List of works by Paolo Arosio

A human mitochondrial ferritin encoded by an intronless gene

scientific journal article

A mutational analysis of the epitopes of recombinant human H-ferritin

scientific article published on 01 June 1990

A new mutation (G51C) in the iron-responsive element (IRE) of l-ferritin associated with hyperferritinaemia-cataract syndrome decreases the binding affinity of the mutated IRE for iron-regulatory proteins

scientific article published on 01 March 2000

A novel deletion of the l-ferritin iron-responsive element responsible for severe hereditary hyperferritinaemia-cataract syndrome

scientific article published on 01 March 2002

Analysis of ferritin genes in Parkinson disease

article

Analysis of ferritins in lymphoblastoid cell lines and in the lens of subjects with hereditary hyperferritinemia-cataract syndrome.

scientific article published on June 1998

Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders.

scientific article published on 17 October 2010

Analysis of the iron status of professional cyclists during a 3-week road race

scientific article published on 01 March 1988

Antiferritin single-chain Fv fragment is a functional protein with properties of a partially structured state: comparison with the completely folded V(L) domain.

scientific article published on July 2000

Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma

scientific article published on 01 July 2003

Basic and acidic isoferritins in the serum of patients with Hodgkin's disease

scientific article published on 01 March 1983

Behavioral characterization of mouse models of neuroferritinopathy

scientific article

Binding and suppressive activity of human recombinant ferritins on erythroid cells

scientific article published on 01 April 1992

Biochemical and genetic defects underlying human congenital hypotransferrinemia

scientific article published on 01 January 2000

Biochemical and immunological characterization of recombinant allergen Lol p 1

scientific article published on 01 November 1997

Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli

scientific article

Biofortification for combating 'hidden hunger' for iron.

scientific article

Biologic and clinical significance of red cell ferritin

scientific article published on 01 November 1983

Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration

scientific article published on 15 August 2014

Blotting analysis of native IRP1: a novel approach to distinguish the different forms of IRP1 in cells and tissues

scientific article published on 01 January 2004

Carbon dioxide and the membrane artificial lung: their roles in the prevention and treatment of respiratory failure

scientific article published on 01 January 1982

Characteristics and expression of binding sites specific for ferritin H-chain on human cell lines

scientific article published on 01 March 1988

Characteristics of ferritins in human milk secretions: Similarities to serum and tissue isoferritins

scientific article published on 01 December 1986

Characterization and distribution of ferritin binding sites in the adult mouse brain.

scientific article

Characterization of the H- and L-subunit ratios of ferritins by sodium dodecyl sulfate-capillary gel electrophoresis.

scientific article

Characterization of the ferritin receptors of human T lymphoid (MOLT-4) cells

scientific article published on March 1, 1992

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

scientific article published on 05 July 2006

Chemically and biologically harmless versus harmful ferritin/copper-metallothionein couples.

scientific article published on 4 November 2014

Chemico-physical and functional differences between H and L chains of human ferritin.

scientific article

Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology

scientific article published on 01 August 2006

Construction of a ferroxidase center in human ferritin L-chain

scientific article published on 01 December 1994

Crystallization and preliminary X-ray diffraction data of mouse L-chain apoferritin crystals.

scientific article

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

scientific article published on 30 January 2007

Deficient ferritin immunoreactivity in tissues from niemann-pick type C patients: extension of findings to fetal tissues, H and L ferritin isoforms, but also one case of the rare Niemann-Pick C2 complementation group

scientific article published on 01 July 2000

Denaturing HPLC analysis of DNA deletions and insertions

scientific article published on 01 July 2003

Development of a monoclonal antibody against human heart ferritin and its application in an immunoradiometric assay

scientific article published on 01 November 1983

Double-gradient denaturing gradient gel electrophoresis assay for identification of L-ferritin iron-responsive element mutations responsible for hereditary hyperferritinemia-cataract syndrome: identification of the new mutation C14G

scientific article published on 01 March 2001

Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.

scientific article published in January 2009

ELISA reveals a difference in the structure of substantia nigra ferritin in Parkinson's disease and incidental Lewy body compared to control.

scientific article published in February 2007

Effect of Phosphate and Ferritin Subunit Composition on the Kinetics, Structure, and Reactivity of the Iron Core in Human Homo- and Heteropolymer Ferritins

scientific article published in 2022

Effect of acidic and basic isoferritins on in vitro growth of human granulocyte-monocyte progenitors.

