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List of works by Enric Domingo

'Toxgnostics': an unmet need in cancer medicine

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

scientific article

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

article

A study of genomic instability in early preneoplastic colonic lesions ⬇️

scientific article published on December 17, 2012

Acute absolute vasodilatation is associated with a lower vascular wall stiffness in pulmonary arterial hypertension

scientific article published on 23 July 2011

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

scientific article published on 19 September 2016

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

scientific article

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

scientific article published on 19 February 2019

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

scientific article

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

scientific article published on 25 January 2010

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

scientific article published on 16 December 2007

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

scientific article

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

scientific article

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer

scientific article

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

scientific article

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

scientific article

Guidelines for using sigQC for systematic evaluation of gene signatures

scientific article published on 10 April 2019

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

scientific article published on 20 July 2020

Impairment of pulmonary vascular reserve and right ventricular systolic reserve in pulmonary arterial hypertension

scientific article

In-depth clinical and biological exploration of DNA Damage Immune Response (DDIR) as a biomarker for oxaliplatin use in colorectal cancer

scientific article published on 07 October 2020

Is sidedness prognostically important across all stages of colorectal cancer?

scientific article published on 01 November 2016

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

scientific article published on 14 January 2011

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

article

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

scientific article

New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension.

scientific article published on 12 March 2009

Pharmacoproteomic characterisation of human colon and rectal cancer.

scientific article published on 3 November 2017

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

article

Replication stress links structural and numerical cancer chromosomal instability

scientific article published on February 2013

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

scientific article published on 8 December 2017

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

scientific article published on 20 July 2016

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

scientific article published on 17 September 2013

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

scientific article published on 09 March 2020

The evolutionary landscape of colorectal tumorigenesis ⬇️

scientific article published on 31 August 2018

The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer

scientific article published on 19 May 2020

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

scientific article published on 02 August 2012

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

scientific article published on February 2013

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