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List of works by Toby Lawrence

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.

scientific article published on August 2014

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

scientific article published on 31 July 2006

Autophagy in dendritic cells.

scientific article

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

scientific article published on 03 February 2014

CANCER: Sex, Cytokines, and Cancer

scientific article published in Science

Chronic inflammation: a failure of resolution?

scientific article published on April 2007

Cigarette smoke induced airway inflammation is independent of NF-κB signalling

scientific article

Coordinated Regulation of Signaling Pathways during Macrophage Activation

scientific article

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

scientific article

GADD45β loss ablates innate immunosuppression in cancer ⬇️

scientific article published on 26 December 2017

Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

scholarly article

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

scientific article published on 7 April 2015

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

scientific article published on 19 February 2013

IKKalpha in the regulation of inflammation and adaptive immunity.

scientific article published in April 2007

Inflammation and cancer: a double-edged sword.

scientific article published on October 2007

Inflammation and cancer: a failure of resolution?

scientific article published on 28 February 2007

Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung

scientific article published on 01 March 2008

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

scientific article

Investigating macrophage and malignant cell interactions in vitro

scientific article published on 01 January 2009

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

scientific article

Macrophage activation and polarization: nomenclature and experimental guidelines

scientific article (publication date: 17 July 2014)

Macrophages and NF-κB in cancer.

scientific article published on January 2011

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

scientific article published on 28 March 2019

Molecular dissection of plasmacytoid dendritic cell activation during a viral infection

scientific article published on 21 August 2018

Novel biphasic role for lymphocytes revealed during resolving inflammation

scientific article published on 24 January 2008

Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase α.

scientific article

Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice

article

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

scientific article published in November 2017

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

scientific article published on 01 June 2018

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma

scientific article published on 13 January 2017

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression

scientific article published on 02 August 2019

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

scientific article published on 20 September 2017

Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

scientific article published on 21 November 2019

The nuclear factor NF-kappaB pathway in inflammation

scientific article

The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity

scientific article

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis

scientific article published on 30 September 2019

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans

scientific article published on 08 September 2009

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.

scientific article

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

scientific article published on 01 April 2020

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles

scientific article published on 16 October 2017

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