scientific article published in March 1986

Effect of cell proliferation on H-ferritin receptor expression in human T lymphoid (MOLT-4) cells.

scientific article published on August 1992

Effects of modifications near the 2-, 3- and 4-fold symmetry axes on human ferritin renaturation.

scientific article published on March 1997

Electrophoretic analysis of horse tissue ferritins at different pH values

scientific article published on 01 October 1980

Energetics of surface confined ferritin during iron loading

scientific article published on 17 May 2016

Erythrocyte ferritin in thalassemia syndromes

scientific article published on 01 January 1984

Evaluation of heart isoferritins in serum using specific monoclonal antibodies

scientific article published on 01 July 1984

Evaluation of iron stores in patients with alcoholic liver disease: role of red cell ferritin

scientific article published on 01 January 1988

Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin ⬇️

scientific article published on December 1, 1992

Evidence that a salt bridge in the light chain contributes to the physical stability difference between heavy and light human ferritins.

scientific article published on July 1992

Expression and characterization of the ferritin binding domain of Nuclear Receptor Coactivator-4 (NCOA4).

scientific article published on 25 July 2017

Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation.

scientific article published on 25 February 2015

Expression, refolding, and ferritin-binding activity of the isolated VL-domain of monoclonal antibody F11

scientific article published on 01 September 2000

Facilitated diffusion of iron(II) and dioxygen substrates into human H-chain ferritin. A fluorescence and absorbance study employing the ferroxidase center substitution Y34W.

scientific article published on December 2008

Ferritin exhibits Michaelis-Menten behavior with oxygen but not with iron during iron oxidation and core mineralization

scientific article published on 01 April 2019

Ferritin ferroxidase activity: a potent inhibitor of osteogenesis.

scientific article published on January 2010

Ferritin in human milk

scientific article published on 01 March 1984

Ferritin in the red cells of normal subjects and patients with iron deficiency and iron overload

scientific article published on 01 April 1983

Ferritin prevents calcification and osteoblastic differentiation of vascular smooth muscle cells.

scientific article published on 7 May 2009

Ferritin, cellular iron storage and regulation

scientific article published on 27 March 2017

Ferritins in malignant and non-malignant lymphoid cells

scientific article published on 01 January 1986

Ferritins: a family of molecules for iron storage, antioxidation and more.

scientific article published on 26 September 2008

Ferroportin gene silencing induces iron retention and enhances ferritin synthesis in human macrophages

article

Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study.

scientific article published in September 2002

Ferroxidase kinetics of human liver apoferritin, recombinant H-chain apoferritin, and site-directed mutants

scientific article published on 01 September 1993

Functional and Immunological Analysis of Recombinant Mouse H- and L-Ferritins from Escherichia coli

scientific article published on 01 June 2000

Fusion of the antiferritin antibody VL domain to barnase results in enhanced solubility and altered pH stability.

scientific article published in January 2004

Gel filtration analysis of equine ferritin subunits

scientific article published on 01 August 1979

Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3).

scientific article published in November 2002

Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo.

scientific article published on 07 January 2014

H and L ferritins in myocardium in iron overload

scientific article published in November 1991

Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells

scientific article published on 01 May 2002

Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation

scientific article

Hepcidin antagonists for potential treatments of disorders with hepcidin excess

scientific article

Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA ⬇️

article by M Cazzola et al published 15 July 1997 in Blood

Human ferritin H-chains can be obtained in non-assembled stable forms which have ferroxidase activity

scientific article published on 01 December 1993

Human isoferritins in normal and disease states

scientific article published on January 1, 1977

Human recombinant antibody fragments specific for a rye-grass pollen allergen: characterization and potential applications.

scientific article

Human serum ferritin G-peptide is recognized by anti-L ferritin subunit antibodies and concanavalin-A

scientific article published on 01 February 1987

Identification of H- and L-ferritin subunit binding sites on human T and B lymphoid cells

scientific article published on 01 October 1989

Identification of New Mutations of the HFE, Hepcidin, and Transferrin Receptor 2 Genes by Denaturing HPLC Analysis of Individuals with Biochemical Indications of Iron Overload

article

Identification of new mutations of hepcidin and hemojuvelin in patients with HFE C282Y allele

scientific article published on 01 November 2004

Identification of the EPR-active iron-nitrosyl complexes in mammalian ferritins

scientific article published on 01 March 1994

Identification of the ferroxidase centre in ferritin

scientific article published on 01 August 1989

Identification of two novel mutations in the 5'-untranslated region of H-ferritin using denaturing high performance liquid chromatography scanning.

