestre

article

Crystal structure of a novel two domain GH78 family α-rhamnosidase from Klebsiella oxytoca with rhamnose bound.

scientific article published on 3 April 2015

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins

scientific article published on 12 October 2018

CuAAC click chemistry with N-propargyl 1,5-dideoxy-1,5-imino-D-gulitol and N-propargyl 1,6-dideoxy-1,6-imino-D-mannitol provides access to triazole-linked piperidine and azepane pseudo-disaccharide iminosugars displaying glycosidase inhibitory prope

scientific article published on 22 April 2016

Detection of mSiglec-E, in solution and expressed on the surface of Chinese hamster ovary cells, using sialic acid functionalised gold nanoparticles

scientific article published on 18 August 2016

Detection of transglucosidase-catalyzed polysaccharide synthesis on a surface in real time using surface plasmon resonance spectroscopy.

scientific article published on 29 October 2008

Development of a high through-put spectrophotometric assay to monitor Trypanosoma cruzi trans-sialidase ⬇️

scientific article published on 01 August 1997

Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models.

scientific article published on 21 December 2015

Direct oxidation of sugar nucleotides to the corresponding uronic acids: TEMPO and platinum-based procedures

article

Direct synthesis of chiral aziridines from N-tert-butyl-sulfinylketimines

article

Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-l-rhamnose biosynthesis in microalgae.

scientific article published on 22 April 2019

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing.

scientific article published on 8 December 2013

Emerging glycomics technologies

article

Enzymatic liberation of lycotetraose from the Solanum glycoalkaloid alpha-tomatine.

scientific article published in September 2004

Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

scientific article published on 31 December 2014

Enzymatic synthesis using glycoside phosphorylases.

scientific article

Exploring the Glycans of Euglena gracilis.

scientific article published on 15 December 2017

Expression and initial characterization of WbbI, a putative D-Galf:alpha-D-Glc beta-1,6-galactofuranosyltransferase from Escherichia coli K-12.

scientific article published on 21 September 2006

Flexible enzymatic and chemo-enzymatic approaches to a broad range of uridine-diphospho-sugars.

scientific article published on 13 October 2004

Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material

scientific article published on 01 October 2019

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

scientific article published on 30 November 2016

From solution phase to "on-column" chemistry: trichloroacetimidate-based glycosylation promoted by perchloric acid-silica.

scientific article published in October 2005

Gene Discovery for Synthetic Biology: Exploring the Novel Natural Product Biosynthetic Capacity of Eukaryotic Microalgae.

scientific article published on 5 April 2016

Glucose-1-phosphate uridylyltransferase from Erwinia amylovora: Activity, structure and substrate specificity.

scientific article published on 24 August 2017

Glycan Phosphorylases in Multi-Enzyme Synthetic Processes.

scientific article published on 11 August 2017

Glyconanoparticles for colorimetric bioassays

scientific article published on January 2015

Glyconanoparticles for the plasmonic detection and discrimination between human and avian influenza virus.

scientific article published in November 2013

Glycosylation with in situ separation: carbohydrate chemistry on a TLC plate

scientific article published on 23 August 2005

Glycosyltransferases from oat (Avena) implicated in the acylation of avenacins.

scientific article published in July 2013

Heterologous co-expression in E. coli of isoamylase genes from cassava Manihot esculenta Crantz 'KU50' achieves enzyme-active heteromeric complex formation.

scientific article

High-Throughput In Vitro Screening for Inhibitors of Cereal α-Glucosidase

article

Histidines, histamines and imidazoles as glycosidase inhibitors

scientific article published on March 1991

Hydrophobic glycosides of N-acetylglucosamine can act as primers for polylactosamine synthesis and can affect glycolipid synthesis in vivo.

scientific article published on May 1995

Hydrophobic mannosides act as acceptors for trypanosome α-mannosyltransferases

article

Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens

scientific journal article

Identification and evolution of a plant cell wall specific glycoprotein glycosyl transferase, ExAD.

