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List of works by Manuel Rosa-Calatrava

A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity

scientific article

A functional sequence-specific interaction between influenza A virus genomic RNA segments

scientific article published on 25 September 2013

A quasi-atomic model of human adenovirus type 5 capsid

scientific article published on 21 April 2005

Accelerated mass production of influenza virus seed stocks in HEK-293 suspension cell cultures by reverse genetics

scientific article

Adenovirus infection targets the cellular protein kinase CK2 and RNA-activated protein kinase (PKR) into viral inclusions of the cell nucleus

scientific article published in March 2002

Adenovirus protein IX sequesters host-cell promyelocytic leukaemia protein and contributes to efficient viral proliferation

scientific article

Advances in influenza virus-like particles bioprocesses

scientific article published on 01 December 2019

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

scientific article published on 15 July 2020

Broad-spectrum antiviral activity of naproxen: from Influenza A to SARS-CoV-2 Coronavirus

scientific article published on 02 May 2020

Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway

scientific article

Characterization and Treatment of SARS-CoV-2 in Nasal and Bronchial Human Airway Epithelia

scientific article published on 01 July 2020

Characterization and treatment of SARS-CoV-2 in nasal and bronchial human airway epithelia

scientific article published on 02 April 2020

Characterization of a key residue for hyperfusogenic phenotype in human parainfluenza virus type 2 (hPIV-2) fusion glycoprotein.

scientific article published on 8 June 2013

Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia

scientific article published on 07 August 2019

Cold oxygen plasma technology efficiency against different airborne respiratory viruses.

scientific article

Critical phases of viral production processes monitored by capacitance

scientific article published on 17 November 2016

Critical role of segment-specific packaging signals in genetic reassortment of influenza A viruses

scientific article published on 16 September 2013

Development and pre-clinical evaluation in the swine model of a mucosal vaccine tablet for human influenza viruses: A proof-of-concept study.

scientific article published on 14 January 2018

Drug Repurposing Approaches for the Treatment of Influenza Viral Infection: Reviving Old Drugs to Fight Against a Long-Lived Enemy

scientific article published on 19 March 2019

Engineering of a parainfluenza virus type 5 fusion protein (PIV-5 F): development of an autonomous and hyperfusogenic protein by a combinational mutagenesis approach.

scientific article published on 19 September 2009

Expression and purification of native and functional influenza A virus matrix 2 proton selective ion channel.

scientific article published on 4 November 2016

Extracellular HSP27 mediates angiogenesis through Toll-like receptor 3.

scientific article published on 26 June 2013

Functional analysis of adenovirus protein IX identifies domains involved in capsid stability, transcriptional activity, and nuclear reorganization

scientific article

Gene expression signature-based screening identifies new broadly effective influenza a antivirals

scientific article

Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza.

scientific article

Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a

scientific article published on 23 January 2013

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

scientific article published on 29 July 2020

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

scientific article published on 09 April 2019

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

scientific article published on 22 July 2020

Immune signatures of protective spleen memory CD8 T cells

scientific article

Impact on antiviral resistance of E119V, I222L and R292K substitutions in influenza A viruses bearing a group 2 neuraminidase (N2, N3, N6, N7 and N9).

scientific article published on 17 July 2016

Importance of viral genomic composition in modulating glycoprotein content on the surface of influenza virus particles.

scientific article published on 5 April 2011

In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses

scientific article published on 08 October 2020

In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?

scientific article published on September 2010

In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2

scientific article published on 14 July 2020

Influenza A replication and host nuclear compartments: many changes and many questions.

scientific article published on 16 October 2008

Influenza A viruses alter the stability and antiviral contribution of host E3-ubiquitin ligase Mdm2 during the time-course of infection

scientific article published on 27 February 2018

Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α.

scientific article

Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner.

scientific article published on 13 August 2013

Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues

scientific article published on 14 May 2020

Influenza viruses and mRNA splicing: doing more with less

scientific article published on 13 May 2014

Influenza viruses production: Evaluation of a novel avian cell line DuckCelt®-T17.

scientific article

Isolation of nucleoli

scientific article

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia

scientific article

Novel antiviral compounds and combination therapy for influenza viruses

scientific article published on 01 December 2019

Novel antiviral compounds and combination therapy for influenza viruses

scientific article published in December 2019

Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection

scientific article published on 18 October 2019

Nucleolar localization of a netrin-1 isoform enhances tumor cell proliferation

scientific article

Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication

scientific article

OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes

article

Parainfluenza virus type 5 (PIV-5) morphology revealed by cryo-electron microscopy

scientific article

Purification of ribosomes from human cell lines.

scientific article published on December 2010

RSV Infection in Human Macrophages Promotes CXCL10/IP-10 Expression during Bacterial Co-Infection

scientific article published on 7 December 2017

Recent developments with live-attenuated recombinant paramyxovirus vaccines

scientific article published on 08 May 2012

Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures

article

Role for proteases and HLA-G in the pathogenicity of influenza A viruses.

scientific article

Role of p53/NF-κB functional balance in respiratory syncytial virus-induced inflammation response

scientific article published on 05 March 2018

SPRi-based hemagglutinin quantitative assay for influenza vaccine production monitoring

scientific article published on 14 February 2019

Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development

scientific article published on 30 October 2019

Ten years of human metapneumovirus research.

scientific article

The C-terminal domains of adenovirus serotype 5 protein IX assemble into an antiparallel structure on the facets of the capsid.

scientific article published on 12 November 2008

The NS1 Protein from Influenza Virus Stimulates Translation Initiation by Enhancing Ribosome Recruitment to mRNAs.

scientific article published on 19 April 2017

The Nonstructural NS1 Protein of Influenza Viruses Modulates TP53 Splicing through Host Factor CPSF4

scientific article published on 21 March 2019

The influenza fingerprints: NS1 and M1 proteins contribute to specific host cell ultrastructure signatures upon infection by different influenza A viruses.

scientific article

The product of the adenovirus intermediate gene IX is a transcriptional activator.

scientific article published in July 1997

Timing of antiviral treatment initiation is critical to reduce SARS-CoV-2 viral load

scientific article published on 18 June 2020

Timing of antiviral treatment initiation is critical to reduce SARS-Cov-2 viral load

scientific article published on 07 April 2020

Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir

scientific article published on 09 May 2019

Toxicity of fiber- and penton base-modified adenovirus type 5 vectors on lung development in newborn rats.

scientific article

Transcriptional profiling of immune and inflammatory responses in the context of SARS-CoV-2 fungal superinfection in a human airway epithelial model

scientific article published on 20 May 2020

Ultrastructural fingerprints of avian influenza A (H7N9) virus in infected human lung cells.

scientific article

Viral and bacterial co-infection in severe pneumonia triggers innate immune responses and specifically enhances IP-10: a translational study

scientific article published on 06 December 2016

[A novel mechanism for virally-induced hijacking of p53 identified in the context of influenza virus infection]

scientific article published on 01 February 2020

p53 protein isoforms: key regulators in the front line of pathogen infections?

scientific article

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