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List of works by Peter N Cockerill

A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated interleukin-3 and granulocyte-macrophage colony-stimulating factor genes.

scientific article

A modular enhancer is differentially regulated by GATA and NFAT elements that direct different tissue-specific patterns of nucleosome positioning and inducible chromatin remodeling.

scientific article published on 5 February 2007

A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia.

scientific article published on 26 February 2014

A simplified method for quantitation of the relative amounts of type I and type III collagen in small tissue samples

scientific article published on 01 May 1981

Biochemical and histological changes in pulmonary fibrosis induced in rabbits with intratracheal bleomycin

scientific article published on 01 December 1981

Chromatin Structure Profiling Identifies Crucial Regulators of Tumor Maintenance

scientific article published on 05 November 2015

Chromatin priming elements establish immunological memory in T cells without activating transcription: T cell memory is maintained by DNA elements which stably prime inducible genes without activating steady state transcription.

scientific article published on 27 December 2016

Chromatin priming of genes in development: Concepts, mechanisms and consequences

scientific article published on 6 February 2017

Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature.

scientific article published on 23 July 2015

Comparisons of the structures of the chromosomal high mobility group proteins HMG1 and HMG2 prepared under conditions of neutral and acidic pH

scientific article published on 01 May 1983

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate

scientific article published on 17 October 2016

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

scientific article published on 7 October 2013

Demonstration of an S1-nuclease sensitive site near the human beta-globin gene, and its protection by HMG 1 and 2

scientific article published on 01 April 1983

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

scientific article

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.

scientific article published on 2 May 2010

Fractionation by high-performance liquid chromatography of the low-molecular-mass high-mobility-group (HMG) chromosomal proteins present in proliferating rat cells and an investigation of the HMG proteins present in virus transformed cells.

scientific article

Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication

scientific article published on 01 September 2000

Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma

scientific article published on 13 December 2018

Granulocyte-macrophage colony-stimulating factor enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganization.

scientific article

Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c

scientific article published on April 1995

IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors

scientific article published on 15 September 2020

Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal

scientific article published on 18 September 2014

Inducible chromatin priming is associated with the establishment of immunological memory in T cells.

scientific article

Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192.

scientific article published on 20 July 2012

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

scientific article published on 13 September 2017

Isolation and characterization of the promoter region of the human intercellular adhesion molecule-1 gene

scientific article published on 01 January 1991

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

scientific article

Mechanisms of transcriptional regulation of the human IL-3/GM-CSF locus by inducible tissue-specific promoters and enhancers.

scientific article

NFAT is well placed to direct both enhancer looping and domain-wide models of enhancer function.

scientific article published in April 2008

Octamer-binding proteins in diverse hemopoietic cells.

scientific article published on March 1990

Partial purification of low molecular weight non-suppressible insulin-like activity from human plasma: demonstration of the presence of multiple forms.

scientific article

Prognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature.

scientific article published on 11 September 2017

Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones

scientific article published on 20 September 2018

Protein:DNA interactions at chromosomal loop attachment sites.

scientific article

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.

scientific article

Reconstitution of T cell-specific transcription directed by composite NFAT/Oct elements

scientific article published on 01 November 2000

Rewiring of the Transcription Factor Network in Acute Myeloid Leukemia

scientific article published on 25 June 2019

Role of a 5'-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene

scientific article published on 20 April 2006

Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer

scientific article

Structure and function of active chromatin and DNase I hypersensitive sites.

scientific article published on 26 May 2011

Subtype-specific regulatory network rewiring in acute myeloid leukemia.

scientific article

T Cell Receptor and Cytokine Signaling Can Function at Different Stages to Establish and Maintain Transcriptional Memory and Enable T Helper Cell Differentiation.

scientific article published on 3 March 2017

The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.

scientific article

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

scientific article published on 01 October 2018

The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis.

scientific article published on 4 September 2007

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

scientific article

The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.

scientific article published on 10 February 2010

The human granulocyte-macrophage colony-stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer.

scientific article published on December 1999

Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1.

scientific article published on May 2010

Transcriptional regulation of human CD5: important role of Ets transcription factors in CD5 expression in T cells.

scientific article published on June 2004

Tumor necrosis factor-  induces adhesion molecule expression through the sphingosine kinase pathway

scientific article (publication date: 24 November 1998)

Two methods that facilitate autoradiography of small 32P-labeled DNA fragments following electrophoresis in agarose gels

scientific article published on 01 February 1988

Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors

scientific article published on 25 November 2015

Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data

scientific article