scientific article

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

scientific article

Immunocytochemical detection of ferritin in human bone marrow and peripheral blood cells using monoclonal antibodies specific for the H and L subunit

scientific article published on 01 November 1990

Immunohistochemical evidence for a lack of ferritin in duodenal absorptive epithelial cells in idiopathic hemochromatosis.

scientific article published in April 1989

Immunohistochemistry of HFE in the duodenum of C282Y homozygotes with antisera for recombinant HFE protein

scientific article published on 01 April 2000

Immunologic differences in human isoferritins: implications for immunologic quantitation of serum ferritin.

scientific article published in January 1977

Influence of site-directed modifications on the formation of iron cores in ferritin

scientific article published on 01 October 1991

Interactions of succinate dehydrogenase with cyanide

scientific article published on 01 September 1973

International collaborative study to evaluate a recombinant L ferritin preparation as an International Standard.

scientific article

Iron Homeostasis in Health and Disease

scientific article

Iron Mobilization from Ferritin in Yeast Cell Lysate and Physiological Implications

scientific article published on 29 May 2022

Iron acquisition in Bacillus cereus: the roles of IlsA and bacillibactin in exogenous ferritin iron mobilization

scientific article

Iron as Therapeutic Target in Human Diseases

scientific article published on 05 December 2019

Iron detoxifying activity of ferritin

scientific article published on 01 December 1990

Iron oxidation in sheep, horse and recombinant human apoferritins

scientific article published on 01 January 1994

Iron release from ferritin by flavin nucleotides.

scientific article published on 29 May 2013

Iron(II) and hydrogen peroxide detoxification by human H-chain ferritin. An EPR spin-trapping study

scientific article published on 01 March 2006

Is hydrogen peroxide produced during iron(II) oxidation in mammalian apoferritins?

scientific article published on 01 September 2001

Kinetic studies of iron deposition catalyzed by recombinant human liver heavy and light ferritins and Azotobacter vinelandii bacterioferritin using O2 and H2O2 as oxidants

scientific article published on 07 January 2005

Lol pII allergen. Production and characterization of the recombinant protein and human antibody fragments

scientific article published on 01 January 1996

Macrophage and epithelial cell H-ferritin expression regulates renal inflammation

scientific article published on 15 April 2015

Measurement of ferritin-bearing lymphocytes in man. Preliminary studies on the use of monoclonal antibodies specific for the L and H subunits of ferritin

scientific article published on 01 February 1987

Mechanisms of regulation of ferritin synthesis in rat liver during experimental inflammation

scientific article published on 01 April 1988

Methodological effects on the quantitation of serum ferritin by radio- and enzymoimmunoassays

scientific article published on 01 April 1982

Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

scientific article

Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism.

scientific article published in February 2006

Mitochondrial ferritin deficiency reduces male fertility in mice

scientific article published on 9 January 2017

Mitochondrial ferritin.

scientific article published on October 2004

Mitochondrial ferritin: a new player in iron metabolism

scientific article

Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.

scientific article

Multiple Pathways for Mineral Core Formation in Mammalian Apoferritin. The Role of Hydrogen Peroxide†

scientific article published on 01 March 2003

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

scientific article published in 1985

Multiple subunits in human ferritins: evidence for hybrid molecules

scientific article published on 01 April 1975

Mutant L-chain ferritins that cause neuroferritinopathy alter ferritin functionality and iron permeability

scientific article published on 01 October 2019

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

scientific article

Mutations of ferritin H chain C-terminus produced by nucleotide insertions have altered stability and functional properties

scientific article published on 01 May 2006

New TFR2 mutations in young Italian patients with hemochromatosis

scientific article published on 01 February 2008

New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity

scientific article published on February 2008

New signaling pathways for hepcidin regulation.

scientific article published in March 2014

No Evidence of Relation Between Peripheral Neuropathy and Presence of Hemochromatosis Gene Mutations in HIV-1-Positive Patients

article

Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia.

