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List of works by Lee H Wong

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

scientific article

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

scientific journal article

Active transcription and essential role of RNA polymerase II at the centromere during mitosis

scientific article published on 20 January 2012

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

scientific journal article

Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice

scientific article published on 22 November 2004

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

scientific article published on 10 October 2017

BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints

scientific article

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

scientific article

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

scientific article

Centromere on the move.

scientific article

Centromere protein b-null mice display decreasing reproductive performance through successive generations of breeding due to diminishing endometrial glands.

scientific article published in March 2004

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated

scientific article (publication date: 26 July 2002)

Centromeric chromatin pliability and memory at a human neocentromere.

scientific article

Compromised Telomeric Heterochromatin Promotes ALTernative Lengthening of Telomeres.

scientific article published on 4 March 2016

Conditional allelic replacement applied to genes encoding the histone variant H3.3 in the mouse

scientific article published on 7 February 2013

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

scientific article published in May 2001

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice

scientific journal article

Detection of cryptic pathogenic copy number variations and constitutional loss of heterozygosity using high resolution SNP microarray analysis in 117 patients referred for cytogenetic analysis and impact on clinical practice.

scientific article

Epigenetic Regulation of Telomere Chromatin Integrity in Pluripotent Embryonic Stem Cells ⬇️

scientific article published on October 1, 2010

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

scientific article

Evolutionary dynamics of transposable elements at the centromere

scientific article

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

scientific article

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

scientific article published on 23 October 2015

High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting

scientific article published on 10 July 2014

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells ⬇️

scientific article published on 05 February 2009

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

scientific article

Human centromere repositioning "in progress"

scientific article

IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs.

scientific article published on June 1998

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

scientific article published in Nature Communications

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

scientific article published on November 1997

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1.

scientific article published on 21 March 2002

LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin

scientific article

Lessons from neocentromeres

scientific article published on 01 June 2011

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

scientific article published on 10 May 2021

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

scientific article

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells

scientific article

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells

scientific journal article

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.

scientific article published on 24 March 2017

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

scientific article

Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc

scientific article (publication date: 15 September 2002)

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

scientific article published on 18 April 2018

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

scientific article

The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals

scientific article

Transcription in the maintenance of centromere chromatin identity

scientific article

Transcription within a functional human centromere

scientific article

UBF levels determine the number of active ribosomal RNA genes in mammals

scientific journal article

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere

scientific article

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