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List of works by Michael O'Dwyer

5-Azacytidine for the treatment of myelodysplastic syndromes.

scientific article published on 27 April 2013

A cell culture system that mimics chronic lymphocytic leukemia cells microenvironment for drug screening and characterization.

scientific article published on January 2013

A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response

scientific article (publication date: 2014)

A multi‐centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia ⬇️

scientific article published on August 2, 2013

A novel molecular assay using hybridisation probes and melt curve analysis for CALR exon 9 mutation detection in myeloproliferative neoplasms.

scientific article published on 31 January 2017

AKT as a therapeutic target in multiple myeloma

scientific article

Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia.

scientific article published on 13 March 2003

An European Myeloma Network recommendation on tools for diagnosis and monitoring of multiple myeloma: what to use and when

scholarly article by Jo Caers et al published 31 August 2018 in Haematologica

Atypical cause of prolonged myelosuppression ⬇️

scientific article published on December 9, 2009

COVID-19 infection induces readily detectable morphologic and inflammation-related phenotypic changes in peripheral blood monocytes

scientific article published on 11 October 2020

Cdc7 kinase - a new target for drug development.

scientific article published on January 2010

Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models

scientific article published on 24 July 2013

Chromosomal abnormalities in Ph- cells of patients on imatinib

scientific article published in October 2003

Chronic myelogenous leukaemia--new therapeutic principles.

scientific article

Chronic myelogenous leukemia

scientific article published on 01 January 2003

Clofarabine in the treatment of poor risk acute myeloid leukaemia.

scientific article published in September 2010

Clonal evolution and lack of cytogenetic response are adverse prognostic factors for hematologic relapse of chronic phase CML patients treated with imatinib mesylate

scientific article published on 25 September 2003

Current and emerging immunotherapeutic approaches to the treatment of multiple myeloma.

scientific article published on 18 June 2019

Current use of imatinib in the treatment of chronic myeloid leukemia.

scientific article published in March 2003

CyBorD-DARA is potent initial induction for MM and enhances ADCP: initial results of the 16-BCNI-001/CTRIAL-IE 16-02 study

scientific article published on 01 June 2019

Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate.

scientific article published in March 2003

Drugging the unfolded protein response in acute leukemias

scientific article (publication date: 2015)

E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271.

scientific article published on 25 April 2017

Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma.

scientific article published on 31 May 2013

Flushing out the diagnosis

scientific article published on 02 July 2013

Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics

scientific article

Hematopathologic and cytogenetic findings in imatinib mesylate-treated chronic myelogenous leukemia patients: 14 months' experience

scientific article published in July 2002

Home administration of bortezomib: making a difference to myeloma patients' lives

scientific article published on 8 October 2009

How to monitor patients with chronic myelogenous leukemia.

scientific article published on October 2003

Hypoxia Impairs NK Cell Cytotoxicity through SHP-1-Mediated Attenuation of STAT3 and ERK Signaling Pathways

scientific article published on 19 June 2020

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia ⬇️

scientific article

In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia

scientific article published on July 2002

Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.

scientific article

Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective.

scientific article

Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members.

scientific article

Long-term safety of single-agent ibrutinib in patients with chronic lymphocytic leukemia in 3 pivotal studies

scientific article published on 01 June 2019

Mechanisms of action of a dual Cdc7/Cdk9 kinase inhibitor against quiescent and proliferating CLL cells.

scientific article published on 18 July 2011

Mesenteric venous thrombosis secondary to an unsuspected JAK2 V617F-positive myeloproliferative disorder.

scientific article

Molecular response to first line nilotinib in a patient with e19a2 BCR-ABL1 chronic myeloid leukemia

scientific article published on 01 September 2011

Multifaceted approach to the treatment of bcr-abl-positive leukemias.

scientific article

Neurotrophins and B-cell malignancies

scientific article published on 23 September 2015

New developments in the treatment of multiple myeloma - clinical utility of daratumumab.

scientific article published on 11 April 2017

Nilotinib 300 mg BID as frontline treatment of CML: prospective analysis of the Xpert BCR-ABL monitor system and significance of 3-month molecular response

scientific article published in December 2013

Outcome in elderly acute myeloid leukaemia.

scientific article

Perifosine--a new option in treatment of acute myeloid leukemia?

scientific article published on 09 August 2013

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

scientific article published on 27 March 2017

Pulmonary hemorrhage in a hemophiliac simulating a lung neoplasm.

scientific article published in August 2000

RNA interference for multiple myeloma therapy: targeting signal transduction pathways

scientific article published on 20 July 2015

Recent advancements in the treatment of chronic myelogenous leukemia

scientific article

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

scientific article published in Scientific Reports

Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in no

scientific article published on 19 September 2017

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

scientific article published on 01 March 2001

STI571 as a targeted therapy for CML.

scientific article

STI571: a paradigm of new agents for cancer therapeutics

scientific article

Successful treatment of aggressive post transplant lymphoproliferative disorder using rituximab.

scientific article published in October 2000

TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.

scientific article

Targeting AML through DR4 with a novel variant of rhTRAIL

scientific article

Targeting Selectins and Their Ligands in Cancer

scientific article

Targeting the Pim kinases in multiple myeloma

scientific article (publication date: 2015)

The CD38low natural killer cell line KHYG1 transiently expressing CD16F158V in combination with daratumumab targets multiple myeloma cells with minimal effector NK cell fratricide

scientific article published on 09 January 2020

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis.

scientific article published on 15 March 2011

The cancer glycome: carbohydrates as mediators of metastasis

scientific article

The dual inhibitor of the phosphoinositol-3 and PIM kinases, IBL-202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment

scientific article published on 05 July 2018

The impact of clonal evolution on response to imatinib mesylate (STI571) in accelerated phase CML.

scientific article published in September 2002

The role of inflammation in leukaemia

scientific article published on January 2014

The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma

scientific article

The use of single armed observational data to closing the gap in otherwise disconnected evidence networks: a network meta-analysis in multiple myeloma. ⬇️

scientific article published on 28 June 2018

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