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List of works by Hector Hernandez-Vargas

Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors

scientific article published on 27 February 2015

Asbestos-associated genome-wide DNA methylation changes in lung cancer.

scientific article

Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk.

scientific article published on 26 February 2015

DNA Methylation Analysis from Blood Spots: Increasing Yield and Quality for Genome-Wide and Locus-Specific Methylation Analysis

scientific article published in January 2018

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

scientific article published on 30 March 2016

DNA methylation characteristics of primary melanomas with distinct biological behaviour.

scientific article

Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-β) is associated with a DNA methylome switch.

scientific article

Epigenetic signatures in stem cells and cancer stem cells.

scientific article published on December 2009

Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α

scientific article

Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia

scientific article published on 7 April 2015

Gene expression profiling of breast cancer cells in response to gemcitabine: NF-kappaB pathway activation as a potential mechanism of resistance.

scientific article published on 13 October 2006

Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor

scientific article published on 08 May 2020

Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers.

scientific article published on 18 April 2015

Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes.

scientific article published on 2 November 2015

Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours.

scientific article published on 24 April 2013

Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors

scientific article

Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells.

scientific article published in May 2013

Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5'-DFUR in breast cancer MCF7 cells.

scientific article published on 11 September 2006

Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers

scientific article published on October 1, 2011

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing.

scientific article published on 13 February 2016

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

scientific article published on 11 June 2015

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

scientific article published on 20 August 2019

Integrative genomics identifies gene signature associated with melanoma ulceration.

scientific article

Lowly methylated region analysis identifies EBF1 as a potential epigenetic modifier in breast cancer.

scientific article

Methylation profile in penile carcinoma reveals unique signature relative to surround tissue and HPV status.

scientific article published on 4 April 2013

Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells.

scientific article published on April 2011

MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells

scientific article published on 28 February 2013

Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study

scientific article published on 12 June 2013

Molecular profiling of docetaxel cytotoxicity in breast cancer cells: uncoupling of aberrant mitosis and apoptosis.

scientific article published on 13 November 2006

New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research

scientific article published on 01 August 2011

Novel Predictors of Breast Cancer Survival Derived from miRNA Activity Analysis.

scientific article

Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters

scientific article published on 4 September 2013

Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling

scientific article (publication date: July 2014)

Origin and differentiation of dendritic cells

scientific article published on December 1, 2001

Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury

scientific article published on 12 September 2017

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

scientific article published in 2021

Roadmap for investigating epigenome deregulation and environmental origins of cancer

scientific article published on 13 September 2017

Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation

scientific article

SMAD4 TGF-β-independent function preconditions naive CD8+ T cells to prevent severe chronic intestinal inflammation

scientific article published on 01 April 2022

Stromal-associated cytokines bias the interplay between gene expression and DNA methylation in human breast cancers

scientific article published on 14 December 2019

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

scientific article

TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells.

scientific article published on 20 December 2017

Telling cells how to die: docetaxel therapy in cancer cell lines.

scientific article published on 22 April 2007

The DNA methylome of inflammatory bowel disease (IBD) reflects intrinsic and extrinsic factors in intestinal mucosal cells

scientific article published on 12 April 2020

The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.

scientific article published on 14 January 2013

The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region

scientific article published in Scientific Reports

The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models.

scientific article

Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study

scientific article

Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease.

scientific article published on 10 May 2018

Transposable hypomethylation is associated with metastatic capacity of primary melanomas

scientific article

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas

scientific article published on 05 April 2017

Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines

scientific article

miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival

scientific article published on 21 November 2017