scientific article published on 30 March 2017

Identification of Euglena gracilis β-1,3-glucan phosphorylase and establishment of a new glycoside hydrolase (GH) family GH149.

scientific article published on 9 January 2018

Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism

scientific article

Indirect approach to C-3 branched 1,2-cis-glycofuranosides: synthesis of aceric acid glycoside analogues.

scientific article published on 7 November 2007

Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses

scientific article published on 14 March 2018

Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides.

scientific article published on 7 April 2008

Isolation and Characterization of a Double Stranded DNA Megavirus Infecting the Toxin-Producing Haptophyte Prymnesium parvum.

scientific article published on 09 March 2017

Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

scientific article published on 26 April 2016

Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives.

scientific article published on 19 August 2017

New Investigators in Glycoscience 2

scholarly article by Rob Field published June 2017 in Carbohydrate Research

New conformational constraints in isotopically (13C) enriched oligosaccharides

scientific article published on 01 February 1998

New investigators in glycoscience

scientific article

New thiopyrazolo[3,4-d]pyrimidine derivatives as anti-mycobacterial agents

article

Overexpression, purification, crystallization and data collection on the Bordetella pertussis wlbD gene product, a putative UDP-GlcNAc 2'-epimerase.

scientific article

Peracetylated alpha-D-glucopyranosyl fluoride and peracetylated alpha-maltosyl fluoride.

scientific article published on 3 February 2010

Practical de-O-acylation reactions promoted by molecular sieves

article

Predicting Protein Function from Structure—The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis

scientific article

Preparative and Kinetic Analysis of β-1,4- and β-1,3-Glucan Phosphorylases Informs Access to Human Milk Oligosaccharide Fragments and Analogues Thereof

scientific article published on 30 December 2019

Probing Carbohydrate-Protein Interactions by High-Resolution NMR Spectroscopy ⬇️

scientific article published on January 1, 1998

Probing the Breadth of Macrolide Glycosyltransferases: In Vitro Remodeling of a Polyketide Antibiotic Creates Active Bacterial Uptake and Enhances Potency

article

Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries

scientific article

Profiling of Sugar Nucleotides.

scientific article published on 23 July 2017

Protein–Carbohydrate Interactions in Infectious Diseases. Edited by Carole A. Bewley

scholarly article by Rob Field published 16 April 2007 in ChemMedChem

Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis ⬇️

scientific article published on January 1996

Recent applications of the Cu(I)-catalysed Huisgen azide-alkyne 1,3-dipolar cycloaddition reaction in carbohydrate chemistry.

scientific article published on 5 March 2007

Revisiting the Language of Glycoscience: Readers, Writers and Erasers in Carbohydrate Biochemistry

scientific article published on 04 November 2019

RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation

scientific journal article

Silver and Gold Glyconanoparticles for Colorimetric Bioassays

article

Small molecule inhibitors to dissect starch degradation during cereal germination

Solution structure of the complex between the B-subunit homopentamer of verotoxin VT-1 from Escherichia coli and the trisaccharide moiety of globotriaosylceramide.

scientific article

Standards for plant synthetic biology: a common syntax for exchange of DNA parts.

scientific article

Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1).

scientific article

Structural and functional analyses of glycoside hydrolase 138 enzymes targeting chain A galacturonic acid in the complex pectin rhamnogalacturonan II

scientific article published on 15 March 2019

Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase.

scientific article published on 29 March 2018

Structural basis of trimannoside recognition by concanavalin A

scientific article

Structural characterisation of the capsular polysaccharide expressed by Burkholderia thailandensis strain E555:: wbiI (pKnock-KmR) and assessment of the significance of the 2-O-acetyl group in immune protection

scientific article published on 21 September 2017

Structure of Streptomyces Maltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis Target

scientific article

Structure of a glycoconjugate in solution and in complex with an antibody Fv fragment

article

Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: fluorinated substrates, kinetics and equilibria.

