List of works - Caroline Le Van Kim

A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen

scientific article published on 2 February 2015

A recombinant dromedary antibody fragment (VHH or nanobody) directed against human Duffy antigen receptor for chemokines

scientific article

A structural model of a seven-transmembrane helix receptor: the Duffy antigen/receptor for chemokine (DARC).

scientific article published in August 2005

Abnormal properties of red blood cells suggest a role in the pathophysiology of Gaucher disease

scientific article published on 3 December 2012

Aggregation of mononuclear and red blood cells through an {alpha}4{beta}1-Lu/basal cell adhesion molecule interaction in sickle cell disease

scientific article

Ammonium transport properties of HEK293 cells expressing RhCG mutants: preliminary analysis of structure/function by site-directed mutagenesis

scientific article

Antioxidant and Membrane Binding Properties of Serotonin Protect Lipids from Oxidation

scientific article

Arg89Cys substitution results in very low membrane expression of the Duffy antigen/receptor for chemokines in Fy(x) individuals.

scientific article published in September 1998

Cell-derived microparticles and sickle cell disease chronic vasculopathy in sub-Saharan Africa: A multinational study

scientific article published on 29 November 2020

Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein

scientific article (publication date: August 2002)

Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation

scientific article published on 21 June 2010

Dimerization and phosphorylation of Lutheran/basal cell adhesion molecule are critical for its function in cell migration on laminin

scientific article published on 14 August 2019

Direct interaction between the Lu/B-CAM adhesion glycoproteins and erythroid spectrin

scientific article

Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy–negative individuals ⬇️

scientific article published on June 1, 1995

Effect of velaglucerase alfa enzyme replacement therapy on red blood cell properties in Gaucher disease

scientific article published on 16 June 2017

Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia

scientific article

Endothelial Lu/BCAM glycoproteins are novel ligands for red blood cell alpha4beta1 integrin: role in adhesion of sickle red blood cells to endothelial cells

scientific article

Energetic and molecular water permeation mechanisms of the human red blood cell urea transporter B

scientific article

Enhanced calreticulin expression in red cells of polycythemia vera patients harboring the JAK2V617F mutation.

scientific article published on 6 April 2017

Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution.

scientific article

Erythroid Adhesion Molecules in Sickle Cell Anaemia Infants: Insights Into Early Pathophysiology

scientific article published on 18 December 2014

Evidence of a structural and functional ammonium transporter RhBG·anion exchanger 1·ankyrin-G complex in kidney epithelial cells

scientific article

Fine mapping of the Duffy antigen binding site for the Plasmodium vivax Duffy-binding protein

scientific article published in July 2005

Flow cytometry analyses reveal association between Lu/BCAM adhesion molecule and osteonecrosis in sickle cell disease

scientific article published on 01 January 2014

Flow cytometry: retrospective, fundamentals and recent instrumentation.

scientific article

Functional analysis of human RhCG: comparison with E. coli ammonium transporter reveals similarities in the pore and differences in the vestibule

scientific article published on 24 June 2009

Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse

scientific article

Glycophorin C and related glycoproteins: structure, function, and regulation.

scientific article

Glycophorins C and D are generated by the use of alternative translation initiation sites

scientific article published on 01 September 1996

Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells

scientific article

Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation

scientific article

Immunochemical analysis of the Kx protein from human red cells of different Kell phenotypes using antibodies raised against synthetic peptides

scientific article published on 01 March 1997

Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM.

scientific article

Insights into determinants of spleen injury in sickle cell anemia

scientific article published on 01 August 2019

Insights into the Structure and Function of Membrane Polypeptides Carrying Blood Group Antigens ⬇️

scientific article published on January 1, 1998

Isoforms of the Lutheran/basal cell adhesion molecule glycoprotein are differentially delivered in polarized epithelial cells. Mapping of the basolateral sorting signal to a cytoplasmic di-leucine motif.

scientific article published on November 1999

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

scientific article

Lack of G blood group antigen in DIIIberythrocytes is associated with segmental DNA exchange between RH genes

article

Large-scale pre-diagnosis study of fetal RHD genotyping by PCR on plasma DNA from RhD-negative pregnant women

scientific article published in January 2004

Leu110Pro substitution in the RhD polypeptide is responsible for the DVII category blood group phenotype.

scientific article published in May 1995

Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice

scientific article

Metabolic rejuvenation upgrades circulatory functions of red blood cells stored under blood bank conditions

scientific article published on 31 December 2020

Molecular analysis of blood group Rh transcripts from a rGr variant

article

Molecular basis of the RhCW (Rh8) and RhCX (Rh9) blood group specificities

scientific article published on 01 August 1995

Molecular characterization of the Rh-like locus and gene transcripts from the rhesus monkey (Macaca mulatta).

scientific article published in February 1994

Molecular cloning and protein structure of a human blood group Rh polypeptide

scientific article

Multiple Rh messenger RNA isoforms are produced by alternative splicing ⬇️

scientific article (publication date: 15 August 1992)

New insights into red cell rheology and adhesion in patients with sickle cell anaemia during vaso-occlusive crises

scientific article published on 22 November 2018

Noninvasive fetal RHD genotyping from maternal plasma. Use of a new developed Free DNA Fetal Kit RhD.

