List of works by Dominic De Nardo

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy

scientific article published on 06 July 2018

A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

scientific article

ATF3 Is a Key Regulator of Macrophage IFN Responses

scientific article published on 28 September 2015

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

scientific article published on 25 May 2015

Activation of the Innate Immune Receptors: Guardians of the Micro Galaxy : Activation and Functions of the Innate Immune Receptors.

scientific article published in January 2017

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

scientific article published on 17 January 2017

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface

scholarly article by Fiona Moghaddas et al published December 2018 in The Journal of Allergy and Clinical Immunology

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use.

scientific article published on 05 January 2016

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

scientific article

Deficiency in coatomer complex I causes aberrant activation of STING signalling

scientific article published on 28 April 2022

Down-regulation of IRAK-4 is a component of LPS- and CpG DNA-induced tolerance in macrophages

scientific article published in February 2009

Emerging Concepts in Innate Immunity.

scientific article published in January 2018

Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence

scientific article published on 01 January 2016

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

scientific article

Generation of Innate Immune Reporter Cells Using Retroviral Transduction.

scientific article published in January 2018

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.

scientific article

Immortalization of Murine Bone Marrow-Derived Macrophages

scientific article published on 01 January 2018

Innate immunity

scientific article published on 01 February 2014

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

scientific article

Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

scientific article published in Journal of Biological Chemistry

Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence.

scientific article

Molecular and spatial mechanisms governing STING signalling

scientific article published on 25 November 2020

Optimization of transcription factor binding map accuracy utilizing knockout-mouse models

scientific article

Regulation of IRAK-1 activation by its C-terminal domain.

scientific article

The inflammasomes and autoinflammatory syndromes.

scientific article published on 19 November 2014

Toll-like receptors: Activation, signalling and transcriptional modulation.

scientific article published on 03 April 2015

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

scientific article

Understanding early TLR signaling through the Myddosome

scientific article published on 26 September 2018

Whole exome sequencing in systemic juvenile idiopathic arthritis.

scientific article published on 28 September 2015

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