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List of works by Anna deFazio

A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers.

scientific article published on 06 December 2016

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

scientific article published on 25 June 2019

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer

scientific article

ABCB1 (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/carboplatin chemotherapy.

scientific article published in September 2008

ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas

scientific article published on August 2013

Abstract 5493: Genome-wide study of carboplatin and paclitaxel disposition in ovarian cancer patients

Accelerated Barocycler Lysis and Extraction Sample Preparation for Clinical Proteomics by Mass Spectrometry

scientific article published on 28 November 2018

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

scientific article published on 15 June 2017

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

scientific article published on 19 March 2013

Ankyrin repeat domain 1, ANKRD1, a novel determinant of cisplatin sensitivity expressed in ovarian cancer

scientific article

Antiestrogen inhibition of cell cycle progression in breast cancer cells in associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation

scientific article published on 01 December 1995

Aspirin, nonaspirin nonsteroidal anti-inflammatory drugs, acetaminophen and ovarian cancer survival

scientific article published on 07 February 2015

Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors

scientific article

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 30 July 2018

BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

scientific article

Benign serous ovarian tumour: a redefining moment?

scientific article

Carboplatin and paclitaxel interact antagonistically in a megakaryoblast cell line--a potential mechanism for paclitaxel-mediated sparing of carboplatin-induced thrombocytopenia.

scientific article

Caring for women with ovarian cancer in the last year of life: a longitudinal study of caregiver quality of life, distress and unmet needs

scientific article published on 11 January 2014

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.

scientific article published on 4 February 2016

Cell proliferation in the normal mouse mammary gland and inhibition by phenylbutyrate.

scientific article published in October 2002

Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies

scientific article

Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis

scientific article

Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells ⬇️

scientific article published on January 31, 1992

Coping strategies, trajectories, and their associations with patient-reported outcomes among women with ovarian cancer

scientific article published on 12 June 2018

Copy Number Aberrations in Benign Serous Ovarian Tumors: A Case for Reclassification?

scientific article published on 05 October 2011

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

scientific article published on 03 November 2020

DNA of mouse mammary tumor virus-like virus is present in human tumors influenced by hormones

scientific article published in May 2010

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

scientific article

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Dietary folate and related micronutrients, folate-metabolising genes, and ovarian cancer survival

article

Does the primary site really matter? Profiling mucinous ovarian cancers of uncertain primary origin (MO-CUP) to personalise treatment and inform the design of clinical trials

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

scientific article

EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas

scientific article published on 23 June 2017

Erratum: Corrigendum: Whole–genome characterization of chemoresistant ovarian cancer

scientific article published in Nature

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"

scientific article

Evidence against the compartmentation of adenosine kinase and adenosine deaminase activities in human erythrocytes ⬇️

scientific article published on 01 May 1980

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study

scientific article

Expression and tyrosine phosphorylation of EMS1 in human breast cancer cell lines

scientific article published on November 1996

Expression of progesterone receptor A and B isoforms in low-grade endometrial stromal sarcoma

scientific article published in April 2004

Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle

scientific article published on 24 March 2004

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer

scientific article published on 27 November 2019

Focal subnuclear distribution of progesterone receptor is ligand dependent and associated with transcriptional activity.

scientific article published on 4 October 2006

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

scientific article published on 17 December 2018

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

scientific article

Genome-wide association study for ovarian cancer susceptibility using pooled DNA.

scientific article published on 13 July 2012

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver

scientific article published on 14 October 2014

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

scientific article

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

scientific article published on 31 January 2016

Global gene expression profiles of ovarian surface epithelial cells in vivo

scientific article

Going to extremes: determinants of extraordinary response and survival in patients with cancer

scientific article published on 01 June 2019

Helplessness/hopelessness, minimization and optimism predict survival in women with invasive ovarian cancer: a role for targeted support during initial treatment decision-making?

scientific article published on 6 January 2016

High levels of genomic aberrations in serous ovarian cancers are associated with better survival

scientific article

High resolution melting for mutation scanning of TP53 exons 5-8

scientific article

History of Comorbidities and Survival of Ovarian Cancer Patients, Results from the Ovarian Cancer Association Consortium

scientific article published on September 2017

History of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report

scientific article

Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer.

scientific article

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article

IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer

scientific article published on 22 February 2011

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of a Locus Near <i>ULK1</i> Associated With Progression-Free Survival in Ovarian Cancer

publication published on 23 June 2021

Identification of a genetic variant associated with treatment outcome in ovarian cancer: the potential role of cholesterol metabolism as a determinant of response to chemotherapy

