List of works by Pierre Bruhns

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

scholarly article by Diana Ordoñez-Rueda et al published September 2012 in European Journal of Immunology

A strain of Lactobacillus casei inhibits the effector phase of immune inflammation

scientific article published on 01 August 2011

An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIa Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages

scientific article published on 27 March 2019

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

scientific article published on 01 July 2019

An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence

scientific article published on 06 November 2019

Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant

scientific article published on 07 April 2022

Author Correction: High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

scientific article published on 22 May 2020

Autonomous phagosomal degradation and antigen presentation in dendritic cells

scientific article

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease

scientific article

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

scientific article

Cutting Edge: Neutralizing Public Antibody Responses Are an Ancient Form of Defense Conserved in Fish and Mammals

scientific article published on 15 July 2021

Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis

scientific article published on 19 January 2011

Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma.

scientific article published on 12 November 2012

Cutting edge: intravenous Ig inhibits invariant NKT cell-mediated allergic airway inflammation through FcγRIIIA-dependent mechanisms.

scientific article published on 11 February 2011

Differential recruitment of activating and inhibitory Fc gamma RII during phagocytosis.

scientific article

High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

scientific article published on 30 March 2020

Human IgG1 antibodies suppress angiogenesis in a target-independent manner

scientific article published on 28 January 2016

IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

scientific article published on 12 June 2017

IgG subclasses determine pathways of anaphylaxis in mice.

scientific article published on 26 April 2016

Inhibitory IgG Receptor-Expressing Cells: The Must-Have Accessory for Anti-CD40 Immunomodulatory mAb Efficacy.

scientific article published in June 2016

Innate Immune Basis for Rift Valley Fever Susceptibility in Mouse Models.

scientific article published on 2 August 2017

Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE

scientific article published on 07 December 2018

Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization

scientific article published on 17 October 2014

In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models

scientific article

Ligand binding but undetected functional response of FcR after their capture by T cells via trogocytosis.

scientific article published on 19 October 2009

Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions.

scientific article published on 10 October 2017

Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection

scientific article published on 22 November 2019

Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a+ CD4+ T Cells From Early HIV Infection to Effective cART.

scientific article published on 4 June 2018

Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice.

scientific article published on 24 August 2016

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells

scientific article

Mouse and human FcR effector functions

scientific article

Mouse and human neutrophils induce anaphylaxis.

scientific article

Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling

scientific article published on 01 October 2000

Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells

scientific article

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.

scientific article published on 6 April 2017

Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions.

scientific article published on 26 March 2013

Neutrophils mediate antibody-induced antitumor effects in mice.

scientific article published on 26 August 2013

Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis

scientific article published on 17 July 2016

Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia

scientific article

Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis

scientific article published on 01 April 2018

Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites

scientific article published on 18 July 2016

Regulation of allergy by Fc receptors.

scientific article

Shaping mycolactone for therapeutic use against inflammatory disorders

scientific article published on May 2015

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

scientific article

Signal regulatory proteins negatively regulate immunoreceptor-dependent cell activation.

scientific article

Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring.

scientific article published on 11 September 2017

The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcgammaRIIB and is mandatory for negative regulation of B cell activation

scientific article published on 19 December 2005

The function of Fcγ receptors in dendritic cells and macrophages

scientific article published on 21 January 2014

The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy

scientific article

The pseudo-immunoreceptor tyrosine-based activation motif of CD5 mediates its inhibitory action on B-cell receptor signaling

scientific article published on 01 January 2000

The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling

scientific article published on 7 September 2016

Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap

scientific article

mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants

scientific article published on 21 September 2021

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