List of works - Min Huang

A new nuclease member of the FAN club

scientific article

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

scientific article published on 7 January 2016

Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90.

scientific article

Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2).

scientific article published on 12 April 2016

Exploiting histone deacetylases for cancer therapy: from hematological malignancies to solid tumors.

scientific article published on 23 November 2016

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

scientific article published on September 2016

Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway

scientific article published on 4 October 2011

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

scientific article

Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents.

scientific article published on 4 January 2012

JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification.

scientific article published on 19 October 2015

Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma

scientific article published on 14 May 2015

Metabolic Regulation of CD8⁺ T Cells: From Mechanism to Therapy

scientific article published in 2022

Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells

scientific article published on 25 January 2017

Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.

scientific article

The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response

scientific article

c-Myc alterations confer therapeutic response and acquired resistance to c-Met inhibitors in MET-addicted cancers.

scientific article published on 19 October 2015

List of works by Min Huang

A new nuclease member of the FAN club

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90.

Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2).

Exploiting histone deacetylases for cancer therapy: from hematological malignancies to solid tumors.

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents.

JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification.

Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma

Metabolic Regulation of CD8⁺ T Cells: From Mechanism to Therapy

Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells

Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.

The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response

c-Myc alterations confer therapeutic response and acquired resistance to c-Met inhibitors in MET-addicted cancers.