scientific article published in December 2007

Novel role for the Lu/BCAM-spectrin interaction in actin cytoskeleton reorganization

scientific article published on June 2011

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region

scientific article

PCR-based determination of Rhc and RhE status of fetuses at risk of Rhc and RhE haemolytic disease

scientific article published on 01 September 1994

Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells

scientific article published in 2022

Phosphorylation and ankyrin-G binding of the C-terminal domain regulate targeting and function of the ammonium transporter RhBG

scientific article

Prenatal Determination of Fetal RhD Type by DNA Amplification

scientific article published on 01 August 1993

Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.

scientific article published on 23 June 2005

Rapid Cl⁻/HCO⁻₃exchange kinetics of AE1 in HEK293 cells and hereditary stomatocytosis red blood cells.

scientific article published on 10 July 2013

Rearrangements of the blood group RhD gene associated with the DVI category phenotype

article

Recent advances in molecular and genetic analysis of Rh blood group structures.

scientific article published on January 1993

Red blood cell, a new player in the pathophysiology of Gaucher disease

scientific article published on 20 December 2013

Red cell adhesion in human diseases

scientific article published on May 2014

Red cell and endothelial Lu/BCAM beyond sickle cell disease.

scientific article

Rh haemolytic disease of the newborn and Rh genotyping by RFLP--and allele-specific--PCR.

scientific article published on January 1995

Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation

scientific article

Role of Lu/BCAM glycoproteins in red cell diseases.

scientific article published on 23 July 2010

Role of the interaction between Lu/BCAM and the spectrin-based membrane skeleton in the increased adhesion of hereditary spherocytosis red cells to laminin

scientific article

Sequence, evolution and ligand binding properties of mammalian Duffy antigen/receptor for chemokines

Serotonin is a key factor for mouse red blood cell survival

scientific article

Single-cell analysis of the RhD blood type for use in preimplantation diagnosis in the prevention of severe hemolytic disease of the newborn

scientific article published on 01 February 1995

Specificity and sensitivity of RHD genotyping methods by PCR-based DNA amplification

scientific article published on 01 August 1997

Spherocytic shift of red blood cells during storage provides a quantitative whole cell-based marker of the storage lesion

scientific article published in February 2017

Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria

scientific article published on 4 May 2015

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

scientific article

Structural analysis of the RH-like blood group gene products in nonhuman primates.

scientific article published in January 1995

Structural characterization of the epitope recognized by the new anti-Fy6 monoclonal antibody NaM 185-2C3.

scientific article published in June 2002

Structure-function analysis of the extracellular domains of the Duffy antigen/receptor for chemokines: characterization of antibody and chemokine binding sites

scientific journal article

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.

scientific article published on 19 September 2016

Tentative model for the mapping of D epitopes on the RhD polypeptide

article

The 1.35-kb and 7.5-kb Duffy mRNA isoforms are differently regulated in various regions of brain, differ by the length of their 5' untranslated sequence, but encode the same polypeptide.

scientific article published in October 1997

The Lutheran Blood Group Glycoproteins, the Erythroid Receptors for Laminin, Are Adhesion Molecules ⬇️

scientific article published on July 3, 1998

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells

scientific article

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease

scientific article published on 6 April 2017

The human Kell blood group binds the erythroid 4.1R protein: new insights into the 4.1R-dependent red cell membrane complex

scientific article

The two-gene model of the RH blood-group locus.

scientific article published on March 1995

Transcript analysis of D category phenotypes predicts hybrid Rh D-CE-D proteins associated with alteration of D epitopes.

scientific article published in May 1995

Ubc9 interacts with Lu/BCAM adhesion glycoproteins and regulates their stability at the membrane of polarized MDCK cells

scientific article published in March 2007

Unexpected macrophage-independent dyserythropoiesis in Gaucher disease

scientific article

List of works by Caroline Le Van Kim

A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen

A recombinant dromedary antibody fragment (VHH or nanobody) directed against human Duffy antigen receptor for chemokines

A structural model of a seven-transmembrane helix receptor: the Duffy antigen/receptor for chemokine (DARC).

Abnormal properties of red blood cells suggest a role in the pathophysiology of Gaucher disease

Aggregation of mononuclear and red blood cells through an {alpha}4{beta}1-Lu/basal cell adhesion molecule interaction in sickle cell disease

Ammonium transport properties of HEK293 cells expressing RhCG mutants: preliminary analysis of structure/function by site-directed mutagenesis

Antioxidant and Membrane Binding Properties of Serotonin Protect Lipids from Oxidation

Arg89Cys substitution results in very low membrane expression of the Duffy antigen/receptor for chemokines in Fy(x) individuals.