Impact of obesity on chemotherapy dosing for women with advanced stage serous ovarian cancer in the Australian Ovarian Cancer Study (AOCS)

article

Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis

scientific article published on 17 February 2014

Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos.

scientific article

Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

scientific article published on 03 February 2009

International network of cancer genome projects

scientific article

Inverse regulation of oestrogen receptor and epidermal growth factor receptor gene expression in MCF-7 breast cancer cells treated with phorbol ester.

scientific article

Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer

scientific article

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin

scientific article

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome

scientific article published on 27 January 2014

MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

scientific article

MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma

scientific article published on 05 October 2005

Medical costs and outcomes for Australian women with ovarian cancer: a patient-level analysis over 2.5 years

scientific article

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

scientific article published in Nature Communications

Modulation of antifolate cytotoxicity by metabolites from dying cells in a lymphocyte clonal assay.

scientific article published on May 1988

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

scientific article published on 19 October 2015

Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer

scientific article published on 20 March 2019

Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.

scientific article published in November 2008

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

scientific article published on 10 June 2009

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer

scientific article published in March 2018

New Approaches to Continuing Medical Education: a QStream (spaced education) Program for Research Translation in Ovarian Cancer

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations

scientific article published on 30 April 2013

Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

scientific article

Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium

scientific article

Overlapping and Distinct Expression of Progesterone Receptors A and B in Mouse Uterus and Mammary Gland during the Estrous Cycle

scientific article published on 15 September 2006

PARAGON (ANZGOG-0903): a phase 2 study of anastrozole in asymptomatic patients with estrogen and progesterone receptor-positive recurrent ovarian cancer and CA125 progression

scientific article published on 01 September 2019

PARAGON: A Phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors

scientific article published on 18 June 2019

Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer

scientific article

Paragon (ANZGOG-0903): Phase 2 Study of Anastrozole in Women With Estrogen or Progesterone Receptor-Positive Platinum-Resistant or -Refractory Recurrent Ovarian Cancer

scientific article published on 12 May 2017

Patterns of chemotherapy treatment for women with invasive epithelial ovarian cancer--a population-based study

scientific article

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients

scientific article

Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium

scientific article

Pre- and post-diagnosis diet quality and ovarian cancer survival

scientific article published on 03 November 2020

Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on 3 January 2017

Prevalence and predictors of insomnia in women with invasive ovarian cancer: anxiety a major factor

scientific article published on 18 June 2009

Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome

scientific article

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

scientific article

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quality of Life and Treatment Response Among Women With Platinum-Resistant Versus Platinum-Sensitive Ovarian Cancer Treated for Progression

Quality of life and treatment response among women with platinum-resistant versus platinum-sensitive ovarian cancer treated for progression: a prospective analysis

scientific article

Rapid fluorometric detection of drug resistant tumour cells.

scientific article published on October 1985

Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium

scientific article

Reducing time to diagnosis does not improve outcomes for women with symptomatic ovarian cancer: a report from the Australian Ovarian Cancer Study Group.

scientific article

Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

scientific article published on 28 July 2020

Response rates to second-line platinum-based therapy in ovarian cancer patients challenge the clinical definition of platinum resistance

scientific article published on 26 May 2018

Scientists and clinicians test their metal-back to the future with platinum compounds

scientific article

Serous ovarian and primary peritoneal cancers: A comparative analysis of clinico-pathological features, molecular subtypes and treatment outcome

scientific article published on 18 July 2016

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Strategies to enable large-scale proteomics for reproducible research

scientific article published on 30 July 2020

Subnuclear distribution of progesterone receptors A and B in normal and malignant endometrium

scientific article published in March 2004

The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function.

scientific article

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro

scientific article published on 18 March 2008

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.

scientific article

The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer.

scientific article published on 25 October 2016

The molecular origin and taxonomy of mucinous ovarian carcinoma

scientific article published on 02 September 2019

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells ⬇️

scientific article published on 01 August 1992

Transducin-Like Enhancer of Split 3 (TLE3) expression is associated with taxane sensitivity in non-serous ovarian carcinoma in a three-cohort study

scientific article published on 12 March 2018

Tumor protein D52 (TPD52) is overexpressed and a gene amplification target in ovarian cancer

scientific article

Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on 28 March 2017

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer

scientific article published on 16 April 2014

Whole-genome characterization of chemoresistant ovarian cancer

scientific article published in May 2015

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 22 March 2023

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