List of works - Rita Carsetti

A metaproteomic pipeline to identify newborn mouse gut phylotypes

scientific article published on 29 October 2013

A multiple retinoic acid antagonist induces conotruncal anomalies, including transposition of the great arteries, in mice

scientific article published on 01 July 2006

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

scientific article published on 10 October 2019

A novel form of non-X-linked hyperigm associated with growth and pubertal disturbances and with lymphoma development

scientific article published in March 2006

A novel immunodeficiency characterized by the exclusive presence of transitional B cells unresponsive to CpG

scientific article published on 20 February 2007

A novel mouse thymocyte antigen (F3Ag): down-regulation during the CD4+CD8+ double-positive stage indicates positive selection

scientific article published on 01 January 1996

A refined approach to detect and measure minimal residual disease in childhood acute myeloid leukemia by flow cytometry

scientific article published on 19 February 2014

A role for immunoglobulin D: interference with tolerance induction

scientific article published on 01 January 1993

Abatacept (cytotoxic T lymphocyte antigen 4-immunoglobulin) improves B cell function and regulatory T cell inhibitory capacity in rheumatoid arthritis patients non-responding to anti-tumour necrosis factor-α agents

scientific article published on 01 September 2014

Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain

scientific article published on January 2003

Additional maternal and nonmaternal factors contribute to microbiota shaping in newborns.

scientific article published on 27 September 2010

Anhidrotic ectodermal dysplasia: A new mutation ⬇️

scientific article published on July 16, 2013

Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome

scientific article published on 07 May 2019

B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome ⬇️

scientific article published on 13 November 2015

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

scientific article

B cell modulation strategies in autoimmunity: the SLE example.

scientific article published on January 2011

B cell phenotype in pediatric idiopathic nephrotic syndrome

scientific article published on 28 September 2018

B cells from nuclear factor kB essential modulator deficient patients fail to differentiate to antibody secreting cells in response to TLR9 ligand.

scientific article published on 22 August 2015

B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients.

scientific article

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

scientific article published on 22 June 2018

Development and function of the mammalian spleen.

scientific article published on February 2007

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity

scientific article published on 21 March 2019

Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation

scientific article published on 18 November 2016

Dysregulated miR-155 and miR-125b Are Related to Impaired B-cell Responses in Down Syndrome

article

Early-life gut microbiota under physiological and pathological conditions: the central role of combined meta-omics-based approaches.

scientific article

Effects of exposure to gradient magnetic fields emitted by nuclear magnetic resonance devices on clonogenic potential and proliferation of human hematopoietic stem cells.

scientific article published on 15 March 2016

Evaluating B-cells: from bone marrow precursors to antibody-producing cells.

scientific article published in January 2013

Folic acid and methionine in the prevention of teratogen-induced congenital defects in mice.

scientific article published on 15 April 2008

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes

scientific journal article

Generation of switched memory B cells in response to vaccination in Down syndrome children and their siblings

scientific article published on 27 October 2015

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders

scientific article published on 28 May 2014

Hematopoietic activity in putative mouse primordial germ cell populations.

scientific article published on 12 February 2015

Hepatitis B specific T cell immunity induced by primary vaccination persists independently of the protective serum antibody level ⬇️

scientific article published on November 19, 2012

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

scientific article

Heterotaxy syndrome with and without spleen: Different infection risk and management.

scientific article

High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.

scientific article

Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events.

scientific article published on 16 November 2016

Humoral immune responses and CD27+ B cells in children with DiGeorge syndrome (22q11.2 deletion syndrome)

article

Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells

scientific article

Immunoglobulin-mediated signal transduction in B cells from CD45-deficient mice

scientific article

Impact of a mixed bacterial lysate (OM-85 BV) on the immunogenicity, safety and tolerability of inactivated influenza vaccine in children with recurrent respiratory tract infection

scientific article published on 26 March 2014

Impairment of the antipolysaccharide response in splenectomized patients is due to the lack of immunoglobulin M memory B cells

scientific article published in April 2006

Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin alpha4beta7-positive T cells in blood

scientific article

Increased risk of invasive meningococcal disease, pregnancy, and confounding

scientific article published on 01 September 2005

Increased serum IgM, immunodeficiency, and autoimmunity: A clinical series

scientific article published on December 2015

Induction of CD14 expression in Lpsn, Lpsd and tumor necrosis factor receptor-deficient mice

scientific article published on 01 November 1996

Induction of regulatory T cells after prophylactic treatment with photopheresis in renal transplant recipients

scientific article published on 01 May 2007

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections.

scientific article published on 12 July 2017

Inhibition of B-cell proliferation and antibody production by mesenchymal stromal cells is mediated by T cells.

scientific article

Long-term survival and phenotypic spectrum in heterotaxy syndrome: A 25-year follow-up experience

scientific article published on 01 October 2018

Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency.

scientific article

Mechanistic associations of a mild phenotype of immunodysregulation, polyendocrinopathy, enteropathy, x-linked syndrome

scientific article published on 01 May 2006

Memory B-cell subsets as a predictive marker of outcome in hypogammaglobulinemia during infancy.

scientific article published on 25 May 2007

Metaproteomic investigation to assess gut microbiota shaping in newborn mice: A combined taxonomic, functional and quantitative approach

scientific article published on 15 May 2019

Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro

scientific article published on 31 July 2014

Molecular mimicry of the antigen receptor signalling motif by transmembrane proteins of the Epstein-Barr virus and the bovine leukaemia virus.

scientific article published in June 1993

Monitoring Perinatal Gut Microbiota in Mouse Models by Mass Spectrometry Approaches: Parental Genetic Background and Breastfeeding Effects

scientific article

Novel STAT1 gain-of-function mutation and suppurative infections.

scientific article

Parents as source of pertussis transmission in hospitalized young infants

scientific article published on 10 September 2016

Pathogen- or damage-associated molecular patterns during nonalcoholic fatty liver disease development

scientific article published on 28 October 2011

Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease

scientific article published on 01 November 2010

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

scientific article published on 25 August 2010

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

scientific article published on 04 June 2007

Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities

scientific article published on 16 May 2014

Post-splenectomy and hyposplenic states.

scientific article

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

scientific article published on 16 July 2019

Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells

scientific article published on 15 September 2017

Purification and immunophenotypic characterization of murine MZ and T2-MZP cells.

scientific article published in January 2014

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells

scientific article published on 10 July 2018

Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome.

scientific article

Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers.

scientific article published on 5 November 2014

Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function

scientific article published on 09 November 2010

Severe Toxoplasma gondii infection in a member of a NFKB2-deficient family with T and B cell dysfunction.

scientific article published on 14 September 2017

Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization.

scientific article

Spleen development is modulated by neonatal gut microbiota

article

Splenic function and IgM-memory B cells in Crohn's disease patients treated with infliximab.

scientific article published in May 2008

Splenic hypofunction and the spectrum of autoimmune and malignant complications in celiac disease.

scientific article

Switched Memory B Cells Are Increased In Oligoarticular And Polyarticular Juvenile Idiopathic Arthritis And Their Change Over Time Is Related To Response To TNF Inhibitors.

scientific article published on 5 January 2018

TLR ligation triggers somatic hypermutation in transitional B cells inducing the generation of IgM memory B cells.

scientific article published on 15 November 2010

The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity.

scientific article published on 13 November 2017

The development of B cells in the bone marrow is controlled by the balance between cell-autonomous mechanisms and signals from the microenvironment.

scientific article published on January 2000

The immunological effects of extracorporeal photopheresis unraveled: induction of tolerogenic dendritic cells in vitro and regulatory T cells in vivo

scientific article published on 01 April 2005

The loss of IgM memory B cells correlates with clinical disease in common variable immunodeficiency.

scientific article published in February 2005

The possible implication of the S250C variant of the autoimmune regulator protein in a patient with autoimmunity and immunodeficiency: in silico analysis suggests a molecular pathogenic mechanism for the variant

scientific article published on 25 July 2014

Why do we need IgM memory B cells?

scientific article published on 06 May 2013

List of works by Rita Carsetti

A metaproteomic pipeline to identify newborn mouse gut phylotypes

A multiple retinoic acid antagonist induces conotruncal anomalies, including transposition of the great arteries, in mice

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

A novel form of non-X-linked hyperigm associated with growth and pubertal disturbances and with lymphoma development

A novel immunodeficiency characterized by the exclusive presence of transitional B cells unresponsive to CpG

A novel mouse thymocyte antigen (F3Ag): down-regulation during the CD4+CD8+ double-positive stage indicates positive selection

A refined approach to detect and measure minimal residual disease in childhood acute myeloid leukemia by flow cytometry

A role for immunoglobulin D: interference with tolerance induction

Abatacept (cytotoxic T lymphocyte antigen 4-immunoglobulin) improves B cell function and regulatory T cell inhibitory capacity in rheumatoid arthritis patients non-responding to anti-tumour necrosis factor-α agents

Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain

Additional maternal and nonmaternal factors contribute to microbiota shaping in newborns.

Anhidrotic ectodermal dysplasia: A new mutation ⬇️

Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome

B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome ⬇️

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

B cell modulation strategies in autoimmunity: the SLE example.

B cell phenotype in pediatric idiopathic nephrotic syndrome

B cells from nuclear factor kB essential modulator deficient patients fail to differentiate to antibody secreting cells in response to TLR9 ligand.

B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients.

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

Development and function of the mammalian spleen.

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity

Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation

Dysregulated miR-155 and miR-125b Are Related to Impaired B-cell Responses in Down Syndrome

Early-life gut microbiota under physiological and pathological conditions: the central role of combined meta-omics-based approaches.

Effects of exposure to gradient magnetic fields emitted by nuclear magnetic resonance devices on clonogenic potential and proliferation of human hematopoietic stem cells.

Evaluating B-cells: from bone marrow precursors to antibody-producing cells.

Folic acid and methionine in the prevention of teratogen-induced congenital defects in mice.

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes

Generation of switched memory B cells in response to vaccination in Down syndrome children and their siblings

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders

Hematopoietic activity in putative mouse primordial germ cell populations.

Hepatitis B specific T cell immunity induced by primary vaccination persists independently of the protective serum antibody level ⬇️

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

Heterotaxy syndrome with and without spleen: Different infection risk and management.

High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.

Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events.

Humoral immune responses and CD27+ B cells in children with DiGeorge syndrome (22q11.2 deletion syndrome)

Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells

Immunoglobulin-mediated signal transduction in B cells from CD45-deficient mice

Impact of a mixed bacterial lysate (OM-85 BV) on the immunogenicity, safety and tolerability of inactivated influenza vaccine in children with recurrent respiratory tract infection

Impairment of the antipolysaccharide response in splenectomized patients is due to the lack of immunoglobulin M memory B cells

Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin alpha4beta7-positive T cells in blood

Increased risk of invasive meningococcal disease, pregnancy, and confounding

Increased serum IgM, immunodeficiency, and autoimmunity: A clinical series

Induction of CD14 expression in Lpsn, Lpsd and tumor necrosis factor receptor-deficient mice

Induction of regulatory T cells after prophylactic treatment with photopheresis in renal transplant recipients

Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections.

Inhibition of B-cell proliferation and antibody production by mesenchymal stromal cells is mediated by T cells.

Long-term survival and phenotypic spectrum in heterotaxy syndrome: A 25-year follow-up experience

Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency.

Mechanistic associations of a mild phenotype of immunodysregulation, polyendocrinopathy, enteropathy, x-linked syndrome

Memory B-cell subsets as a predictive marker of outcome in hypogammaglobulinemia during infancy.

Metaproteomic investigation to assess gut microbiota shaping in newborn mice: A combined taxonomic, functional and quantitative approach

Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro

Molecular mimicry of the antigen receptor signalling motif by transmembrane proteins of the Epstein-Barr virus and the bovine leukaemia virus.

Monitoring Perinatal Gut Microbiota in Mouse Models by Mass Spectrometry Approaches: Parental Genetic Background and Breastfeeding Effects

Novel STAT1 gain-of-function mutation and suppurative infections.

Parents as source of pertussis transmission in hospitalized young infants

Pathogen- or damage-associated molecular patterns during nonalcoholic fatty liver disease development

Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities

Post-splenectomy and hyposplenic states.

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells

Purification and immunophenotypic characterization of murine MZ and T2-MZP cells.

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells

Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome.

Repeated vaccinations do not improve specific immune defenses against Hepatitis B in non-responder health care workers.

Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function

Severe Toxoplasma gondii infection in a member of a NFKB2-deficient family with T and B cell dysfunction.

Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization.

Spleen development is modulated by neonatal gut microbiota

Splenic function and IgM-memory B cells in Crohn's disease patients treated with infliximab.

Splenic hypofunction and the spectrum of autoimmune and malignant complications in celiac disease.

Switched Memory B Cells Are Increased In Oligoarticular And Polyarticular Juvenile Idiopathic Arthritis And Their Change Over Time Is Related To Response To TNF Inhibitors.

TLR ligation triggers somatic hypermutation in transitional B cells inducing the generation of IgM memory B cells.