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List of works by Beate Winner

Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity

scientific article

Adult neural precursor cells unaffected in animal models of DYT1 dystonia

scientific article published in November 2009

Adult neurogenesis in neurodegenerative diseases.

scientific article published on April 2015

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

scientific article published on April 2008

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress

scientific article published on 22 February 2017

Caspase inhibition decreases cell death in regions of adult neurogenesis.

scientific article published in August 2005

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

scientific article

Complicated hereditary spastic paraplegia with thin corpus callosum: Variation of phenotypic expression over time

article

Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia

scientific article

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

scientific journal article

Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.

scientific article published in February 2008

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein

scientific article published on 9 October 2015

Doublecortin expression levels in adult brain reflect neurogenesis

scientific article

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia

scientific journal article

EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction.

scientific article

Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia.

scientific article

Further clinical and genetic characterization of SPG11: hereditary spastic paraplegia with thin corpus callosum.

scientific article published in April 2006

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model

scientific article published on 11 March 2016

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

scientific article published on 30 December 2013

Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis

scientific article published in March 2012

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

scientific article

Glyc-oxidized LDL impair endothelial function more potently than oxidized LDL: role of enhanced oxidative stress.

scientific article published in May 1998

Human Wild-Type α-Synuclein Impairs Neurogenesis

article

Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease

scientific article published on 12 May 2014

Identification of a heterozygous genomic deletion in the spatacsin gene in SPG11 patients using high-resolution comparative genomic hybridization.

scientific article

Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis

scientific article published on 9 January 2018

Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.

scientific article

Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein.

scientific article

Impairment of endothelial function induced by glyc-oxidized lipoprotein a [Lp(a)]

scientific article published on 01 November 1998

In Vivo Optical Imaging of Neurogenesis: Watching New Neurons in the Intact Brain

article

In vivo demonstration that alpha-synuclein oligomers are toxic

scientific article

In vivo optical imaging of neurogenesis: watching new neurons in the intact brain

scientific article published in January 2008

Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease

scientific article published on 01 January 2014

Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.

scientific article published on 30 June 2016

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells

scientific article published on 11 July 2014

Kdm6b and Pmepa1 as Targets of Bioelectrically and Behaviorally Induced Activin A Signaling

scientific article published on 28 July 2015

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

scientific article

Long-term course and mutational spectrum of spatacsin-linked spastic paraplegia

scientific article

Mechanisms underlying inflammation in neurodegeneration

scientific article (publication date: 19 March 2010)

Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia

scientific article published on 22 February 2018

Model Testing of PluriTest with Next-Generation Sequencing Data

scientific article

Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

scientific article

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

scientific article published in March 2008

Neurodegenerative disease and adult neurogenesis ⬇️

scientific article published on March 1, 2011

Novel truncating and missense mutations of the KCC3 gene associated with Andermann syndrome.

scientific article

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors

scientific article published on 26 August 2015

Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington's disease

scientific article published on 21 April 2007

Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases.

scientific article

Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease

scientific article published on July 2010

Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb

scientific article published on 24 October 2005

Swiprosin-1/EFhd2 - another piece in the puzzle of tauopathy?

scientific article

Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.

scientific article published in September 2006

The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.

scientific article

The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

scientific article published on 14 April 2017

The Spastic Paraplegia Rating Scale (SPRS): a reliable and valid measure of disease severity.

scientific article published in August 2006

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases.

scientific article published on 27 October 2017

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice

scientific article published on 11 May 2015

Thin corpus callosum and amyotrophy in spastic paraplegia--case report and review of literature

scientific article

Thoracic rat spinal cord contusion injury induces remote spinal gliogenesis but not neurogenesis or gliogenesis in the brain

scientific article

Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS.

scientific article

Transforming growth factor-beta1 is a negative modulator of adult neurogenesis

scientific article

Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification

scientific article published on 19 November 2018

α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy

scientific article

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

scientific article

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

scientific article

β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5.

scientific article published on 14 November 2019

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