scientific article published on 23 January 2009

Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays

article

Synthesis and 1H NMR characterization of the six isomeric mono-O-sulfates of 8-methoxycarbonyloct-1-yl O-β-d-galactopyranosyl-(1 → 4)-2-acetamido-2-deoxy-β-d-glucopyranoside

article

Synthesis and evaluation of mimetics of UDP and UDP-alpha-D-galactose, dTDP and dTDP-alpha-D-glucose with monosaccharides replacing the key pyrophosphate unit.

scientific article

Synthesis of L-arabinose-containing fragments of the oat root saponin Avenacin A-1.

scientific article published in May 2004

Synthesis of a 2,3,4-triglycosylated rhamnoside fragment of rhamnogalacturonan-II side chain A using a late stage oxidation approach.

scientific article

Synthesis of apiose-containing oligosaccharide fragments of the plant cell wall: fragments of rhamnogalacturonan-II side chains A and B, and apiogalacturonan ⬇️

scientific article published on August 17, 2011

Synthesis of fluorescently labelled rhamnosides: probes for the evaluation of rhamnogalacturonan II biosynthetic enzymes.

scientific article published on 6 April 2011

Synthesis of glyceryl glycosides related to A-type prymnesin toxins.

scientific article published on 17 April 2018

Synthesis of the branched-chain sugar aceric acid: a unique component of the pectic polysaccharide rhamnogalacturonan-II.

scientific article

Synthesis of triazole-linked pseudo-starch fragments

article

Targeted photodynamic therapy of breast cancer cells using lactose-phthalocyanine functionalized gold nanoparticles

scientific article

Temperature-dependent inulin nanoparticles synthesized by Lactobacillus reuteri 121 inulosucrase and complex formation with flavonoids

scientific article published on 02 July 2019

The 1.6-Å resolution crystal structure of NovW: A 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides

article

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

scientific article

The Maltase Involved in Starch Metabolism in Barley Endosperm Is Encoded by a Single Gene

scientific article

The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU.

scientific article published on 23 April 2018

The hydrophobic mannoside Man alpha 1-6Man alpha 1-S-(CH2)7-CH3 acts as an acceptor for the UDP-Gal:glycosylphosphatidylinositol anchor alpha 1,3-galactosyltransferase of Trypanosoma brucei.

scientific article published on August 1995

The impact of aminopyrene trisulfonate (APTS) label in acceptor glycan substrates for profiling plant pectin β-galactosyltransferase activities.

scientific article published on 18 July 2016

The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme.

scientific article

The protosteryl and dammarenyl cation dichotomy in polycyclic triterpene biosynthesis revisited: has this 'rule' finally been broken?

scientific article published on 01 August 2019

The saponins – polar isoprenoids with important and diverse biological activities ⬇️

scientific article published on May 16, 2011

The structure of a GH149 β-(1 → 3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-β-(1 → 3)-glucose (laminaribiose) phosphorylase

scientific article published on 06 June 2019

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry.

scientific article published on 20 August 2015

Thioctic acid amides: convenient tethers for achieving low nonspecific protein binding to carbohydrates presented on gold surfaces.

scientific article published on 27 May 2005

Underpinning Starch Biology with in vitro Studies on Carbohydrate-Active Enzymes and Biosynthetic Glycomaterials

scientific article

Unraveling the subtleties of β-(1→3)-glucan phosphorylase specificity in the GH94, GH149, and GH161 glycoside hydrolase families

scientific article published on 28 February 2019

Unravelling the Specificity of Laminaribiose Phosphorylase from Paenibacillus sp. YM-1 towards Donor Substrates Glucose/Mannose 1-Phosphate by Using X-ray Crystallography and Saturation Transfer Difference NMR Spectroscopy

scientific article published on 04 July 2018

Versatile high resolution oligosaccharide microarrays for plant glycobiology and cell wall research

scientific article

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