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List of works by John-Demian Sauer

A Genetic Screen Reveals that Synthesis of 1,4-Dihydroxy-2-Naphthoate (DHNA), but Not Full-Length Menaquinone, Is Required for Listeria monocytogenes Cytosolic Survival

scientific article published on 21 March 2017

A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA.

scientific article

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

scientific article

An in silico screen and structural analysis identifies bacterial kinase inhibitors which act with β-lactams to inhibit mycobacterial growth

scientific article published on 18 October 2018

Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome.

scientific article

Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection

scientific article published on 28 May 2013

Cyclooxygenase-1 and -2 Play Contrasting Roles in Listeria-Stimulated Immunity

scientific article published on 20 April 2018

Differential requirements for NAIP5 in activation of the NLRC4 inflammasome

scientific article published on 31 January 2011

Distinct inflammatory and wound healing responses to complex caudal fin injuries of larval zebrafish

scientific article published in July 2019

Do Shoot the Messenger: PASTA Kinases as Virulence Determinants and Antibiotic Targets.

scientific article

GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against β-Lactam-Resistant Staphylococcus aureus

scientific article published on 15 August 2018

Human Invariant NKT Cells Induce IL-1β Secretion by Peripheral Blood Monocytes via a P2X7-Independent Pathway

scientific article published on 17 August 2016

Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function

scientific article

Listeria monocytogenes and the Inflammasome: From Cytosolic Bacteriolysis to Tumor Immunotherapy

scientific article published on January 2016

Listeria monocytogenes cytosolic metabolism promotes replication, survival, and evasion of innate immunity

scientific article published on 27 June 2017

Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity ⬇️

scientific article published on July 11, 2011

Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol.

scientific article

Listeria monocytogenes-Induced Cell Death Inhibits the Generation of Cell-Mediated Immunity.

scientific article

Listeria monocytogenes: The Impact of Cell Death on Infection and Immunity

scientific article

Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish

scientific article

Mutation of the Transcriptional Regulator YtoI Rescues Listeria monocytogenes Mutants Deficient in the Essential Shared Metabolite 1,4-Dihydroxy-2-Naphthoate (DHNA)

scientific article published on 17 December 2019

Neutrophil derived LTB4 induces macrophage aggregation in response to encapsulated Streptococcus iniae infection

scientific article published on 28 June 2017

Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for β-Lactam-Daptomycin Synergy

scientific article

Role of respiratory NADH oxidation in the regulation of Staphylococcus aureus virulence

scientific article published on 23 March 2020

Selective pharmacologic inhibition of a PASTA kinase increases Listeria monocytogenes susceptibility to β-lactam antibiotics

scientific article

Specificity of Legionella pneumophila and Coxiella burnetii vacuoles and versatility of Legionella pneumophila revealed by coinfection

scientific article

The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity

scientific article published on 09 July 2019

The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence

scientific article

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

scientific article

The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function

scientific article

The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages

scientific article

The phtC-phtD locus equips Legionella pneumophila for thymidine salvage and replication in macrophages

scientific article published on 02 December 2013

Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

scientific article

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