List of works - Joseph J Mattapallil

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum.

scientific article published on 10 April 2018

Accelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixafor

scientific article (publication date: July 2011)

Acute HIV infection: it takes more than guts

scientific article published on January 2006

Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

scientific article published on July 2009

An early expansion of CD8alphabeta T cells, but depletion of resident CD8alphaalpha T cells, occurs in the intestinal epithelium during primary simian immunodeficiency virus infection.

scientific article published on April 2000

Anti-retroviral therapy fails to restore the severe Th-17: Tc-17 imbalance observed in peripheral blood during simian immunodeficiency virus infection.

scientific article published on October 2009

Antiretroviral therapy prior to acute viral replication preserves CD4 T cells in the periphery but not in rectal mucosa during acute simian immunodeficiency virus infection

scientific article published on 03 September 2008

CD4 T cell subsets in the mucosa are CD28+Ki-67-HLA-DR-CD69+ but show differential infection based on alpha4beta7 receptor expression during acute SIV infection.

scientific article

CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

scientific article published on 28 September 2009

Captopril mitigates splenomegaly and myelofibrosis in the Gata1 murine model of myelofibrosis

article

Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans

scientific article

Chronic simian immunodeficiency virus infection is associated with contrasting phenotypes of dysfunctional Bcl6 germinal center B cells or Bcl6 Bcl2 non-germinal center B cells

scholarly article by Olusegun O Onabajo et al published November 2018 in Journal of Cellular and Molecular Medicine

Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection

scientific article

Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis

scientific article published on 15 February 2008

Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques

scientific article

Early treatment with reverse transcriptase inhibitors significantly suppresses peak plasma IFNα in vivo during acute simian immunodeficiency virus infection

scientific article published on 9 September 2016

Estimating the impact of vaccination on acute simian-human immunodeficiency virus/simian immunodeficiency virus infections

scientific article published on 17 September 2008

Estimating the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut.

scientific article

Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses

scientific article

Gastrointestinal tract and the mucosal macrophage reservoir in HIV infection

scientific article

Gender differences in innate responses and gene expression profiles in memory CD4 T cells are apparent very early during acute simian immunodeficiency virus infection

scientific article published on 06 September 2019

Genetic immunization in the lung induces potent local and systemic immune responses

scientific article

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

scientific article

HIV vaccines: can mucosal CD4 T cells be protected?

scientific article published on July 2006

High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections

scholarly article

Human Serum With High Neutralizing Antibody Titers Against Both Zika and Dengue Virus Shows Delayed In Vitro Antibody-Dependent Enhancement of Dengue Virus Infection

scientific article published in July 2018

Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune response

scientific article

Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization

scientific article

Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection

scientific article published on February 2009

Infectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivo

scientific article

Interferon-α Subtypes As an Adjunct Therapeutic Approach for Human Immunodeficiency Virus Functional Cure.

scientific article published on 22 February 2018

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

scientific article

Loss and dysregulation of Th17 cells during HIV infection

scientific article

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

scientific article (publication date: 28 April 2005)

Mucosa and vaccine-induced immune protection in nonhuman primates

scientific article published on May 2008

Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection

scientific article published on 16 November 2011

Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques

scientific article published on 5 September 2017

Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency

scientific article published on 30 July 2008

Resting naive CD4+ T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques

scientific article

Rhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype

scientific article

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

scientific article published on 17 April 2007

Significant Depletion of CD4(+) T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4(+) T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy

scientific article published on 30 April 2015

Significant mobilization of both conventional and regulatory T cells with AMD3100.

scientific article published on 11 October 2011

Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines

scientific article published on 27 May 2019

Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection

scientific article published on 17 April 2013

Suppression of transforming growth factor β receptor 2 and Smad5 is associated with high levels of microRNA miR-155 in the oral mucosa during chronic simian immunodeficiency virus infection

scientific article

Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge

scientific article published in August 2006

T-cell dynamics during acute SIV infection

scientific article

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

scientific article

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

scientific article

Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge

scientific article

Zika convalescent macaques display delayed induction of anmanestic cross-neutralizing antibody responses after dengue infection.

scientific article published on 13 July 2018

List of works by Joseph J Mattapallil

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum.

Accelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixafor

Acute HIV infection: it takes more than guts

Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

An early expansion of CD8alphabeta T cells, but depletion of resident CD8alphaalpha T cells, occurs in the intestinal epithelium during primary simian immunodeficiency virus infection.

Anti-retroviral therapy fails to restore the severe Th-17: Tc-17 imbalance observed in peripheral blood during simian immunodeficiency virus infection.

Antiretroviral therapy prior to acute viral replication preserves CD4 T cells in the periphery but not in rectal mucosa during acute simian immunodeficiency virus infection

CD4 T cell subsets in the mucosa are CD28+Ki-67-HLA-DR-CD69+ but show differential infection based on alpha4beta7 receptor expression during acute SIV infection.

CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

Captopril mitigates splenomegaly and myelofibrosis in the Gata1 murine model of myelofibrosis

Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans

Chronic simian immunodeficiency virus infection is associated with contrasting phenotypes of dysfunctional Bcl6 germinal center B cells or Bcl6 Bcl2 non-germinal center B cells

Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection

Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis

Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques

Early treatment with reverse transcriptase inhibitors significantly suppresses peak plasma IFNα in vivo during acute simian immunodeficiency virus infection

Estimating the impact of vaccination on acute simian-human immunodeficiency virus/simian immunodeficiency virus infections

Estimating the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut.

Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses

Gastrointestinal tract and the mucosal macrophage reservoir in HIV infection

Gender differences in innate responses and gene expression profiles in memory CD4 T cells are apparent very early during acute simian immunodeficiency virus infection

Genetic immunization in the lung induces potent local and systemic immune responses

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

HIV vaccines: can mucosal CD4 T cells be protected?

High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections

Human Serum With High Neutralizing Antibody Titers Against Both Zika and Dengue Virus Shows Delayed In Vitro Antibody-Dependent Enhancement of Dengue Virus Infection

Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune response

Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization

Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection

Infectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivo

Interferon-α Subtypes As an Adjunct Therapeutic Approach for Human Immunodeficiency Virus Functional Cure.

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

Loss and dysregulation of Th17 cells during HIV infection

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Mucosa and vaccine-induced immune protection in nonhuman primates

Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection

Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques

Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency

Resting naive CD4+ T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques

Rhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

Significant Depletion of CD4(+) T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4(+) T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy

Significant mobilization of both conventional and regulatory T cells with AMD3100.

Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines

Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection

Suppression of transforming growth factor β receptor 2 and Smad5 is associated with high levels of microRNA miR-155 in the oral mucosa during chronic simian immunodeficiency virus infection

Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge

T-cell dynamics during acute SIV infection

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge

Zika convalescent macaques display delayed induction of anmanestic cross-neutralizing antibody responses after dengue infection.