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Authors whose works are in public domain in at least one jurisdiction

List of works by Rita De Santis

Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals

scientific article

Anti-ErbB2 immunotherapeutics: struggling to make better antibodies for cancer therapy

scientific article published on 01 January 2020

Anti-proliferative effect of a triazole derivative (ST1959) on LNCaP human prostate cancer cells through down-regulation of cyclin and androgen receptor expression.

scientific article published on January 2011

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation

Antibody-based cancer therapies: back to "polyclonals"?

scientific article published on 17 July 2004

AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.

scientific article

AvidinOX™ for tissue targeted delivery of biotinylated cells.

scientific article published in January 2012

Biochemical and biological characterization of a new oxidized avidin with enhanced tissue binding properties.

scientific article

Characterization of therapeutic protein AvidinOX by an integrated analytical approach.

scientific article published on 22 November 2017

Chemical linkage to injected tissues is a distinctive property of oxidized avidin

scientific article

Clavin, a type-1 ribosome-inactivating protein from Aspergillus clavatus IFO 8605. cDNA isolation, heterologous expression, biochemical and biological characterization of the recombinant protein.

scientific article published on July 1996

Comparative activity of Sant7 and anti-IL-6, IL-6R monoclonal antibodies in a murine model of B-cell lymphoma

scientific article

Correction: Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

scientific article published on 30 March 2018

Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88.

scientific article

Dissecting drug and vehicle metabolic effects in rats by a metabonomic approach.

scientific article published on 30 August 2006

Effect of PTX3 and voriconazole combination in a rat model of invasive pulmonary aspergillosis.

scientific article published on 24 September 2012

Efficacy of PTX3 and posaconazole combination in a rat model of invasive pulmonary aspergillosis

scientific article

Efficacy of a nanocochleate-encapsulated 3,5-diaryl-s-triazole derivative in a murine model of graft-versus-host disease.

scientific article published in July 2008

Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab

scientific article published on October 2014

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT)

scientific article published on 06 June 2006

Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

scientific article published on 3 January 2018

Expansion of granulocyte colony-stimulating factor/chemotherapy-mobilized CD34+ hematopoietic progenitors: role of granulocyte-macrophage colony-stimulating factor/erythropoietin hybrid protein (MEN11303) and interleukin-15

scientific article published on 01 March 1999

Expression and characterization of a mouse/human chimeric antibody specific for EGF receptor

scientific article published on 01 November 1996

Growth inhibition of human ovarian carcinoma by a novel AvidinOX-anchored biotinylated camptothecin derivative

scientific article published on 15 September 2018

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo

scientific article published on 27 July 2018

Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

scientific article published on 12 February 2022

Identification and refinement of a peptide affinity ligand with unique specificity for a monoclonal anti-tenascin-C antibody by screening of a phage display library.

scientific article published on 18 January 2006

Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer.

scientific article published on 7 November 2015

Intraoperative avidination for radionuclide therapy: a prospective new development to accelerate radiotherapy in breast cancer

scientific article

Intraoperative avidination for radionuclide treatment as a radiotherapy boost in breast cancer: results of a phase II study with (90)Y-labeled biotin.

scientific article published on 4 September 2009

Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody.

scientific article published on April 2006

Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody

scientific article

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

scientific article

OXavidin for tissue targeting biotinylated therapeutics. ⬇️

scientific article

Overproduction of soluble, extracellular cytotoxin α-sarcin inEscherichia coli ⬇️

scientific article published on April 1, 1998

PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation

scientific article published on 13 July 2006

Pharmacokinetic and immunogenic behavior of three recombinant human GM-CSF-EPO hybrid proteins in cynomolgus monkeys

scientific article published on 01 October 1998

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

scientific article published on 25 August 2010

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

scientific article published on 04 June 2007

Preclinical Pharmacology and Safety of a Novel Avidin Derivative for Tissue‐Targeted Delivery of Radiolabelled Biotin ⬇️

scientific article published on April 25, 2011

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

scientific article published on March 2015

Pretargeted antibody-guided radioimmunotherapy in a child affected by resistant anaplastic large cell lymphoma

scientific article published on 26 July 2007

Purification and characterization of two recombinant human granulocyte colony-stimulating factor glycoforms. Pharmacokinetic and activity studies of single-dose administration in mice.

scientific article published on April 1999

Radionuclide Therapy of Unresectable Tumors with AvidinOX and (90)Y-biotinDOTA: Tongue Cancer Paradigm

scientific article

Role of Cross-Linking Agents in Determining the Biochemical and Pharmacokinetic Properties of Mgr6−Clavin Immunotoxins

scientific article published on 01 May 1998

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

scientific article

Simultaneous display of two large proteins on the head and tail of bacteriophage lambda

scientific article

Structural characterization and independent folding of a chimeric glycoprotein comprising granulocyte-macrophage colony stimulating factor and erythropoietin sequences

scientific article published on August 1, 1998

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization

scientific article published on 25 January 2008

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

scientific article published in September 2006

The fusion protein MEN 11303 (granulocyte-macrophage colony stimulating factor/erythropoietin) acts as a potent inducer of erythropoiesis.

scientific article

Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans ⬇️

scientific article published on September 23, 2010

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance

scientific article published on 26 October 2015

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.

scientific article

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells.

scientific article

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