List of works - Abhay Kotecha

A supramolecular assembly mediates lentiviral DNA integration ⬇️

scientific article published on January 2017

Age-dependent formation of TMEM106B amyloid filaments in human brains

scientific article published in 2022

Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation.

scientific article published on 22 March 2016

Assembly intermediates of orthoreovirus captured in the cell

scientific article published on 07 September 2020

CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome

scientific article

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate

scientific article published in Scientific Reports

Cryo-EM structures of amyloid-β 42 filaments from human brains

scientific article published in 2022

Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate

scientific article

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

scientific article

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

scientific article published on 19 November 2012

Evolution of low-light adapted peripheral light-harvesting complexes in strains of Rhodopseudomonas palustris

scientific article published on 19 December 2012

Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis

scientific article published on 8 December 2012

GABA receptor signalling mechanisms revealed by structural pharmacology

scientific article published on 02 January 2019

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays

scientific article published in PLoS ONE

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

scientific article published on 07 January 2020

Heteromeric GABAAreceptor structures in positively-modulated active states

High-speed fixed-target serial virus crystallography ⬇️

scientific article

In situ macromolecular crystallography using microbeams

scientific article published on 17 April 2012

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy

scientific article published on 23 October 2017

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

scientific article

Machining protein microcrystals for structure determination by electron diffraction

article published in the Proceedings of the National Academy of Sciences of the United States of America

Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine ⬇️

scientific article published on 15 August 2017

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site

scientific article published on 10 January 2017

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

scientific article

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

scientific article

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability

scientific article published on 15 March 2017

Single-particle cryo-EM at atomic resolution

scientific article published on 21 October 2020

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

scientific article published on 16 October 2020

Structural basis of second-generation HIV integrase inhibitor action and viral resistance

scientific article

Structure of Ljungan virus provides insight into genome packaging of this picornavirus.

scientific article

Structure of human Aichi virus and implications for receptor binding

scientific article

Structure-based classification of tauopathies

scientific article published on 29 September 2021

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

scientific article

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

scientific article published on 22 September 2017

Structures of α-synuclein filaments from human brains with Lewy pathology

scientific article published in 2022

Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses

scientific article published on 29 September 2020

The B Cell Response to Foot-and-Mouth Disease Virus in Cattle following Sequential Vaccination with Multiple Serotypes

scientific article published on 22 February 2017

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

scientific article published on 19 February 2019

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2 ⬇️

scientific article published on 10 December 2018

Universal detection of foot and mouth disease virus based on the conserved VP0 protein

article by Silvia Loureiro et al published 25 July 2018 in Wellcome Open Research

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants

scientific article published on 22 December 2023

List of works by Abhay Kotecha

A supramolecular assembly mediates lentiviral DNA integration ⬇️

Age-dependent formation of TMEM106B amyloid filaments in human brains

Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation.

Assembly intermediates of orthoreovirus captured in the cell

CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate

Cryo-EM structures of amyloid-β 42 filaments from human brains

Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

Evolution of low-light adapted peripheral light-harvesting complexes in strains of Rhodopseudomonas palustris

Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis

GABA receptor signalling mechanisms revealed by structural pharmacology

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

Heteromeric GABAAreceptor structures in positively-modulated active states

High-speed fixed-target serial virus crystallography ⬇️

In situ macromolecular crystallography using microbeams

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes

Machining protein microcrystals for structure determination by electron diffraction

Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine ⬇️

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site

Rational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine Antigen

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability

Single-particle cryo-EM at atomic resolution

Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

Structural basis of second-generation HIV integrase inhibitor action and viral resistance

Structure of Ljungan virus provides insight into genome packaging of this picornavirus.

Structure of human Aichi virus and implications for receptor binding

Structure-based classification of tauopathies

Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

Structures of α-synuclein filaments from human brains with Lewy pathology

Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses

The B Cell Response to Foot-and-Mouth Disease Virus in Cattle following Sequential Vaccination with Multiple Serotypes

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2 ⬇️

Universal detection of foot and mouth disease virus based on the conserved VP0 protein

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants