List of works - Claude Chelala

The BioMart community portal: an innovative alternative to large, centralized data repositories

scientific article (publication date: July 2015)

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

scientific article published on 22 December 2013

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

scientific article

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

scientific article

Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

scientific article published on 21 May 2006

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

scientific article published on 25 July 2013

SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms.

scientific article published on 19 December 2008

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression

scientific article published on 24 June 2011

BioMart Central Portal: an open database network for the biological community

scientific article

EZH2 mutations are frequent and represent an early event in follicular lymphoma

scientific article published on 19 September 2013

SNPnexus: a web server for functional annotation of novel and publicly known genetic variants (2012 update).

scientific article

Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes

scientific article

Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia

scientific article published on 19 May 2008

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

scientific article published on 21 December 2015

S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

scientific article published on July 2007

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

scientific article published on 27 November 2013

Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia

article published in 2008

Therapeutic targeting of integrin αvβ6 in breast cancer

scientific article

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

scientific article

A practical guide for the functional annotation of genetic variations using SNPnexus

scientific article published on 8 February 2013

Disease evolution and outcomes in familial AML with germline CEBPA mutations

scientific article published on 10 July 2015

Genome-wide analysis of pancreatic cancer using microarray-based techniques

scientific article

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

scientific article published on 25 August 2016

Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets

scientific article

PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits

scientific article published on 01 February 2007

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.

scientific article published on 10 June 2016

Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma

scientific article

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

scientific article

The pancreatic expression database: recent extensions and updates

scientific article

Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation.

scientific article published on January 2007

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells

scientific article

Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion

scientific article published on 21 February 2011

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma

scientific article published on 8 June 2016

The Pancreatic Expression database: 2011 update

scientific article

CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells

scientific article published on June 2009

Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease

scientific article published on 5 February 2016

Online resources of cancer data: barriers, benefits and lessons

scientific article (publication date: 2011)

Identification of ZDHHC14 as a novel human tumour suppressor gene.

scientific article published on 8 February 2014

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

scientific article

Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis?

scientific article

Molecular analysis of precursor lesions in familial pancreatic cancer

scientific article

Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer

scientific article

Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1.

scientific article published on 20 July 2016

p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker

scientific article

Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts

scientific article published on 17 November 2016

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

scientific article published on 11 February 2012

Gene expression profiling of breast cancer in Lebanese women

scientific article

SEARCHBreast: a new resource to locate and share surplus archival material from breast cancer animal models to help address the 3Rs.

scientific article published on 15 April 2016

Using BioMart as a framework to manage and query pancreatic cancer data.

scientific article

O-miner: an integrative platform for automated analysis and mining of -omics data.

scientific article

List of works by Claude Chelala

The BioMart community portal: an innovative alternative to large, centralized data repositories

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms.

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression

BioMart Central Portal: an open database network for the biological community

EZH2 mutations are frequent and represent an early event in follicular lymphoma

SNPnexus: a web server for functional annotation of novel and publicly known genetic variants (2012 update).

Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes

Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia

Therapeutic targeting of integrin αvβ6 in breast cancer

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

A practical guide for the functional annotation of genetic variations using SNPnexus

Disease evolution and outcomes in familial AML with germline CEBPA mutations

Genome-wide analysis of pancreatic cancer using microarray-based techniques

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets

PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.

Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

The pancreatic expression database: recent extensions and updates

Identification of genetic alterations in pancreatic cancer by the combined use of tissue microdissection and array-based comparative genomic hybridisation.

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells

Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma

The Pancreatic Expression database: 2011 update

CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells

Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease

Online resources of cancer data: barriers, benefits and lessons

Identification of ZDHHC14 as a novel human tumour suppressor gene.

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis?

Molecular analysis of precursor lesions in familial pancreatic cancer

Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer

Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1.

p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker

Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts

S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells.

Gene expression profiling of breast cancer in Lebanese women

SEARCHBreast: a new resource to locate and share surplus archival material from breast cancer animal models to help address the 3Rs.

Using BioMart as a framework to manage and query pancreatic cancer data.

O-miner: an integrative platform for automated analysis and mining of -omics data.