scientific article published on 8 April 2017

Novel functional changes during podocyte differentiation: increase of oxidative resistance and H-ferritin expression

scientific article

On ferritin heterogeneity. Further evidence for heteropolymers

scientific article

Origin of the unusual kinetics of iron deposition in human H-chain ferritin

scientific article published on 01 March 2005

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

scientific article published on 01 October 1999

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

scientific article

Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo

scientific article published on 21 September 2014

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

scientific article published on 23 September 2009

Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells

scientific article published on 26 October 2015

Production and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains

scientific article published on 15 December 2016

Production and characterization of recombinant heteropolymers of human ferritin H and L chains

scientific article published on 01 June 1993

Production of a soluble and functional recombinant streptavidin in Escherichia coli

scientific article published on 01 November 1998

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury.

scientific article published on 9 September 2013

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

scientific article published on 27 December 2006

Reaction paths of iron oxidation and hydrolysis in horse spleen and recombinant human ferritins.

scientific article published in July 1998

Recombinant human hepcidin expressed in Escherichia coli isolates as an iron containing protein

scientific article published on 01 September 2005

Reconstitution of manganese oxide cores in horse spleen and recombinant ferritins.

scientific article published in April 1995

Redox reactivity of animal apoferritins and apoheteropolymers assembled from recombinant heavy and light human chain ferritins

scientific article published on 01 March 1999

Regional and cellular distribution of mitochondrial ferritin in the mouse brain

scientific article published on 01 November 2010

Regulation of ferritin synthesis in malignant and non-malignant lymphoid cells

scientific article published on 01 September 1986

Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.

scientific article

Scanning mutations of the 5'UTR regulatory sequence of l-ferritin by denaturing high-performance liquid chromatography: identification of new mutations

scientific article published on 01 April 2003

Selective crystallization of horse isoferritins

scientific article published on 01 April 1983

Serum ferritin evaluation with radioimmunoassays specific for HeLa and liver ferritin types

scientific article published on 01 November 1981

Serum ferritin in type I diabetes

Solubilization from spinach thylakoids of a higher molecular weight form of ferredoxin-NADP+ reductase.

scientific article published in March 1980

Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts

scientific article

Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control

scientific article published on 01 August 1991

Structural and immunologic relationships of human isoferritins in normal and disease states

scientific article published on January 1, 1976

Structural description of the active sites of mouse L-chain ferritin at 1.2 A resolution

scientific article

Structural heterogeneity and subunit composition of horse ferritins.

scientific article

Structure and immunochemistry of isoferritins

scientific article published on 01 July 1984

Structure of mouse L-chain ferritin at 1.6 A resolution

scientific article

Structure, function, and evolution of ferritins.

scientific article

Study of ferritin self-assembly and heteropolymer formation by the use of Fluorescence Resonance Energy Transfer (FRET) technology

scientific article published on 16 December 2016

Successful treatment of experimental neonatal respiratory failure using extracorporeal membrane lung assist

scientific article published on 01 November 1986

Sucrosomial Iron Supplementation in Mice: Effects on Blood Parameters, Hepcidin, and Inflammation

The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells

scientific article published on 02 September 2019

The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization

scientific article published on 5 March 2015

The Role of the L-Chain in Ferritin Iron Incorporation

scientific article published on 01 May 1994

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

scientific article

The ferritins: molecular properties, iron storage function and cellular regulation

scientific journal article

The importance of iron in pathophysiologic conditions

scientific article published on 24 February 2015

The influence of purified recombinant human heavy-subunit and light-subunit ferritins on colony formation in vitro by granulocyte-macrophage and erythroid progenitor cells

scientific article published on 01 December 1986

The putative "nucleation site" in human H-chain ferritin is not required for mineralization of the iron core.

scientific article

The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

scholarly article

The sedimentation properties of ferritins. New insights and analysis of methods of nanoparticle preparation.

scientific article

The use of the extracorporeal membrane lung in the successful resuscitation of severely hypoxic and hypercapnic fetal lambs

scientific article published on 01 January 1982

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.

scientific article published on 15 July 2010

Transient overexpression of human H- and L-ferritin chains in COS cells.

scientific article published on February 1998

Tyrosyl radical formation during the oxidative deposition of iron in human apoferritin

scientific article published on 01 June 1995

Use of a reference standard to improve the accuracy and precision of seven kits for determination of ferritin in serum.

scientific article published in February 1984

Vanadyl(IV) binding to mammalian ferritins. An EPR study aided by site-directed mutagenesis.

scientific article published in May 2000

[Determination of human serum ferritin by latex immunoassay]

scientific article published on 01 January 1984

mu-1,2-Peroxobridged di-iron(III) dimer formation in human H-chain ferritin.

scientific article published in May 2002

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