Cell-derived microparticles and sickle cell disease chronic vasculopathy in sub-Saharan Africa: A multinational study

Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein

Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation

Dimerization and phosphorylation of Lutheran/basal cell adhesion molecule are critical for its function in cell migration on laminin

Direct interaction between the Lu/B-CAM adhesion glycoproteins and erythroid spectrin

Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy–negative individuals ⬇️

Effect of velaglucerase alfa enzyme replacement therapy on red blood cell properties in Gaucher disease

Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia

Endothelial Lu/BCAM glycoproteins are novel ligands for red blood cell alpha4beta1 integrin: role in adhesion of sickle red blood cells to endothelial cells

Energetic and molecular water permeation mechanisms of the human red blood cell urea transporter B

Enhanced calreticulin expression in red cells of polycythemia vera patients harboring the JAK2V617F mutation.

Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution.

Erythroid Adhesion Molecules in Sickle Cell Anaemia Infants: Insights Into Early Pathophysiology

Evidence of a structural and functional ammonium transporter RhBG·anion exchanger 1·ankyrin-G complex in kidney epithelial cells

Fine mapping of the Duffy antigen binding site for the Plasmodium vivax Duffy-binding protein

Flow cytometry analyses reveal association between Lu/BCAM adhesion molecule and osteonecrosis in sickle cell disease

Flow cytometry: retrospective, fundamentals and recent instrumentation.

Functional analysis of human RhCG: comparison with E. coli ammonium transporter reveals similarities in the pore and differences in the vestibule

Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse

Glycophorin C and related glycoproteins: structure, function, and regulation.

Glycophorins C and D are generated by the use of alternative translation initiation sites

Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells

Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation

Immunochemical analysis of the Kx protein from human red cells of different Kell phenotypes using antibodies raised against synthetic peptides

Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin alpha5 chain and Lu/BCAM.

Insights into determinants of spleen injury in sickle cell anemia

Insights into the Structure and Function of Membrane Polypeptides Carrying Blood Group Antigens ⬇️

Isoforms of the Lutheran/basal cell adhesion molecule glycoprotein are differentially delivered in polarized epithelial cells. Mapping of the basolateral sorting signal to a cytoplasmic di-leucine motif.

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

Lack of G blood group antigen in DIIIberythrocytes is associated with segmental DNA exchange between RH genes

Large-scale pre-diagnosis study of fetal RHD genotyping by PCR on plasma DNA from RhD-negative pregnant women

Leu110Pro substitution in the RhD polypeptide is responsible for the DVII category blood group phenotype.

Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice

Metabolic rejuvenation upgrades circulatory functions of red blood cells stored under blood bank conditions

Molecular analysis of blood group Rh transcripts from a rGr variant

Molecular basis of the RhCW (Rh8) and RhCX (Rh9) blood group specificities

Molecular characterization of the Rh-like locus and gene transcripts from the rhesus monkey (Macaca mulatta).

Molecular cloning and protein structure of a human blood group Rh polypeptide

Multiple Rh messenger RNA isoforms are produced by alternative splicing ⬇️

New insights into red cell rheology and adhesion in patients with sickle cell anaemia during vaso-occlusive crises

Noninvasive fetal RHD genotyping from maternal plasma. Use of a new developed Free DNA Fetal Kit RhD.

Novel role for the Lu/BCAM-spectrin interaction in actin cytoskeleton reorganization

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region

PCR-based determination of Rhc and RhE status of fetuses at risk of Rhc and RhE haemolytic disease

Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells

Phosphorylation and ankyrin-G binding of the C-terminal domain regulate targeting and function of the ammonium transporter RhBG

Prenatal Determination of Fetal RhD Type by DNA Amplification

Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.

Rapid Cl⁻/HCO⁻₃exchange kinetics of AE1 in HEK293 cells and hereditary stomatocytosis red blood cells.

Rearrangements of the blood group RhD gene associated with the DVI category phenotype

Recent advances in molecular and genetic analysis of Rh blood group structures.

Red blood cell, a new player in the pathophysiology of Gaucher disease

Red cell adhesion in human diseases

Red cell and endothelial Lu/BCAM beyond sickle cell disease.

Rh haemolytic disease of the newborn and Rh genotyping by RFLP--and allele-specific--PCR.

Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation

Role of Lu/BCAM glycoproteins in red cell diseases.

Role of the interaction between Lu/BCAM and the spectrin-based membrane skeleton in the increased adhesion of hereditary spherocytosis red cells to laminin

Sequence, evolution and ligand binding properties of mammalian Duffy antigen/receptor for chemokines

Serotonin is a key factor for mouse red blood cell survival

Single-cell analysis of the RhD blood type for use in preimplantation diagnosis in the prevention of severe hemolytic disease of the newborn

Specificity and sensitivity of RHD genotyping methods by PCR-based DNA amplification

Spherocytic shift of red blood cells during storage provides a quantitative whole cell-based marker of the storage lesion

Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

Structural analysis of the RH-like blood group gene products in nonhuman primates.

Structural characterization of the epitope recognized by the new anti-Fy6 monoclonal antibody NaM 185-2C3.

Structure-function analysis of the extracellular domains of the Duffy antigen/receptor for chemokines: characterization of antibody and chemokine binding sites

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.

Tentative model for the mapping of D epitopes on the RhD polypeptide

The 1.35-kb and 7.5-kb Duffy mRNA isoforms are differently regulated in various regions of brain, differ by the length of their 5' untranslated sequence, but encode the same polypeptide.