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List of works by Kartik Chandran

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

scientific article published on 04 September 2020

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

scientific article

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants

scientific article published on 05 October 2021

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

scientific article published on 09 July 2019

A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry

scientific article

A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

scientific article published on 03 July 2020

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

scientific article published on 01 August 2018

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

scientific article published on 30 March 2016

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

scientific article published in 2019

A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry

scientific article published on January 2010

A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner.

scientific article published on 9 January 2013

A naturally occurring antiviral ribonucleotide encoded by the human genome

scientific article published in Nature

A replication-competent vesicular stomatitis virus for studies of SARS-CoV-2 spike-mediated cell entry and its inhibition

scientific article published on 21 May 2020

A shared structural solution for neutralizing ebolaviruses

scientific article

A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition

scientific article published on 01 July 2020

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

scientific article published on 03 February 2020

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

scientific article published on 09 July 2019

Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

scientific article published in 2023

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

scientific article published on May 2017

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

scientific article published on 4 May 2016

Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome

scientific article published on 16 June 2020

Author Correction: The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses

scientific article published on 01 December 2018

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses.

scientific article

Broad neutralization of SARS-related viruses by human monoclonal antibodies

scientific article published on 15 June 2020

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

scientific article published on 16 May 2020

C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking

scientific article published on 02 August 2013

Candidate medical countermeasures targeting Ebola virus cell entry

Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants ⬇️

scientific article published on January 7, 2013

Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1.

scientific article

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis

scientific article published on 17 June 2020

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis

scientific article

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1.

scientific article published on 28 January 2014

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids.

scientific article published on 07 May 2013

Crystal Structure of the Marburg Virus GP2 Core Domain in Its Postfusion Conformation

scientific article

Cysteine Cathepsin Inhibitors as Anti-Ebola Agents

scientific article

Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins.

scientific article published on 2 March 2018

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: stability and pH effects

scientific article

Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection

scientific article published in 2019

Development of an antibody cocktail for treatment of Sudan virus infection

scientific article published on 03 February 2020

Development, clinical translation, and utility of a COVID-19 antibody test with qualitative and quantitative readouts

scientific article published on 11 September 2020

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

scientific article published on 9 February 2016

Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013.

scientific article published on April 2014

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

scientific article

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

scientific article

Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells

scientific article published on 01 July 2018

Endocytic pathways involved in filovirus entry: advances, implications and future directions.

scientific article

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

scientific journal article

Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette-Guérin Vaccination to Improve Antiviral Antibody Responses

scientific article published on 08 June 2020

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

scientific article published on 26 September 2014

Filovirus entry into cells – new insights ⬇️

scientific article published on March 23, 2012

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

scientific article

Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences

scientific article published on 11 January 2012

Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response

scientific article published on 25 November 2021

Generation and characterization of protective antibodies to Marburg virus.

scientific article

HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

scientific article published on 01 August 2020

Hantavirus entry: Perspectives and recent advances

scientific article published on 07 August 2019

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

scientific article published on 30 June 2015

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

scientific article

How to turn competitors into collaborators

scientific article published on January 2017

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.

scientific article published on 7 November 2019

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry

scientific article published on 26 April 2019

ICTV Virus Taxonomy Profile: Filoviridae

scientific article published on 25 April 2019

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

scientific article published on 14 January 2019

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients

scientific article published on 21 September 2020

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.

scientific article published on May 2017

Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles.

scientific article

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

scientific article published on 11 May 2017

Inhibition of Ebola virus entry by a C-peptide targeted to endosomes

scientific article

Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

scientific article published on 09 March 2020

Longitudinally monitored immune biomarkers predict the timing of COVID-19 outcomes

scientific article published on 18 January 2022

MAVERICC: Marker-free Vaccinia Virus Engineering of Recombinants through in vitro CRISPR/Cas9 Cleavage

scientific article published on 24 February 2021

Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle

scientific article published on 12 March 2012

Mechanistic and Fc Requirements for Inhibition of Sudan Virus Entry and In Vivo Protection by a Synthetic Antibody.

scientific article published on 7 September 2017

Niemann-Pick C1 (NPC1)/NPC1-like1 chimeras define sequences critical for NPC1's function as a flovirus entry receptor

scientific article published on 25 October 2012

Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.

scientific article published on 26 May 2015

Novel Small Molecule Entry Inhibitors of Ebola Virus.

scientific article published on 22 July 2015

Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice

scientific article published on 08 July 2020

Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials

scientific article

Protocadherin-1 is essential for cell entry by New World hantaviruses

scientific article published in Nature

Publisher Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome

scientific article published in Nature

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

scientific article

Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species

scientific article

Structural basis for antibody-mediated neutralization of Lassa virus

scientific article

Structural basis for differential neutralization of ebolaviruses

scientific article

Structural basis of broad ebolavirus neutralization by a human survivor antibody

scientific article published on 04 March 2019

Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38

scientific article published on 31 March 2020

Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge

scientific article

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Taxonomy of the order Mononegavirales: second update 2018

scientific article published on 01 April 2019

Taxonomy of the order Mononegavirales: update 2016

scientific article published in August 2016

Taxonomy of the order Mononegavirales: update 2017.

scientific article

Taxonomy of the order Mononegavirales: update 2018.

scientific article published on 11 April 2018

Taxonomy of the order Mononegavirales: update 2019

scientific article published on 01 July 2019

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway

scientific article

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism

scientific article published on 09 September 2020

The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses

scientific article published on 27 August 2018

Tracing Transmission of Sin Nombre Virus and Discovery of Infection in Multiple Rodent Species

scientific article published on 22 September 2021

Treatment of Severe COVID-19 with Convalescent Plasma in the Bronx, NYC

scientific article published on 04 December 2020

Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity

scientific article published on 14 October 2021

Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors

scientific article published on 08 January 2019

Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein

scientific article published on 30 October 2012

VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA

scientific article published on 15 April 2020

Vesicular Stomatitis Virus-Based Vaccines Provide Cross-Protection against Andes and Sin Nombre Viruses

scientific article published on 13 July 2019

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

scientific article published on 5 November 2013

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

scientific article published on 29 January 2013

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

scientific article published on 23 September 2012

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