List of works - Nick Wong

A case-sibling assessment of the association between skin pigmentation and other vitamin D-related factors and type 1 diabetes mellitus

scientific article published on 21 May 2009

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma

scientific article

A novel role for Lyl1 in primitive erythropoiesis

scientific article published on 11 October 2018

A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors

scientific article

Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis.

scientific article published on October 2008

Atypical Spitzoid neoplasms: a review of potential markers of biological behavior including sentinel node biopsy.

scientific article published on October 2014

BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints

scientific article

Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes

scientific article

DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta

scientific article

Effects of scaffold/matrix alteration on centromeric function and gene expression.

scientific article published on 25 June 2004

Epigenetic deregulation in pediatric acute lymphoblastic leukemia.

scientific article

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

scientific article published on 20 July 2010

Evaluation of microRNA expression in patient bone marrow aspirate slides.

scientific article

Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia

article

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat

scientific article

Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA.

scientific article published on 29 April 2013

FXN methylation predicts expression and clinical outcome in Friedreich ataxia.

scientific article published in April 2012

From reads to insight: a hitchhiker's guide to ATAC-seq data analysis

scientific article published on 03 February 2020

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

scientific article published on 18 July 2016

Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1.

scientific article

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies

scientific article published on 14 September 2011

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome

scientific article

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

scientific article

Methylation of the adenomatous polyposis coli (APC) gene in human placenta and hypermethylation in choriocarcinoma cells.

scientific article

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells

scientific article

Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears

scientific article

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

scientific article

Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray.

scientific article published on 12 March 2018

Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

scientific article

Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

scientific article published on 22 January 2014

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

scientific article published in Nature Communications

Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblasts.

scientific article

Specific-site methylation of tumour suppressor ANKRD11 in breast cancer

scientific article published on 24 April 2012

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance

scientific article

The changing landscape of research funding: challenges for mid-career researchers

scientific article published on 28 August 2019

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.

scientific article published on 15 December 2017

The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array

scientific article

Validation of DNA methylation biomarkers for diagnosis of acute lymphoblastic leukemia.

scientific article

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere

scientific article

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

scientific article

Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.

scientific article published on 02 February 2011

List of works by Nick Wong

A case-sibling assessment of the association between skin pigmentation and other vitamin D-related factors and type 1 diabetes mellitus

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma

A novel role for Lyl1 in primitive erythropoiesis

A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors

Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis.

Atypical Spitzoid neoplasms: a review of potential markers of biological behavior including sentinel node biopsy.

BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints

Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes

DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta

Effects of scaffold/matrix alteration on centromeric function and gene expression.

Epigenetic deregulation in pediatric acute lymphoblastic leukemia.

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

Evaluation of microRNA expression in patient bone marrow aspirate slides.

Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat

Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA.

FXN methylation predicts expression and clinical outcome in Friedreich ataxia.

From reads to insight: a hitchhiker's guide to ATAC-seq data analysis

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1.

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

Methylation of the adenomatous polyposis coli (APC) gene in human placenta and hypermethylation in choriocarcinoma cells.

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells

Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray.

Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblasts.

Specific-site methylation of tumour suppressor ANKRD11 in breast cancer

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance

The changing landscape of research funding: challenges for mid-career researchers

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.

The use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array

Validation of DNA methylation biomarkers for diagnosis of acute lymphoblastic leukemia.

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.